Transforming growth factor-β from the failing heart leads to squamous metaplasia in human airway cells and in the murine lung

Chest

Volumn 142, Issue 5, 2012, Pages 1274-1283

  Tanabe, Tsuyoshi ^a   Kanoh, Soichiro ^a   Moskowitz, William B ^a   Rubin, Bruce K ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT TRANSFORMING GROWTH FACTOR BETA; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; DOXORUBICIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE (NADP); INVOLUCRIN; PRIMER DNA; PROTEIN PRECURSOR;

AIRWAY REMODELING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS MUCOSA; CARDIAC ASTHMA; CELL TRANSFORMATION; COCULTURE; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; HEART FAILURE; HUMAN; HUMAN CELL; MOUSE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SQUAMOUS CELL METAPLASIA; AIRWAY OBSTRUCTION; ANALYSIS OF VARIANCE; ANIMAL; BRONCHUS; C57BL MOUSE; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; LUNG; MALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AIRWAY OBSTRUCTION; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BRONCHI; COCULTURE TECHNIQUES; DNA PRIMERS; DOXORUBICIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (NADP+); HEART FAILURE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN PRECURSORS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

MLCS; MLOWN;

EID: 84868617831     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.11-1710     Document Type: Article

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