메뉴 건너뛰기




Volumn 69, Issue 2, 2013, Pages 68-75

Cocktail blood biomarkers: Prediction of clinical outcomes in patients with acute ischemic stroke

Author keywords

Biomarker; Interleukin 6; microRNA; Prognosis; Stroke

Indexed keywords

BIOLOGICAL MARKER; CD40 LIGAND; D DIMER; FIBRIN DEGRADATION PRODUCT; FIBRINOGEN; FRUCTOSE BISPHOSPHATE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MICRORNA 210; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE PLASMINOGEN ACTIVATOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84868686512     PISSN: 00143022     EISSN: 14219913     Source Type: Journal    
DOI: 10.1159/000342896     Document Type: Article
Times cited : (40)

References (41)
  • 1
    • 65549135642 scopus 로고    scopus 로고
    • Blood markers for the prognosis of ischemic stroke: A systematic review
    • Whiteley W, Chong WL, Sengupta A, Sandercock P: Blood markers for the prognosis of ischemic stroke: A systematic review. Stroke 2009; 40:e380-e389
    • (2009) Stroke , vol.40
    • Whiteley, W.1    Chong, W.L.2    Sengupta, A.3    Sandercock, P.4
  • 2
    • 68249139963 scopus 로고    scopus 로고
    • Invited article: Searching for oracles? Blood biomarkers in acute stroke
    • Foerch C, Montaner J, Furie KL, Ning MM, Lo EH: Invited article: Searching for oracles? Blood biomarkers in acute stroke. Neurology 2009; 73: 393-399
    • (2009) Neurology , vol.73 , pp. 393-399
    • Foerch, C.1    Montaner, J.2    Furie, K.L.3    Ning, M.M.4    Lo, E.H.5
  • 3
    • 73449144135 scopus 로고    scopus 로고
    • Stroke biomarkers: Progress and challenges for diagnosis, prognosis, differentiation, and treatment
    • Saenger AK, Christenson RH: Stroke biomarkers: Progress and challenges for diagnosis, prognosis, differentiation, and treatment. Clin Chem 2010; 56: 21-33
    • (2010) Clin Chem , vol.56 , pp. 21-33
    • Saenger, A.K.1    Christenson, R.H.2
  • 4
    • 77949881391 scopus 로고    scopus 로고
    • Neuroinflammation biomarkers
    • Piskunov A: Neuroinflammation biomarkers. Neurochemical Journal 2010; 4: 55-63
    • (2010) Neurochemical Journal , vol.4 , pp. 55-63
    • Piskunov, A.1
  • 5
    • 79960440116 scopus 로고    scopus 로고
    • Dynamics of inflammatory markers in post-Acute stroke patients undergoing rehabilitation
    • Manolescu BN, Berteanu M, Dumitru L, et al: Dynamics of inflammatory markers in post-Acute stroke patients undergoing rehabilitation. Inflammation 2011; 34: 551-558
    • (2011) Inflammation , vol.34 , pp. 551-558
    • Manolescu, B.N.1    Berteanu, M.2    Dumitru, L.3
  • 6
    • 60549115062 scopus 로고    scopus 로고
    • Clinical usefulness of a biomarker-based diagnostic test for acute stroke: The Biomarker Rapid Assessment in Ischemic Injury (BRAIN) study
    • Laskowitz DT, Kasner SE, Saver J, Remmel KS, Jauch EC: Clinical usefulness of a biomarker-based diagnostic test for acute stroke: The Biomarker Rapid Assessment in Ischemic Injury (BRAIN) study. Stroke 2009; 40: 77-85
    • (2009) Stroke , vol.40 , pp. 77-85
    • Laskowitz, D.T.1    Kasner, S.E.2    Saver, J.3    Remmel, K.S.4    Jauch, E.C.5
  • 7
    • 80051549049 scopus 로고    scopus 로고
    • Usefulness of measurement of fibrinogen, D-dimer, D-dimer/fibrinogen ratio, C reactive protein and erythrocyte sedimentation rate to assess the pathophysiology and mechanism of ischaemic stroke
