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Volumn 25, Issue 8, 2012, Pages 731-739

S100A4 regulates motility and invasiveness of human esophageal squamous cell carcinoma through modulating the AKT/Slug signal pathway

Author keywords

AKT; Esophageal squamous cell carcinoma; Metastasis; S100A4; Slug

Indexed keywords

CALVASCULIN; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SLUG; UVOMORULIN;

EID: 84868468237     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2012.01323.x     Document Type: Article
Times cited : (25)

References (40)
  • 2
    • 0026604571 scopus 로고
    • Transformation of normal rat kidney cells by v-K-ras enhances expression of transin 2 and an S-100-related calcium-binding protein
    • De Vouge M W, Mukherjee B B. Transformation of normal rat kidney cells by v-K-ras enhances expression of transin 2 and an S-100-related calcium-binding protein. Oncogene 1992; 7: 109-19.
    • (1992) Oncogene , vol.7 , pp. 109-119
    • De Vouge, M.W.1    Mukherjee, B.B.2
  • 3
    • 21244446530 scopus 로고    scopus 로고
    • The metastasis associated protein S100A4: role in tumour progression and metastasis
    • Helfman D M, Kim E J, Lukanidin E, Grigorian M. The metastasis associated protein S100A4: role in tumour progression and metastasis. Br J Cancer 2005; 92: 1955-8.
    • (2005) Br J Cancer , vol.92 , pp. 1955-1958
    • Helfman, D.M.1    Kim, E.J.2    Lukanidin, E.3    Grigorian, M.4
  • 4
    • 0029091682 scopus 로고
    • Identification and characterization of a fibroblast marker: FSP1
    • Strutz F, Okada H, Lo C W etal. Identification and characterization of a fibroblast marker: FSP1. J Cell Biol 1995; 130: 393-405.
    • (1995) J Cell Biol , vol.130 , pp. 393-405
    • Strutz, F.1    Okada, H.2    Lo, C.W.3
  • 5
    • 43049092564 scopus 로고    scopus 로고
    • S100A4: a common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases?
    • Schneider M, Hansen J L, Sheikh S P. S100A4: a common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases? J Mol Med (Berl) 2008; 86: 507-22.
    • (2008) J Mol Med (Berl) , vol.86 , pp. 507-522
    • Schneider, M.1    Hansen, J.L.2    Sheikh, S.P.3
  • 6
    • 0032532370 scopus 로고    scopus 로고
    • E-cadherin and metastasin (mts-1/S100A4) expression levels are inversely regulated in two tumor cell families
    • Keirsebilck A, Bonne S, Bruyneel E etal. E-cadherin and metastasin (mts-1/S100A4) expression levels are inversely regulated in two tumor cell families. Cancer Res 1998; 58: 4587-91.
    • (1998) Cancer Res , vol.58 , pp. 4587-4591
    • Keirsebilck, A.1    Bonne, S.2    Bruyneel, E.3
  • 7
    • 25444495269 scopus 로고    scopus 로고
    • Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression
    • Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression. Nat Rev Cancer 2005; 5: 744-9.
    • (2005) Nat Rev Cancer , vol.5 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 8
    • 33750717864 scopus 로고    scopus 로고
    • The metastasis-associated gene S100A4 is a novel target of β-catenin/T-cell factor signaling in colon cancer
    • Stein U, Arlt F, Walther W etal. The metastasis-associated gene S100A4 is a novel target of β-catenin/T-cell factor signaling in colon cancer. Gastroenterology 2006; 131: 1486-500.
    • (2006) Gastroenterology , vol.131 , pp. 1486-1500
    • Stein, U.1    Arlt, F.2    Walther, W.3
  • 9
    • 24944450362 scopus 로고    scopus 로고
    • The transcriptional repressor Snail promotes mammary tumor recurrence
    • Moody S E, Perez D, Pan T C etal. The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 2005; 8: 197-209.
    • (2005) Cancer Cell , vol.8 , pp. 197-209
