Preliminary evidence of different selection pressures on cancer cells as compared to normal tissues

Theoretical Biology and Medical Modelling

Volumn 9, Issue 1, 2012, Pages

  Ovens, Katie ^a   Naugler, Christopher ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR PROTEIN;

ARTICLE; BIOLOGICAL MODEL; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETIC SELECTION; GENETICS; HUMAN; METABOLISM; MUTATION; NEOPLASM; PATHOLOGY; PHYSIOLOGY;

CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, BIOLOGICAL; MUTATION; NEOPLASM PROTEINS; NEOPLASMS; SELECTION, GENETIC;

EID: 84868650222     PISSN: None     EISSN: 17424682     Source Type: Journal    
DOI: 10.1186/1742-4682-9-44     Document Type: Article

References (27)

1. The clonal evolution of tumor cell populations. Nowell PC, Science 1976 194 23 28
2. Evolutionary biology of cancer. Crespi B, Summers K, Trend Ecol Evol 2005 20 545 552 (Pubitemid 41323711)
3. Cancer as an evolutionary and ecological process. Merlo LM, Pepper JW, Reid BJ, Maley CC, Nat Rev Cancer 2006 6 924 935 (Pubitemid 44862677)
4. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Shackleton M, Quintana E, Fearon ER, Morrison SJ, Cell 2009 138 822 829
5. Patterns of somatic mutation in human cancer genomes. Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, et al. Nature 2007 446 153 158 (Pubitemid 46398669)
6. Genetic instability and Darwinian selection in tumors. Cahill DP, Kinzler KW, Vogelstein B, Lengauer C, Trends Cell Biol. 1999 9 57 M60
7. Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Tao Y, Ruan J, Yeh SH, Lu X, Wang Y, Zhai W, Cai J, Ling S, Gong Q, Chong Z, Qu Z, Li Q, Liu J, Yang J, Zheng C, Zeng C, Wang HY, Zhang J, Wang SH, Hao L, Dong L, Li W, Sun M, Zou W, Yu C, Li C, Liu G, Jiang L, Xu J, Huang H, et al. Proc Natl Acad Sci. USA 2011 108 12042 12047
8. Drug resistance in cancer: principles of emergence and prevention. Komarova N, Wodarz D, Proc Natl Acad Sci USA 2005 102 9714 9719 (Pubitemid 40981746)
9. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Anderson AR, Weaver AM, Cummings PT, Quaranta V, Cell 2006 127 905 915 (Pubitemid 44792251)
10. Population genetics of cancer cell clones: possible implications of cancer stem cells. Naugler CT, Theor Biol Med Model 2010 7 42
11. The onset and extent of genomic instability in sporadic colorectal tumor progression. Stoler DL, Chen N, Basik M, Kahlenberg MS, Rodriguez-Bigas MA, Petrelli NJ, Anderson GR, Proc Natl Acad Sci USA 1999 96 15121 15126 (Pubitemid 30019775)
12. Cosmic: mining complete cancer genomes in the catalogue of somatic mutations in cancer. Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, Jia M, Shepherd R, Leung K, Menzies A, Teague JW, Campbell PJ, Stratton MR, Futreal PA, Nucleic Acids Res. 2011 39 database issue 945 D950
13. The mutation rate and cancer. Jackson AL, Loeb LA, Genetics 1998 148 1483 1490 (Pubitemid 28180678)
14. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Puente XS, Pinyol M, Quesada V, Conde L, Ordóñez GR, Villamor N, Escaramis G, Jares P, Beà S, González-Díaz M, Bassaganyas L, Baumann T, Juan M, López-Guerra M, Colomer D, Tubío JM, López C, Navarro A, Tornador C, Aymerich M, Rozman M, Hernández JM, Puente DA, Freije JM, Velasco G, Gutiérrez-Fernández A, Costa D, Carrió A, Guijarro S, Enjuanes A, et al. Nature 2011 475 101 105
15. how many mutations in a cancer? Tomlinson I, Sagieni P, Bodmer W, Am J Pathol 2002 160 755 758 (Pubitemid 34224563)
16. Identifying cancer driver genes in tumor genome sequencing studies. Youn A, Simon R, Bioinformatics 2011 27 175 181
17. Signatures of mutation and selection in the cancer genome. Bignell GR, Greenman CD, Davies H, Butler AP, Edkins S, Andrews JM, Buck G, Chen L, Beare D, Latimer C, Widaa S, Hinton J, Fahey C, Fu B, Swamy S, Dalgliesh GL, Teh BT, Deloukas P, Yang F, Campbell PJ, Futreal PA, Stratton MR, Nature 2010 463 893 898
18. Molecular signatures of natural selection. Nielson R, Annu Rev Genet 2005 39 197 218
19. Origins and relatedness of human leukocyte antigen Class I supertypes. Naugler C, Hum Immunol 2010 71 837 842
20. MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods. Tamura K, Peterson D, Peterson N, StGecher, Nei M, KuSmar, Mol Biol Evol 2011 28 2731 2739
21. Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Nei M, Gojobori T, Mol Biol Evol 1986 3 418 426 (Pubitemid 16010523)
22. Likelihood models for detecting positively selected amino acid sites and application to the HIV-1 envelope gene. Nielsen R, Yang Z, Genetics 1998 148 929 936 (Pubitemid 28169008)
23. The population genetics of dN/dS. Kryazhimskiy S, Plotkin JB, PLoS Genetics 2008 4 12 1000304
24. The animal within: carcinogenesis and the clonal evolution of cancer cells are speciation events sensu stricto. Vincent MD, Evolution 2010 64 1173 1183
25. Further studies on the nature and causes of gene mutations. Muller HJ, Proceedings of the sixth international congress of genetics Brooklyn Botanic Gardens, Menagha, Wisconsin, Jones DF, 1932 213 255
26. DNA sequencing of a cytogenetically normal acute myeloid leukemia genome. Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore BH, McGrath S, Hickenbotham M, Cook L, Abbott R, Larson DE, Koboldt DC, Pohl C, Smith S, Hawkins A, Abbott S, Locke D, Hillier LW, Miner T, Fulton L, Magrini V, Wylie T, Glasscock J, Conyers J, Sander N, Shi X, Osborne JR, Minx P, et al. Nature 2008 456 66 72
27. A map of human genome variation from population-scale sequencing. The 1000 genomes project consortium, Nature 2010 457 1061 1073