    • Alvarez-Perez FJ, Castelo-Branco M, Alvarez-Sabin J: Usefulness of measurement of fibrinogen, D-dimer, D-dimer/fibrinogen ratio, C reactive protein and erythrocyte sedimentation rate to assess the pathophysiology and mechanism of ischaemic stroke. J Neurol Neurosurg Psychiatry 2011; 82: 986-992
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , pp. 986-992
    • Alvarez-Perez, F.J.1    Castelo-Branco, M.2    Alvarez-Sabin, J.3
  • 8
    • 70349748283 scopus 로고    scopus 로고
    • Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: Relationship with TOAST subtype, outcome and infarct site
    • Tuttolomondo A, Di Sciacca R, Di Raimondo D, et al: Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: Relationship with TOAST subtype, outcome and infarct site. J Neuroimmunol 2009; 215: 84-89
    • (2009) J Neuroimmunol , vol.215 , pp. 84-89
    • Tuttolomondo, A.1    Di Sciacca, R.2    Di Raimondo, D.3
  • 9
    • 84855360164 scopus 로고    scopus 로고
    • The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke
    • Whiteley W, Wardlaw J, Dennis M, et al: The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke. Stroke 2012; 43: 86-91
    • (2012) Stroke , vol.43 , pp. 86-91
    • Whiteley, W.1    Wardlaw, J.2    Dennis, M.3
  • 10
    • 35648951075 scopus 로고    scopus 로고
    • Applicability of biomarkers in ischemic stroke
    • Castellanos M, Serena J: Applicability of biomarkers in ischemic stroke. Cerebrovasc Dis 2007; 24(SUPPL1):7-15
    • (2007) Cerebrovasc Dis , vol.24 , Issue.SUPPL. 1 , pp. 7-15
    • Castellanos, M.1    Serena, J.2
  • 11
    • 79956192318 scopus 로고    scopus 로고
    • Novel situations of endothelial injury in stroke - mechanisms of stroke and strategy of drug development: Novel mechanism of the expression and amplification of cell surface-Associated fibrinolytic activity demonstrated by real-Time imaging analysis
    • Suzuki Y, Urano T: Novel situations of endothelial injury in stroke - mechanisms of stroke and strategy of drug development: Novel mechanism of the expression and amplification of cell surface-Associated fibrinolytic activity demonstrated by real-Time imaging analysis. J Pharmacol Sci 2011; 116: 19-24
    • (2011) J Pharmacol Sci , vol.116 , pp. 19-24
    • Suzuki, Y.1    Urano, T.2
  • 13
    • 59349110661 scopus 로고    scopus 로고
    • Brain inflammation and adult neurogenesis: The dual role of microglia
    • Ekdahl C, Kokaia Z, Lindvall O: Brain inflammation and adult neurogenesis: The dual role of microglia. Neuroscience 2009; 158: 1021-1029
    • (2009) Neuroscience , vol.158 , pp. 1021-1029
    • Ekdahl, C.1    Kokaia, Z.2    Lindvall, O.3
  • 14
    • 80053590072 scopus 로고    scopus 로고
    • MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia
    • Zeng L, Liu J, Wang Y, et al: MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia. Front Biosci (Elite Ed) 2011; 3: 1265-1272
    • (2011) Front Biosci (Elite Ed , vol.3 , pp. 1265-1272
    • Zeng, L.1    Liu, J.2    Wang, Y.3
  • 15
    • 33744779094 scopus 로고    scopus 로고
    • Inflammatory biomarkers in blood of patients with acute brain ischemia
    • Sotgiu S, Zanda B, Marchetti B, et al: Inflammatory biomarkers in blood of patients with acute brain ischemia. Eur J Neurol 2006; 13: 505-513
    • (2006) Eur J Neurol , vol.13 , pp. 505-513
    • Sotgiu, S.1    Zanda, B.2    Marchetti, B.3