    • Moody, S.E.1    Perez, D.2    Pan, T.C.3
  • 10
    • 77952700605 scopus 로고    scopus 로고
    • Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB
    • Grotterød I, Maelandsmo G M, Boye K. Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB. BMC Cancer 2010; 10: 241.
    • (2010) BMC Cancer , vol.10 , pp. 241
    • Grotterød, I.1    Maelandsmo, G.M.2    Boye, K.3
  • 11
    • 33646253672 scopus 로고    scopus 로고
    • Akt signaling and cancer: surviving but not moving on
    • Toker A, Yoeli-Lerner M. Akt signaling and cancer: surviving but not moving on. Cancer Res 2006; 66: 3963-6.
    • (2006) Cancer Res , vol.66 , pp. 3963-3966
    • Toker, A.1    Yoeli-Lerner, M.2
  • 12
    • 0034798707 scopus 로고    scopus 로고
    • Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition
    • Savagner P. Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition. Bioessays 2001; 23: 912-23.
    • (2001) Bioessays , vol.23 , pp. 912-923
    • Savagner, P.1
  • 13
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • Huber M A, Kraut N, Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 2005; 17: 548-58.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 14
    • 40149110961 scopus 로고    scopus 로고
    • Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma
    • Jethwa P, Naqvi M, Hardy R G etal. Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma. World J Gastroenterol 2008; 14: 1044-52.
    • (2008) World J Gastroenterol , vol.14 , pp. 1044-1052
    • Jethwa, P.1    Naqvi, M.2    Hardy, R.G.3
  • 15
    • 79956227342 scopus 로고    scopus 로고
    • Slug down-regulation by RNA interference inhibits invasion growth in human esophageal squamous cell carcinoma
    • Tang P, Yu Z, Zhang K etal. Slug down-regulation by RNA interference inhibits invasion growth in human esophageal squamous cell carcinoma. BMC Gastroenterol 2011; 11: 60.
    • (2011) BMC Gastroenterol , vol.11 , pp. 60
    • Tang, P.1    Yu, Z.2    Zhang, K.3
  • 16
    • 67049164999 scopus 로고    scopus 로고
    • Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug
    • Saegusa M, Hashimura M, Kuwata T, Okayasu I. Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug. Am J Pathol 2009; 174: 2107-15.
    • (2009) Am J Pathol , vol.174 , pp. 2107-2115
    • Saegusa, M.1    Hashimura, M.2    Kuwata, T.3    Okayasu, I.4
  • 17
    • 64549090709 scopus 로고    scopus 로고
    • Autocrine loop for IGF-I receptor signaling in SLUG-mediated epithelial-mesenchymal transition
    • Sivakumar R, Koga H, Selvendiran K, Maeyama M, Ueno T, Sata M. Autocrine loop for IGF-I receptor signaling in SLUG-mediated epithelial-mesenchymal transition. Int J Oncol 2009; 34: 329-38.
    • (2009) Int J Oncol , vol.34 , pp. 329-338
    • Sivakumar, R.1    Koga, H.2    Selvendiran, K.3    Maeyama, M.4    Ueno, T.5    Sata, M.6
  • 18
    • 70350704818 scopus 로고    scopus 로고
    • Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway
    • Li B, Tsao S W, Li Y Y etal. Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. Int J Cancer 2009; 125: 2576-85.
    • (2009) Int J Cancer , vol.125 , pp. 2576-2585
    • Li, B.1    Tsao, S.W.2    Li, Y.Y.3
  • 19
    • 58649121716 scopus 로고    scopus 로고
    • Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma
    • Wang X C, Wu Y P, Ye B etal. Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma. Mol Cancer Res 2009; 7: 12-22.
    • (2009) Mol Cancer Res , vol.7 , pp. 12-22
    • Wang, X.C.1    Wu, Y.P.2    Ye, B.3
  • 20
    • 0018611964 scopus 로고
    • Characteristics of two cell lines (TE-1 and TE-2) derived from human squamous cell carcinoma of the esophagus
