메뉴 건너뛰기




Volumn 78, Issue 21, 2012, Pages 7557-7563

Deletion of the Aspergillus flavus orthologue of A. Nidulans fluG reduces conidiation and promotes production of sclerotia but does not abolish aflatoxin biosynthesis

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN BIOSYNTHESIS; ASPERGILLUS FLAVUS; ASPERGILLUS NIDULANS; CONIDIATION; DEVELOPMENTAL CHANGES; DIFFUSIBLE SIGNALS; GENE CONTROLLING; POTATO DEXTROSE AGARS; SECONDARY METABOLITES; SIGNALING PATHWAYS;

EID: 84868620925     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.01241-12     Document Type: Article
Times cited : (77)

References (44)
  • 1
    • 0024299512 scopus 로고
    • brlA is necessary and sufficient to direct conidiophore development in Aspergillus nidulans
    • Adams TH, Boylan MT, Timberlake WE. 1988. brlA is necessary and sufficient to direct conidiophore development in Aspergillus nidulans. Cell. 54:353-362.
    • (1988) Cell , vol.54 , pp. 353-362
    • Adams, T.H.1    Boylan, M.T.2    Timberlake, W.E.3
  • 2
    • 0026706867 scopus 로고
    • Isolation of a gene required for programmed initiation of development by Aspergillus nidulans
    • Adams TH, Hide WA, Yager LN, Lee BN. 1992. Isolation of a gene required for programmed initiation of development by Aspergillus nidulans. Mol. Cell. Biol. 12:3827-3833.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3827-3833
    • Adams, T.H.1    Hide, W.A.2    Yager, L.N.3    Lee, B.N.4
  • 3
    • 0027262430 scopus 로고
    • Spatial and temporal controls of the Aspergillus brlA developmental regulatory gene
    • Aguirre J. 1993. Spatial and temporal controls of the Aspergillus brlA developmental regulatory gene. Mol. Microbiol. 8:211-218.
    • (1993) Mol. Microbiol. , vol.8 , pp. 211-218
    • Aguirre, J.1
  • 4
    • 0028278743 scopus 로고
    • The Aspergillus nidulans abaA gene encodes a transcriptional activator that acts as a genetic switch to control development
    • Andrianopoulos A, Timberlake WE. 1994. The Aspergillus nidulans abaA gene encodes a transcriptional activator that acts as a genetic switch to control development. Mol. Cell. Biol. 14:2503-2515.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2503-2515
    • Andrianopoulos, A.1    Timberlake, W.E.2
  • 5
    • 45849147020 scopus 로고    scopus 로고
    • VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism
    • Bayram O, et al. 2008. VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism. Science. 320:1504-1506.
    • (2008) Science , vol.320 , pp. 1504-1506
    • Bayram, O.1
  • 6
    • 4143090400 scopus 로고    scopus 로고
    • LaeA, a regulator of secondary metabolism in Aspergillus spp
    • Bok JW, Keller NP. 2004. LaeA, a regulator of secondary metabolism in Aspergillus spp. Eukaryot. Cell 3:527-535.
    • (2004) Eukaryot.Cell , vol.3 , pp. 527-535
    • Bok, J.W.1    Keller, N.P.2
  • 7
    • 34748920932 scopus 로고    scopus 로고
    • Aspergillus nidulans conidiation genes dewA, fluG, and stuA are differentially regulated in early vegetative growth
    • Breakspear A, Momany M. 2007. Aspergillus nidulans conidiation genes dewA, fluG, and stuA are differentially regulated in early vegetative growth. Eukaryot. Cell. 6:1697-1700.
    • (2007) Eukaryot. Cell , vol.6 , pp. 1697-1700
    • Breakspear, A.1    Momany, M.2
  • 8
    • 67650239848 scopus 로고    scopus 로고
    • Melanin synthesis by Sclerotinia sclerotiorum
    • Butler MJ, Gardiner RB, Day AW. 2009. Melanin synthesis by Sclerotinia sclerotiorum. Mycologia. 101:296-304.
