The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke

Stroke

Volumn 43, Issue 1, 2012, Pages 86-91

  Whiteley, William ^a   Wardlaw, Joanna ^a   Dennis, Martin ^a   Lowe, Gordon ^b   Rumley, Ann ^b   Sattar, Naveed ^b   Welsh, Paul ^b   Green, Alison ^a   Andrews, Mary ^a   Sandercock, Peter ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

biomarkers; brain infarction; prognosis

Indexed keywords

ADIPONECTIN; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CREATININE; D DIMER; FIBRINOGEN; GELATINASE B; GLUCOSE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 6; PROTEIN S100B; TAU PROTEIN; TROPONIN T; TUMOR NECROSIS FACTOR ALPHA; VON WILLEBRAND FACTOR;

ACUTE DISEASE; ADULT; ARTICLE; BRAIN DAMAGE; BRAIN ISCHEMIA; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HEART STRESS; HOSPITAL ADMISSION; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OUTCOME ASSESSMENT; PATIENT CODING; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; RANKIN SCALE; THROMBOSIS; TRANSIENT ISCHEMIC ATTACK;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BRAIN ISCHEMIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTERLEUKIN-6; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; STROKE;

EID: 84855360164     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.634089     Document Type: Article

References (16)

1. Counsell C, Dennis M, McDowall M. Predicting functional outcome in acute stroke: comparison of a simple six variable model with other predictive systems and informal clinical prediction. J Neurol Neurosurg Psychiatry. 2004;75:401-405. (Pubitemid 38338769)
2. Whiteley W, Chong WL, Sengupta A, Sandercock P. Blood markers for the prognosis of ischemic stroke: a systematic review. Stroke. 2009;40: e380-e389.
3. Welsh P, Barber M, Langhorne P, Rumley A, Lowe GDO, Stott DJ. Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke. Cerebrovasc Dis. 2009;27:247-253.
4. Pepe MS, Janes H, Longton G, Leisenring W, Newcomb P. Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker. Am J Epidemiol. 2004;159:882-890. (Pubitemid 38657490)
5. Konig IR, Ziegler A, Bluhmki E, Hacke W, Bath PMW, Sacco RL, et al. Predicting long-term outcome after acute ischemic stroke: a simple index works in patients from controlled clinical trials. Stroke. 2008;39: 1821-1826.
6. Pencina MJ, D'Agostino RB, D'Agostino RB, Vasan RS. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med. 2008;27:157-172. (Pubitemid 351193639)
7. Bland JM, Altman DG. Multiple significance tests: the Bonferroni method. BMJ. 1995;310:170.
8. Whiteley W, Jackson C, Lewis S, Lowe G, Rumley A, Sandercock P, et al. Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6. PLoS Med. 2009;6: e1000145.
9. Makikallio AM, Makikallio TH, Korpelainen JT, Vuolteenaho O, Tapanainen JM, Ylitalo K, et al. Natriuretic peptides and mortality after stroke. Stroke. 2005;36:1016-1020. (Pubitemid 40629295)
10. Sharma JC, Ananda K, Ross I, Hill R, Vassallo M. N-terminal probrain natriuretic peptide levels predict short-term poststroke survival. J Stroke Cerebrovasc Dis. 2006;15:6.
11. Yip HK, Sun CK, Chang LT, Chen MC, Liou CW. Time course and prognostic value of plasma levels of N-terminal pro-brain natriuretic peptide in patients after ischemic stroke. Circulation. 2006;70:447-452.
12. Efstathiou SP, Tsioulos DI, Tsiakou AG, Gratsias YE, Pefanis AV, Mountokalakis TD. Plasma adiponectin levels and five-year survival after first-ever ischemic stroke. Stroke. 2005;36:1915-1919. (Pubitemid 41266526)
13. Dennis M, Lewis S, Cranswick G, Forbes J. FOOD: a multicentre randomised trial evaluating feeding policies in patients admitted to hospital with a recent stroke. Health Technol Assess. 2006;10:iii-x, 1.
14. Quinn TJ, Dawson J, Walters MR, Lees KR. Reliability of the modified Rankin Scale. Stroke. 2009;40:3393-3395.
15. Tugwell P, Sackett D. How to read clinical journals: III. To learn the clinical course and prognosis of disease. Can Med Assoc J. 1981;124: 869-872.
16. Harrell FE, Lee KL, Mark DB. Multivariable prognostic models:issues in developing models, evaluating assumptions and adequacy and measuring and reducing errors. Stat Med. 1996;15:361-387. (Pubitemid 26072233)