    • Nishihira T, Kasai M, Mori S etal. Characteristics of two cell lines (TE-1 and TE-2) derived from human squamous cell carcinoma of the esophagus. Gann 1979; 70: 575-84.
    • (1979) Gann , vol.70 , pp. 575-584
    • Nishihira, T.1    Kasai, M.2    Mori, S.3
  • 21
    • 65849500423 scopus 로고    scopus 로고
    • Isolation and comparative study of clones from human esophageal carcinoma cell line EC9706
    • Han Y L, Feng Y B, Luo M L, Xu X, Cai Y, Wang M R. Isolation and comparative study of clones from human esophageal carcinoma cell line EC9706. Yi Chuan 2007; 29: 1331-5.
    • (2007) Yi Chuan , vol.29 , pp. 1331-1335
    • Han, Y.L.1    Feng, Y.B.2    Luo, M.L.3    Xu, X.4    Cai, Y.5    Wang, M.R.6
  • 22
    • 12244275736 scopus 로고    scopus 로고
    • Establishment and comparative genomic hybridization analysis of human esophageal carcinomas cell line EC9706
    • Han Y, Wei F, Xu X etal. Establishment and comparative genomic hybridization analysis of human esophageal carcinomas cell line EC9706. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2002; 19: 455-7.
    • (2002) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.19 , pp. 455-457
    • Han, Y.1    Wei, F.2    Xu, X.3
  • 23
    • 34548546555 scopus 로고    scopus 로고
    • Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7
    • Boonstra J J, van der Velden A W, Beerens E C etal. Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7. Cancer Res 2007; 67: 7996-8001.
    • (2007) Cancer Res , vol.67 , pp. 7996-8001
    • Boonstra, J.J.1    van der Velden, A.W.2    Beerens, E.C.3
  • 24
    • 76149146685 scopus 로고    scopus 로고
    • S100A4 and metastasis: a small actor playing many roles
    • Boye K, Maelandsmo G M. S100A4 and metastasis: a small actor playing many roles. Am J Pathol 2010; 176: 528-35.
    • (2010) Am J Pathol , vol.176 , pp. 528-535
    • Boye, K.1    Maelandsmo, G.M.2
  • 25
    • 67349171584 scopus 로고    scopus 로고
    • Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy
    • Sherbet G V. Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy. Cancer Lett 2009; 280: 15-30.
    • (2009) Cancer Lett , vol.280 , pp. 15-30
    • Sherbet, G.V.1
  • 27
    • 78049339481 scopus 로고    scopus 로고
    • Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells
    • Ma X, Yang Y, Wang Y, An G, Lv G. Small interfering RNA-directed knockdown of S100A4 decreases proliferation and invasiveness of osteosarcoma cells. Cancer Lett 2010; 299: 171-81.
    • (2010) Cancer Lett , vol.299 , pp. 171-181
    • Ma, X.1    Yang, Y.2    Wang, Y.3    An, G.4    Lv, G.5
  • 28
    • 77951246515 scopus 로고    scopus 로고
    • Short hairpin RNA-mediated inhibition of S100A4 promotes apoptosis and suppresses proliferation of BGC823 gastric cancer cells in vitro and in vivo
    • Hua J, Chen D, Fu H etal. Short hairpin RNA-mediated inhibition of S100A4 promotes apoptosis and suppresses proliferation of BGC823 gastric cancer cells in vitro and in vivo. Cancer Lett 2010; 292: 41-7.
    • (2010) Cancer Lett , vol.292 , pp. 41-47
    • Hua, J.1    Chen, D.2    Fu, H.3
  • 29
    • 33847223125 scopus 로고    scopus 로고
    • Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo
    • Takenaga K, Nygren J, Zelenina M etal. Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo. Neurobiol Dis 2007; 25: 455-63.
    • (2007) Neurobiol Dis , vol.25 , pp. 455-463
    • Takenaga, K.1    Nygren, J.2    Zelenina, M.3
  • 30
    • 33749516823 scopus 로고    scopus 로고
    • S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9
    • Saleem M, Kweon M H, Johnson J J etal. S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9. Proc Natl Acad Sci U S A 2006; 103: 14825-30.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14825-14830