    • (2009) Mycologia , vol.101 , pp. 296-304
    • Butler, M.J.1    Gardiner, R.B.2    Day, A.W.3
  • 9
    • 0036009093 scopus 로고    scopus 로고
    • Association of aflatoxin biosynthesis and sclerotial development in Aspergillus parasiticus
    • Chang P-K, Bennett JW, Cotty PJ. 2002. Association of aflatoxin biosynthesis and sclerotial development in Aspergillus parasiticus. Mycopathologia. 153:41-48.
    • (2002) Mycopathologia , vol.153 , pp. 41-48
    • Chang, P.-K.1    Bennett, J.W.2    Cotty, P.J.3
  • 10
    • 33645873258 scopus 로고    scopus 로고
    • Cladal relatedness among Aspergillus oryzae isolates and Aspergillus flavus S and L morphotype isolates
    • Chang P-K, Ehrlich KC, Hua SS. 2006. Cladal relatedness among Aspergillus oryzae isolates and Aspergillus flavus S and L morphotype isolates. Int. J. Food Microbiol. 108:172-177.
    • (2006) Int. J. Food Microbiol. , vol.108 , pp. 172-177
    • Chang, P.-K.1    Ehrlich, K.C.2    Hua, S.S.3
  • 11
    • 84856360317 scopus 로고    scopus 로고
    • Effects of laeA deletion on Aspergillus flavus conidial development and hydrophobicity may contribute to loss of aflatoxin production
    • Chang P-K, et al. 2012. Effects of laeA deletion on Aspergillus flavus conidial development and hydrophobicity may contribute to loss of aflatoxin production. Fungal Biol. 116:298-307.
    • (2012) Fungal Biol. , vol.116 , pp. 298-307
    • Chang, P.-K.1
  • 12
    • 77952582442 scopus 로고    scopus 로고
    • Development and refinement of a high-efficiency gene-targeting system for Aspergillus flavus
    • Chang P-K, Scharfenstein LL, Wei Q, Bhatnagar D. 2010. Development and refinement of a high-efficiency gene-targeting system for Aspergillus flavus. J. Microbiol. Methods. 81:240-246.
    • (2010) J. Microbiol. Methods. , vol.81 , pp. 240-246
    • Chang, P.-K.1    Scharfenstein, L.L.2    Wei, Q.3    Bhatnagar, D.4
  • 13
    • 0001698624 scopus 로고
    • Virulence and cultural characteristics of two Aspergillus flavus strains pathogenic on cotton
    • Cotty PJ. 1989. Virulence and cultural characteristics of two Aspergillus flavus strains pathogenic on cotton. Phytopathology. 79:808-814.
    • (1989) Phytopathology , vol.79 , pp. 808-814
    • Cotty, P.J.1
  • 14
    • 80052065326 scopus 로고    scopus 로고
    • A nodulin/glutamine synthetase-like fusion protein is implicated in the regulation of root morphogenesis and in signalling triggered by flagellin
    • Doskocilova A, et al. 2011. A nodulin/glutamine synthetase-like fusion protein is implicated in the regulation of root morphogenesis and in signalling triggered by flagellin. Planta. 234:459-476.
    • (2011) Planta , vol.234 , pp. 459-476
    • Doskocilova, A.1
  • 15
    • 0034919715 scopus 로고    scopus 로고
    • Characterization of the role of the FluG protein in asexual development of Aspergillus nidulans
    • D'Souza CA, Lee BN, Adams TH. 2001. Characterization of the role of the FluG protein in asexual development of Aspergillus nidulans. Genetics. 158:1027-1036.
    • (2001) Genetics , vol.158 , pp. 1027-1036
    • D'souza, C.A.1    Lee, B.N.2    Adams, T.H.3
  • 16
    • 33845736981 scopus 로고    scopus 로고
    • Production of cyclopiazonic acid, aflatrem, and aflatoxin by Aspergillus flavus is regulated by veA, a gene necessary for sclerotial formation
    • Duran RM, Cary JW, Calvo AM. 2007. Production of cyclopiazonic acid, aflatrem, and aflatoxin by Aspergillus flavus is regulated by veA, a gene necessary for sclerotial formation. Appl. Microbiol. Biotechnol. 73:1158-1168.
