The role of WDR5 in silencing human fetal globin gene expression

Haematologica

Volumn 97, Issue 11, 2012, Pages 1632-1640

  Xu, Zhen ^a   He, Yinghong ^a   Ju, Junyi ^a   Rank, Gerhard ^b   Cerruti, Loretta ^b   Ma, Chi ^a   Simpson, Richard J ^c   Moritz, Robert L ^c   Jane, Stephen M ^b,d   Zhao, Quan ^a  

^a NANJING UNIVERSITY   (China)

^b MONASH UNIVERSITY   (Australia)

^c OLIVIA NEWTON JOHN CANCER RESEARCH INSTITUTE   (Australia)

^d ALFRED HOSPITAL   (Australia)

Author keywords

Human globin gene regulation; Silencing; WDR5

Indexed keywords

HEMOGLOBIN GAMMA CHAIN; HISTONE H3; LENTIVIRUS VECTOR; PROTEIN; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ING2; TRANSCRIPTION FACTOR NFE4; UNCLASSIFIED DRUG; WD40 REPEAT PROTEIN 5;

ARTICLE; CONTROLLED STUDY; GEL PERMEATION CHROMATOGRAPHY; GENE EXPRESSION REGULATION; GENE LOCUS; GENE SILENCING; GENETIC TRANSDUCTION; GLOBIN GENE; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ERYTHROID PRECURSOR CELLS; FEMALE; FETAL GLOBULINS; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HISTONE DEACETYLASE 1; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; K562 CELLS; MALE; METHYLATION; MODELS, BIOLOGICAL; PROMOTER REGIONS, GENETIC; PROTEIN-ARGININE N-METHYLTRANSFERASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TUMOR SUPPRESSOR PROTEINS;

EID: 84868580950     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.061937     Document Type: Article

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