In vitro oxidative inactivation of human presequence protease (hPreP)

Free Radical Biology and Medicine

Volumn 53, Issue 11, 2012, Pages 2188-2195

  Filipe Teixeira, Pedro ^a   Moreira Pinho, Catarina ^a   Branca, Rui M ^b   Lehtiö, Janne ^b   Levine, Rodney L ^c   Glaser, Elzbieta ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Free radicals; Methionine; Mitochondria; Oxidation; Peptide degradation; Presequence protease

Indexed keywords

AMINO ACID; ANTIOXIDANT; HYDROGEN PEROXIDE; LEUCINE; METHIONINE; METHIONINE 206; METHIONINE DERIVATIVE; METHIONINE SULFOXIDE REDUCTASE A; PRESEQUENCE PROTEASE; PROTEINASE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CARBONYLATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRION; OXIDATION; PRIORITY JOURNAL; PROTEIN STABILITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CONSERVED SEQUENCE; HUMANS; HYDROGEN PEROXIDE; KINETICS; METHIONINE SULFOXIDE REDUCTASES; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXIDANTS; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTEOLYSIS; SERINE ENDOPEPTIDASES;

EID: 84868689435     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.09.039     Document Type: Article

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