    • (2007) Appl. Microbiol. Biotechnol. , vol.73 , pp. 1158-1168
    • Duran, R.M.1    Cary, J.W.2    Calvo, A.M.3
  • 17
    • 78649335073 scopus 로고    scopus 로고
    • Aspergillus nidulans asexual development: making the most of cellular modules
    • Etxebeste O, Garzia A, Espeso EA, Ugalde U. 2010. Aspergillus nidulans asexual development: making the most of cellular modules. Trends Microbiol.18:569-576.
    • (2010) Trends Microbiol. , vol.18 , pp. 569-576
    • Etxebeste, O.1    Garzia, A.2    Espeso, E.A.3    Ugalde, U.4
  • 18
    • 28844461287 scopus 로고    scopus 로고
    • Sequencing of Aspergillus nidulans and comparative analysis with A
    • Galagan JE, et al. 2005. Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature. 438:1105-1115.
    • (2005) fumigatus and A. oryzae. Nature , vol.438 , pp. 1105-1115
    • Galagan, J.E.1
  • 20
    • 0030839254 scopus 로고    scopus 로고
    • Aspergillus sporulation and mycotoxin production both require inactivation of the FadA Gα protein- dependent signaling pathway
    • Hicks JK, Yu JH, Keller NP, Adams TH. 1997. Aspergillus sporulation and mycotoxin production both require inactivation of the FadA Gα protein- dependent signaling pathway. EMBO J. 16:4916-4923.
    • (1997) EMBO J. , vol.16 , pp. 4916-4923
    • Hicks, J.K.1    Yu, J.H.2    Keller, N.P.3    Adams, T.H.4
  • 21
    • 67650221600 scopus 로고    scopus 로고
    • Sexual reproduction in Aspergillus flavus
    • Horn BW, Moore GG, Carbone I. 2009. Sexual reproduction in Aspergillus flavus. Mycologia. 101:423-429.
    • (2009) Mycologia. , vol.101 , pp. 423-429
    • Horn, B.W.1    Moore, G.G.2    Carbone, I.3
  • 22
    • 72949106699 scopus 로고    scopus 로고
    • Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferaselike domains: synthesis of novel metabolites and peptide modifications of proteins
    • Iyer LM, Abhiman S, Maxwell Burroughs A, Aravind L. 2009. Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferaselike domains: synthesis of novel metabolites and peptide modifications of proteins. Mol. Biosyst. 5:1636-1660.
    • (2009) Mol. Biosyst. , vol.5 , pp. 1636-1660
    • Iyer, L.M.1    Abhiman, S.2    Burroughs, A.M.3    Aravind, L.4
  • 23
    • 79960120484 scopus 로고    scopus 로고
    • SclR, a basic helix-loop-helix transcription factor, regulates hyphal morphology and promotes sclerotial formation in Aspergillus oryzae
    • Jin FJ, et al. 2011. SclR, a basic helix-loop-helix transcription factor, regulates hyphal morphology and promotes sclerotial formation in Aspergillus oryzae. Eukaryot. Cell. 10:945-955.
    • (2011) Eukaryot. Cell , vol.10 , pp. 945-955
    • Jin, F.J.1
  • 24
    • 53049091681 scopus 로고    scopus 로고
    • Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus
    • Kale SP, et al. 2008. Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus. Fungal Genet. Biol. 45:1422-1429.
    • (2008) Fungal Genet. Biol. , vol.45 , pp. 1422-1429
    • Kale, S.P.1
  • 25
    • 0036392324 scopus 로고    scopus 로고
    • The veA gene activates sexual development in Aspergillus nidulans
    • Kim H, et al. 2002. The veA gene activates sexual development in Aspergillus nidulans. Fungal Genet. Biol. 37:72-80.
    • (2002) Fungal Genet. Biol. , vol.37 , pp. 72-80
    • Kim, H.1
  • 26
    • 0001703386 scopus 로고
    • The Aspergillus nidulans fluG gene is required for production of an extracellular developmental signal and is related to prokaryotic glutamine synthetase I
    • Lee BN, Adams TH. 1994. The Aspergillus nidulans fluG gene is required for production of an extracellular developmental signal and is related to prokaryotic glutamine synthetase I. Genes Dev. 8:641-651.