    • Saleem, M.1    Kweon, M.H.2    Johnson, J.J.3
  • 31
    • 0029912643 scopus 로고    scopus 로고
    • Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene
    • Ambartsumian N S, Grigorian M S, Larsen I F etal. Metastasis of mammary carcinomas in GRS/A hybrid mice transgenic for the mts1 gene. Oncogene 1996; 13: 1621-30.
    • (1996) Oncogene , vol.13 , pp. 1621-1630
    • Ambartsumian, N.S.1    Grigorian, M.S.2    Larsen, I.F.3
  • 32
    • 18144412747 scopus 로고    scopus 로고
    • Suppression of tumor development and metastasis formation in mice lacking the S100A4 (mts1) gene
    • Grum-Schwensen B, Klingelhofer J, Berg C H etal. Suppression of tumor development and metastasis formation in mice lacking the S100A4 (mts1) gene. Cancer Res 2005; 65: 3772-80.
    • (2005) Cancer Res , vol.65 , pp. 3772-3780
    • Grum-Schwensen, B.1    Klingelhofer, J.2    Berg, C.H.3
  • 33
    • 53649103519 scopus 로고    scopus 로고
    • Metastasis and AKT activation
    • Qiao M, Sheng S, Pardee A B. Metastasis and AKT activation. Cell Cycle 2008; 7: 2991-6.
    • (2008) Cell Cycle , vol.7 , pp. 2991-2996
    • Qiao, M.1    Sheng, S.2    Pardee, A.B.3
  • 34
    • 34250744600 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions
    • Doble B W, Woodgett J R. Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions. Cells Tissues Organs 2007; 185: 73-84.
    • (2007) Cells Tissues Organs , vol.185 , pp. 73-84
    • Doble, B.W.1    Woodgett, J.R.2
  • 35
    • 0028318730 scopus 로고
    • Control of cell behavior during vertebrate development by Slug, a zinc finger gene
    • Nieto M A, Sargent M G, Wilkinson D G, Cooke J. Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 1994; 264: 835-9.
    • (1994) Science , vol.264 , pp. 835-839
    • Nieto, M.A.1    Sargent, M.G.2    Wilkinson, D.G.3    Cooke, J.4
  • 36
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra K M, Chen D Y, Fearon E R. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 2002; 62: 1613-18.
    • (2002) Cancer Res , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 37
    • 77949423072 scopus 로고    scopus 로고
    • ERalpha signaling through slug regulates E-cadherin and EMT
    • Ye Y, Xiao Y, Wang W etal. ERalpha signaling through slug regulates E-cadherin and EMT. Oncogene 2010; 29: 1451-62.
    • (2010) Oncogene , vol.29 , pp. 1451-1462
    • Ye, Y.1    Xiao, Y.2    Wang, W.3
  • 38
    • 84655165026 scopus 로고    scopus 로고
    • Slug regulates proliferation and invasiveness of esophageal adenocarcinoma cells in vitro and in vivo
    • Zhang K, Zhang S, Jiao X etal. Slug regulates proliferation and invasiveness of esophageal adenocarcinoma cells in vitro and in vivo. Med Oncol 2010; 28: 1089-100.
    • (2010) Med Oncol , vol.28 , pp. 1089-1100
    • Zhang, K.1    Zhang, S.2    Jiao, X.3
  • 39
    • 28144456743 scopus 로고    scopus 로고
    • Transcription repressor slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma
    • Shih J Y, Tsai M F, Chang T H etal. Transcription repressor slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma. Clin Cancer Res 2005; 11: 8070-8.
    • (2005) Clin Cancer Res , vol.11 , pp. 8070-8078
    • Shih, J.Y.1    Tsai, M.F.2    Chang, T.H.3
  • 40
    • 77949503814 scopus 로고    scopus 로고
    • SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts
    • Lambertini E, Franceschetti T, Torreggiani E etal. SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts. BMC Mol Biol 2010; 11: 13.
    • (2010) BMC Mol Biol , vol.11 , pp. 13
    • Lambertini, E.1    Franceschetti, T.2    Torreggiani, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.