Human embryonic stem cell (hESC) and human embryo research

Pediatrics

Volumn 130, Issue 5, 2012, Pages 972-977

  Denne, Scott C ^a   Bauer, Andrew J ^a   Cabana, Michael D ^a   Cheng, Tina L ^a   Notterman, Daniel A ^a   Scheindlin, Ben ^a   Bergman, Jeffrey J ^a   Fallat, Mary E ^a   Katz, Aviva L ^a   Mercurio, Mark R ^a   Moon, Margaret R ^a   Okun, Alexander L ^a   Webb, Sally A ^a   Weise, Kathryn L ^a  

^a NONE

Author keywords

Embryo; Ethics; Human embryonic stem cell; Stem cell research

Indexed keywords

ADULT STEM CELL; CELL DESTRUCTION; CELL DIFFERENTIATION; CELL ENGINEERING; CELL ISOLATION; CELL LINEAGE; CELL THERAPY; CHILD DEVELOPMENT; CHILD HEALTH; EMBRYO; EMBRYO RESEARCH; EMBRYONIC STEM CELL; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; HUMAN EMBRYO; MEDICAL ETHICS; PLURIPOTENT STEM CELL; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; REVIEW; STEM CELL RESEARCH; TISSUE REGENERATION; TISSUE REPAIR;

EMBRYO RESEARCH; EMBRYONIC STEM CELLS; HUMANS; STEM CELL RESEARCH;

EID: 84868627512     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2012-2482     Document Type: Review

References (31)

1. Lee IS, Jung K, Kim M, Park KI. Neural stem cells: properties and therapeutic potentials for hypoxic-ischemic brain injury in newborn infants. Pediatr Int. 2010;52(6):855-865
2. Tulpule A, Lensch MW, Miller JD, et al. Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage. Blood. 2010;115(17):3453-3462
3. Catalina P, Bueno C, Montes R, et al. Genetic stability of human embryonic stem cells: a first-step toward the development of potential hESC-based systems for modeling childhood leukemia. Leuk Res. 2009;33(7):980-990
4. Pillekamp F, Khalil M, Emmel M, Brockmeier K, Hescheler J. Stem cells in pediatric heart failure. Minerva Cardioangiol. 2008; 56(3):335 -348
5. Leist M, Bremer S, Brundin P, et al. The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy. ALTEX. 2008;25 (3):163-190
6. Ebert AD, Svendsen CN. Human stem cells and drug screening: opportunities and challenges. Nat Rev Drug Discov. 2010;9(5): 367-372
7. Maury Y, Gauthier M, Peschanski M, Martinat C. Human pluripotent stem cells for disease modelling and drug screening. Bioessays . 2012;34(1):61-71
8. National Institutes of Health. Stem cell information page. Available at: http://stemcells.nih.gov. Accessed January 3, 2012
9. Zhang X, Stojkovic P, Przyborski S, et al. Derivation of human embryonic stem cells from developing and arrested embryos. Stem Cells. 2006;24(12):2669-2676 (Pubitemid 46070118)
10. Klimanskaya I, Chung Y, Becker S, Lu SJ, Lanza R. Human embryonic stem cell lines derived from single blastomeres. Nature. 2006;444(7118):481-485 (Pubitemid 44809064)
11. Watson RA, Yeung TM. What is the potential of oligodendrocyte progenitor cells to successfully treat human spinal cord injury? BMC Neurol. 2011;11:113
12. Hester ME, Murtha MJ, Song S, et al. Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes. Mol Ther. 2011;19(10):1905-1912
13. Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science . 2007; 318(5858):1917-1920
14. Grabel L. Prospects for pluripotent stem cell therapies: into the clinic and back to the bench. J Cell Biochem. 2012;113(2):381-387
15. Aziz-Aloya RB, Levanon D, Karn H, et al. Expression of AML1-d, a short human AML1 isoform, in embryonic stem cells suppresses in vivo tumor growth and differentiation. Cell Death Differ. 1998;5(9):765-773 (Pubitemid 28439117)
16. Szabo E, Rampalli S, Risueño RM, et al. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature. 2010;468(7323):521-526
17. Agarwal S, Loh YH, McLoughlin EM, et al. Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. Nature. 2010;464(7286):292-296
18. Marchetto MC, Carromeu C, Acab A, et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell. 2010;143(4):527-539
19. Tsuji O, Miura K, Fujiyoshi K, Momoshima S, Nakamura M, Okano H. Cell therapy for spinal cord injury by neural stem/ progenitor cells derived from iPS/ES cells. Neurotherapeutics. 2011;8(4):668-676
20. Chaudhury H, Raborn E, Goldie LC, Hirschi KK. Stem cell-derived vascular endothelial cells and their potential application in regenerative medicine. Cells Tissues Organs. 2012;195(1-2):41-47
21. Kim K, Doi A, Wen B, et al. Epigenetic memory in induced pluripotent stem cells. Nature. 2010;467(7313):285-290
22. Stadtfeld M, Apostolou E, Akutsu H, et al. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature. 2010;465(7295): 175-181
23. Urbach A, Bar-Nur O, Daley GQ, Benvenisty N. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell. 2010;6(5):407-411
24. Hyun I, Li W, Ding S. Scientific and ethical reasons why iPS cell research must proceed with human embryonic stem cell research. Stanford J Law Sci Policy. 2010;3: 43-48 Epub November 2010
25. Wang D, Haviland DL, Burns AR, Zsigmond E, Wetsel RA. A pure population of lung alveolar epithelial type II cells derived from human embryonic stem cells. Proc Natl Acad Sci USA. 2007;104(11):4449-4454 (Pubitemid 47186246)
26. D'Amour KA, Bang AG, Eliazer S, et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol. 2006;24(11): 1392-1401 (Pubitemid 44722103)
27. Guenou H, Nissan X, Larcher F, et al. Human embryonic stem-cell derivatives for full reconstruction of the pluristratified epidermis: a preclinical study. Lancet. 2009; 374(9703):1745-1753
28. Woll PS, Grzywacz B, Tian X, et al. Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity. Blood. 2009;113(24):6094-6101
29. American College of Obstetricians and Gynecologists, Committee on Ethics. ACOG Committee Opinion 347: Using Preimplantation Embryos for Research. Washington, DC: American College of Obstetricians and Gynecologists; 2006
30. Hyun I. The bioethics of iPS cell-based drug discovery. Clin Pharmacol Ther. 2011;89(5): 646-647
31. Evans MD, Kelley J. US attitudes toward human embryonic stem cell research. Nat Biotechnol. 2011;29(6):484-488