    • (1994) Genes Dev. , vol.8 , pp. 641-651
    • Lee, B.N.1    Adams, T.H.2
  • 27
    • 0029671053 scopus 로고    scopus 로고
    • FluG and FlbA function interdependently to initiate conidiophore development in Aspergillus nidulans through brlA beta activation
    • Lee BN, Adams TH. 1996. FluG and FlbA function interdependently to initiate conidiophore development in Aspergillus nidulans through brlA beta activation. EMBO J. 15:299-309.
    • (1996) EMBO J. , vol.15 , pp. 299-309
    • Lee, B.N.1    Adams, T.H.2
  • 28
    • 33750385580 scopus 로고    scopus 로고
    • Upstream and downstream regulation of asexual development in Aspergillus fumigatus
    • Mah JH, Yu JH. 2006. Upstream and downstream regulation of asexual development in Aspergillus fumigatus. Eukaryot. Cell. 5:1585-1595.
    • (2006) Eukaryot. Cell , vol.5 , pp. 1585-1595
    • Mah, J.H.1    Yu, J.H.2
  • 29
    • 0026077954 scopus 로고
    • Aspergillus nidulans wetA activates spore-specific gene expression
    • Marshall MA, Timberlake WE. 1991. Aspergillus nidulans wetA activates spore-specific gene expression. Mol. Cell. Biol. 11:55-62.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 55-62
    • Marshall, M.A.1    Timberlake, W.E.2
  • 30
    • 0033933445 scopus 로고    scopus 로고
    • The presence of GSI-like genes in higher plants: support for the paralogous evolution of GSI and GSII genes
    • Mathis R, Gamas P, Meyer Y, Cullimore JV. 2000. The presence of GSI-like genes in higher plants: support for the paralogous evolution of GSI and GSII genes. J. Mol. Evol. 50:116-122.
    • (2000) J. Mol. Evol. , vol.50 , pp. 116-122
    • Mathis, R.1    Gamas, P.2    Meyer, Y.3    Cullimore, J.V.4
  • 31
    • 0024411636 scopus 로고
    • Interactions of three sequentially expressed genes control temporal and spatial specificity in Aspergillus development
    • Mirabito PM, Adams TH, Timberlake WE. 1989. Interactions of three sequentially expressed genes control temporal and spatial specificity in Aspergillus development. Cell. 57:859-868.
    • (1989) Cell , vol.57 , pp. 859-868
    • Mirabito, P.M.1    Adams, T.H.2    Timberlake, W.E.3
  • 32
    • 0025602250 scopus 로고
    • Genetic analysis of suppressors of the veA1 mutation in Aspergillus nidulans
    • Mooney JL, Hassett DE, Yager LN. 1990. Genetic analysis of suppressors of the veA1 mutation in Aspergillus nidulans. Genetics. 126:869-874.
    • (1990) Genetics , vol.126 , pp. 869-874
    • Mooney, J.L.1    Hassett, D.E.2    Yager, L.N.3
  • 33
    • 41549112943 scopus 로고    scopus 로고
    • A novel regulator couples sporogenesis and trehalose biogenesis in Aspergillus nidulans
    • doi:10.1371/ journal.pone.0000970
    • Ni M, Yu JH. 2007. A novel regulator couples sporogenesis and trehalose biogenesis in Aspergillus nidulans. PLoS One. 2:e970. doi:10.1371/ journal.pone.0000970.
    • (2007) PLoS One , vol.2
    • Ni, M.1    Yu, J.H.2
  • 35
    • 33751394705 scopus 로고    scopus 로고
    • Investigation of the functional properties and regulation of three glutamine synthetaselike genes in Streptomyces coelicolor A3(2)
    • Rexer HU, Schaberle T, Wohlleben W, Engels A. 2006. Investigation of the functional properties and regulation of three glutamine synthetaselike genes in Streptomyces coelicolor A3(2). Arch. Microbiol. 186:447-458.
    • (2006) Arch. Microbiol. , vol.186 , pp. 447-458
    • Rexer, H.U.1    Schaberle, T.2    Wohlleben, W.3    Engels, A.4
  • 36
    • 84858667719 scopus 로고    scopus 로고
    • Signaling the induction of sporulation involves the interaction of two secondary metabolites in Aspergillus nidulans
    • Rodriguez-Urra AB, et al. 2012. Signaling the induction of sporulation involves the interaction of two secondary metabolites in Aspergillus nidulans. ACS Chem. Biol. 7:599-606.