  • 17
    • 55049111080 scopus 로고    scopus 로고
    • Pro-inflammatory and antiinflammatory cytokines in acute ischemic stroke and their relation to early neurological deficit and stroke outcome
    • Basic Kes V, Simundic AM, Nikolac N, Topic E, Demarin V: Pro-inflammatory and antiinflammatory cytokines in acute ischemic stroke and their relation to early neurological deficit and stroke outcome. Clin Biochem 2008; 41: 1330-1334
    • (2008) Clin Biochem , vol.41 , pp. 1330-1334
    • Basic Kes, V.1    Simundic, A.M.2    Nikolac, N.3    Topic, E.4    Demarin, V.5
  • 18
    • 0032042208 scopus 로고    scopus 로고
    • Kinetics of IL-8, MIP-1 alpha, TNF alpha, IL-1 beta, IL-1ra and IL-10 in human whole blood samples triggered by smooth and rough LPS
    • Foca A, Berlinghieri MC, Barreca GS, et al: Kinetics of IL-8, MIP-1 alpha, TNF alpha, IL-1 beta, IL-1ra and IL-10 in human whole blood samples triggered by smooth and rough LPS. New Microbiol 1998; 21: 123-130
    • (1998) New Microbiol , vol.21 , pp. 123-130
    • Foca, A.1    Berlinghieri, M.C.2    Barreca, G.S.3
  • 19
    • 0029970407 scopus 로고    scopus 로고
    • LPS induced release of IL-1 beta, IL-6, IL-8 and TNF-Alpha in EDTA or heparin anticoagulated whole blood from persons with high or low levels of serum HDL
    • Eggesbo JB, Hjermann I, Hostmark AT, Kierulf P: LPS induced release of IL-1 beta, IL-6, IL-8 and TNF-Alpha in EDTA or heparin anticoagulated whole blood from persons with high or low levels of serum HDL. Cytokine 1996; 8: 152-160
    • (1996) Cytokine , vol.8 , pp. 152-160
    • Eggesbo, J.B.1    Hjermann, I.2    Hostmark, A.T.3    Kierulf, P.4
  • 20
    • 77950345712 scopus 로고    scopus 로고
    • CD40 ligand and MCP-1 as predictors of cardiovascular events in diabetic patients with stroke
    • Davi G, Tuttolomondo A, Santilli F, et al: CD40 ligand and MCP-1 as predictors of cardiovascular events in diabetic patients with stroke. J Atheroscler Thromb 2009; 16: 707-713
    • (2009) J Atheroscler Thromb , vol.16 , pp. 707-713
    • Davi, G.1    Tuttolomondo, A.2    Santilli, F.3
  • 21
    • 77952513645 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Role of inflammatory cells
    • Jin R, Yang G, Li G: Inflammatory mechanisms in ischemic stroke: Role of inflammatory cells. J Leukoc Biol 2010; 87: 779-789
    • (2010) J Leukoc Biol , vol.87 , pp. 779-789
    • Jin, R.1    Yang, G.2    Li, G.3
  • 22
    • 68349160698 scopus 로고    scopus 로고
    • Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury
    • Shichita T, Sugiyama Y, Ooboshi H, et al: Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med 2009; 15: 946-950
    • (2009) Nat Med , vol.15 , pp. 946-950
    • Shichita, T.1    Sugiyama, Y.2    Ooboshi, H.3
  • 23
    • 67649848277 scopus 로고    scopus 로고
    • IL-17 potentiates neuronal injury induced by oxygen-glucose deprivation and affects neuronal IL-17 receptor expression
    • Wang DD, Zhao YF, Wang GY, et al: IL-17 potentiates neuronal injury induced by oxygen-glucose deprivation and affects neuronal IL-17 receptor expression. J Neuroimmunol 2009; 212: 17-25
    • (2009) J Neuroimmunol , vol.212 , pp. 17-25
    • Wang, D.D.1    Zhao, Y.F.2    Wang, G.Y.3
  • 24
    • 34948909646 scopus 로고    scopus 로고
    • Human TH17 lymphocytes promote bloodbrain barrier disruption and central nervous system inflammation
