Overexpression of HSPA12B protects against cerebral ischemia/reperfusion injury via a PI3K/Akt-dependent mechanism

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1832, Issue 1, 2013, Pages 57-66

  Ma, Yujie ^a   Lu, Chen ^a,b   Li, Chuanfu ^b   Li, Rongrong ^a   Zhang, Yangyang ^a   Ma, He ^a   Zhang, Xiaojin ^a   Ding, Zhengnian ^a   Liu, Li ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b East Tennessee State University   (United States)

Author keywords

Apoptosis; Cerebral ischemia reperfusion; Heat shock protein A12B (HSPA12B); Neuroprotective agent; PI3K Akt signaling

Indexed keywords

HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN A12B; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE OVEREXPRESSION; INTRACELLULAR SIGNALING; MALE; MOUSE; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; REPERFUSION INJURY;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MALE; MICE; MICE, TRANSGENIC; NEURONS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REPERFUSION INJURY;

MUS; MUS MUSCULUS;

EID: 84868579154     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2012.10.003     Document Type: Article

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