    • (2012) ACS Chem. Biol. , vol.7 , pp. 599-606
    • Rodriguez-Urra, A.B.1
  • 37
    • 78650697334 scopus 로고    scopus 로고
    • LaeA control of velvet family regulatory proteins for light-dependent development and fungal cell-type specificity
    • doi:10.1371/journal.pgen.1001226
    • Sarikaya Bayram O, et al. 2010. LaeA control of velvet family regulatory proteins for light-dependent development and fungal cell-type specificity. PLoS Genet. 6:e1001226. doi:10.1371/journal.pgen.1001226.
    • (2010) PLoS Genet , vol.6
    • Sarikaya Bayram, O.1
  • 38
    • 33645237487 scopus 로고    scopus 로고
    • FluG-dependent asexual development in Aspergillus nidulans occurs via derepression
    • Seo JA, Guan Y, Yu JH. 2006. FluG-dependent asexual development in Aspergillus nidulans occurs via derepression. Genetics. 172:1535-1544.
    • (2006) Genetics , vol.172 , pp. 1535-1544
    • Seo, J.A.1    Guan, Y.2    Yu, J.H.3
  • 39
    • 0025465598 scopus 로고
    • abaA controls phialide differentiation in Aspergillus nidulans
    • Sewall TC, Mims CW, Timberlake WE. 1990. abaA controls phialide differentiation in Aspergillus nidulans. Plant Cell. 2:731-739.
    • (1990) Plant Cell , vol.2 , pp. 731-739
    • Sewall, T.C.1    Mims, C.W.2    Timberlake, W.E.3
  • 40
    • 79951486634 scopus 로고    scopus 로고
    • AbaA and WetA govern distinct stages of Aspergillus fumigatus development
    • Tao L, Yu JH. 2011. AbaA and WetA govern distinct stages of Aspergillus fumigatus development. Microbiology. 157:313-326.
    • (2011) Microbiology , vol.157 , pp. 313-326
    • Tao, L.1    Yu, J.H.2
  • 41
    • 0032693329 scopus 로고    scopus 로고
    • A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus
    • Tsai HF, Wheeler MH, Chang YC, Kwon-Chung KJ. 1999. A developmentally regulated gene cluster involved in conidial pigment biosynthesis in Aspergillus fumigatus. J. Bacteriol. 181:6469-6477.
    • (1999) J. Bacteriol. , vol.181 , pp. 6469-6477
    • Tsai, H.F.1    Wheeler, M.H.2    Chang, Y.C.3    Kwon-Chung, K.J.4
  • 42
    • 0028152825 scopus 로고
    • Genetic requirements for initiating asexual development in Aspergillus nidulans
    • III
    • Wieser J, Lee BN, Fondon J, III, Adams TH. 1994. Genetic requirements for initiating asexual development in Aspergillus nidulans. Curr. Genet. 27:62-69.
    • (1994) Curr. Genet. , vol.27 , pp. 62-69
    • Wieser, J.1    Lee, B.N.2    Fondon, J.3    Adams, T.H.4
  • 43
    • 0031879478 scopus 로고    scopus 로고
    • Analysis of fluG mutations that affect light-dependent conidiation in Aspergillus nidulans
    • Yager LN, Lee HO, Nagle DL, Zimmerman JE. 1998. Analysis of fluG mutations that affect light-dependent conidiation in Aspergillus nidulans. Genetics. 149:1777-1786.
    • (1998) Genetics , vol.149 , pp. 1777-1786
    • Yager, L.N.1    Lee, H.O.2    Nagle, D.L.3    Zimmerman, J.E.4
  • 44
    • 79956080442 scopus 로고    scopus 로고
    • Regulation of development in Aspergillus nidulans and Aspergillus fumigatus
    • Yu J-H. 2010. Regulation of development in Aspergillus nidulans and Aspergillus fumigatus. Mycobiology. 38:229-237.
    • (2010) Mycobiology , vol.38 , pp. 229-237
    • Yu, J.-H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.