    • Kebir H, Kreymborg K, Ifergan I, et al: Human TH17 lymphocytes promote bloodbrain barrier disruption and central nervous system inflammation. Nat Med 2007; 13: 1173-1175
    • (2007) Nat Med , vol.13 , pp. 1173-1175
    • Kebir, H.1    Kreymborg, K.2    Ifergan, I.3
  • 25
    • 77953980528 scopus 로고    scopus 로고
    • IL-6: From its discovery to clinical applications
    • Kishimoto T: IL-6: From its discovery to clinical applications. Int Immunol 2010; 22: 347-352
    • (2010) Int Immunol , vol.22 , pp. 347-352
    • Kishimoto, T.1
  • 26
    • 84555205600 scopus 로고    scopus 로고
    • IL-6/IL-6 receptor system and its role in physiological and pathological conditions
    • Mihara M, Hashizume M, Yoshida H, Suzuki M, Shiina M: IL-6/IL-6 receptor system and its role in physiological and pathological conditions. Clin Sci (Lond) 2012; 122: 143-159
    • (2012) Clin Sci (Lond , vol.122 , pp. 143-159
    • Mihara, M.1    Hashizume, M.2    Yoshida, H.3    Suzuki, M.4    Shiina, M.5
  • 27
    • 18944391802 scopus 로고    scopus 로고
    • IL-6: An early marker for outcome in acute ischemic stroke
    • Waje-Andreassen U, Krakenes J, Ulvestad E, et al: IL-6: An early marker for outcome in acute ischemic stroke. Acta Neurol Scand 2005; 111: 360-365
    • (2005) Acta Neurol Scand , vol.111 , pp. 360-365
    • Waje-Andreassen, U.1    Krakenes, J.2    Ulvestad, E.3
  • 29
    • 0033502965 scopus 로고    scopus 로고
    • Increased cytokine release from peripheral blood cells after acute stroke
    • Ferrarese C, Mascarucci P, Zoia C, et al: Increased cytokine release from peripheral blood cells after acute stroke. J Cereb Blood Flow Metab 1999; 19: 1004-1009
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1004-1009
    • Ferrarese, C.1    Mascarucci, P.2    Zoia, C.3
  • 30
    • 0029132696 scopus 로고
    • Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke
    • Tarkowski E, Rosengren L, Blomstrand C, et al: Early intrathecal production of interleukin-6 predicts the size of brain lesion in stroke. Stroke 1995; 26: 1393-1398
    • (1995) Stroke , vol.26 , pp. 1393-1398
    • Tarkowski, E.1    Rosengren, L.2    Blomstrand, C.3
  • 31
    • 70349748283 scopus 로고    scopus 로고
    • Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: Relationship with TOAST subtype, outcome and infarct site
    • Tuttolomondo A, Di Sciacca R, Di Raimondo D, et al: Plasma levels of inflammatory and thrombotic/fibrinolytic markers in acute ischemic strokes: Relationship with TOAST subtype, outcome and infarct site. J Neuroimmunol 2009; 215: 84-89
    • (2009) J Neuroimmunol , vol.215 , pp. 84-89
    • Tuttolomondo, A.1    Di Sciacca, R.2    Di Raimondo, D.3
  • 32
    • 4744356884 scopus 로고    scopus 로고
    • Fibrinogen concentration and risk of ischemic stroke and acute coronary events in 5113 patients with transient ischemic attack and minor ischemic stroke
    • Rothwell PM, Howard SC, Power DA, et al: Fibrinogen concentration and risk of ischemic stroke and acute coronary events in 5113 patients with transient ischemic attack and minor ischemic stroke. Stroke 2004; 35: 2300-2305
    • (2004) Stroke , vol.35 , pp. 2300-2305
    • Rothwell, P.M.1    Howard, S.C.2    Power, D.A.3
  • 33
    • 33645826228 scopus 로고    scopus 로고
    • D-dimer predicts early clinical progression in ischemic stroke: Confirmation using routine clinical assays
