Simvastatin increases circulating endothelial progenitor cells and reduces the formation and progression of diabetic retinopathy in rats

Experimental Eye Research

Volumn 105, Issue , 2012, Pages 1-8

  Zhang, Wei ^a   Yan, Hua ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

animal model; diabetic retinopathy; endothelial progenitor cells; simvastatin

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EVANS BLUE; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; PLATELET ENDOTHELIAL CELL ADHESION MOLECULE 1; SIMVASTATIN; STREPTOZOCIN; VASCULOTROPIN; CD31 ANTIGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NOS2 PROTEIN, RAT; NOS3 PROTEIN, RAT; VASCULAR ENDOTHELIAL GROWTH FACTOR A, RAT; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD RETINA BARRIER; BLOOD VESSEL PERMEABILITY; BODY WEIGHT; CELL MOTILITY; CONTROLLED STUDY; DIABETIC RETINOPATHY; DISEASE COURSE; DRUG EFFECT; ENDOTHELIAL PROGENITOR CELL; FLOW CYTOMETRY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; MALE; MRNA EXPRESSION LEVEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA BLOOD VESSEL; RETINA CAPILLARY; RETINA EDEMA; RETINA TISSUE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; BLOOD; CAPILLARY PERMEABILITY; EXPERIMENTAL DIABETES MELLITUS; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; STEM CELL; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANGIOPOIETIN-1; ANGIOPOIETIN-2; ANIMALS; ANTIGENS, CD31; BLOOD GLUCOSE; BLOOD-RETINAL BARRIER; BODY WEIGHT; CAPILLARY PERMEABILITY; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DISEASE PROGRESSION; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL VESSELS; RNA, MESSENGER; SIMVASTATIN; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84868468334     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2012.09.014     Document Type: Article

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