    • Barber M, Langhorne P, Rumley A, Lowe GD, Stott DJ: D-dimer predicts early clinical progression in ischemic stroke: Confirmation using routine clinical assays. Stroke 2006; 37: 1113-1115
    • (2006) Stroke , vol.37 , pp. 1113-1115
    • Barber, M.1    Langhorne, P.2    Rumley, A.3    Lowe, G.D.4    Stott, D.J.5
  • 34
    • 0024844738 scopus 로고
    • Effects of FDP and Danshen on renal cortical Na-K-ATPase activity in rats after treatment with renal ischemia and gentamicin
    • Lu FM, Lin SY: Effects of FDP and Danshen on renal cortical Na-K-ATPase activity in rats after treatment with renal ischemia and gentamicin. Chin Med J (Engl) 1989; 102: 516-523
    • (1989) Chin Med J (Engl , vol.102 , pp. 516-523
    • Lu, F.M.1    Lin, S.Y.2
  • 35
    • 0023696720 scopus 로고
    • [Fructose-1,6-diphosphate (FDP) in transitory myocardial ischemia induced by atrial pacing
    • Malusardi R, Oddone A, Orlandi M, Manzi G: [Fructose-1,6-diphosphate (FDP) in transitory myocardial ischemia induced by atrial pacing]. Minerva Cardioangiol 1988; 36: 439-444
    • (1988) Minerva Cardioangiol , vol.36 , pp. 439-444
    • Malusardi, R.1    Oddone, A.2    Orlandi, M.3    Manzi, G.4
  • 36
    • 4444340655 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 as a predictor of ischemic stroke outcome in the elderly
    • Denti L, Annoni V, Cattadori E, et al: Insulin-like growth factor 1 as a predictor of ischemic stroke outcome in the elderly. Am J Med 2004; 117: 312-317
    • (2004) Am J Med , vol.117 , pp. 312-317
    • Denti, L.1    Annoni, V.2    Cattadori, E.3
  • 37
    • 79957649500 scopus 로고    scopus 로고
    • MicroRNA in ischemic stroke etiology and pathology
    • Rink C, Khanna S: MicroRNA in ischemic stroke etiology and pathology. Physiol Genomics 2011; 43: 521-528
    • (2011) Physiol Genomics , vol.43 , pp. 521-528
    • Rink, C.1    Khanna, S.2
  • 38
    • 73949091031 scopus 로고    scopus 로고
    • Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures
    • Liu DZ, Tian Y, Ander BP, et al: Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures. J Cereb Blood Flow Metab 2010; 30: 92-101
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 92-101
    • Liu, D.Z.1    Tian, Y.2    Ander, B.P.3
  • 39
    • 77953483108 scopus 로고    scopus 로고
    • MicroRNA-210: A unique and pleiotropic hypoxamir
    • Chan SY, Loscalzo J: MicroRNA-210: A unique and pleiotropic hypoxamir. Cell Cycle 2010; 9: 1072-1083
    • (2010) Cell Cycle , vol.9 , pp. 1072-1083
    • Chan, S.Y.1    Loscalzo, J.2
  • 40
    • 77957243894 scopus 로고    scopus 로고
    • MicroRNA-210 as a novel therapy for treatment of ischemic heart disease
    • Hu S, Huang M, Li Z, et al: MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation 2010; 122:S124-S131
    • (2010) Circulation , vol.122
    • Hu, S.1    Huang, M.2    Li, Z.3
  • 41
    • 79960536872 scopus 로고    scopus 로고
    • Blood biomarkers for the diagnosis of acute cerebrovascular diseases: A prospective cohort study
    • Whiteley W, Wardlaw J, Dennis M, et al: Blood biomarkers for the diagnosis of acute cerebrovascular diseases: A prospective cohort study. Cerebrovasc Dis 2011; 32: 141-147
    • (2011) Cerebrovasc Dis , vol.32 , pp. 141-147
    • Whiteley, W.1    Wardlaw, J.2    Dennis, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.