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Volumn 7, Issue 11, 2012, Pages

Dynamic Mechanisms of Cell Rigidity Sensing: Insights from a Computational Model of Actomyosin Networks

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN CROSS LINKING PROTEIN; MOLECULAR MOTOR; MYOSIN ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

EID: 84868372238     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049174     Document Type: Article
Times cited : (62)

References (43)
  • 1
    • 33746593689 scopus 로고    scopus 로고
    • Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis
    • Zaman MH, Trapani LM, Siemeski A, MacKellar D, Gong H, et al. (2006) Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. Proc Natl Acad Sci U S A 103: 13897-13897.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 13897
    • Zaman, M.H.1    Trapani, L.M.2    Siemeski, A.3    MacKellar, D.4    Gong, H.5
  • 2
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • Discher DE, Janmey P, Wang YL, (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310: 1139-1143.
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.L.3
  • 3
    • 0033917881 scopus 로고    scopus 로고
    • Cell movement is guided by the rigidity of the substrate
    • Lo CM, Wang HB, Dembo M, Wang YL, (2000) Cell movement is guided by the rigidity of the substrate. Biophys J 79: 144-152.
    • (2000) Biophys J , vol.79 , pp. 144-152
    • Lo, C.M.1    Wang, H.B.2    Dembo, M.3    Wang, Y.L.4
  • 4
    • 0036794780 scopus 로고    scopus 로고
    • Molecular motors: Force and movement generated by single myosin II molecules
    • Ruegg C, Veigel C, Molloy JE, Schmitz S, Sparrow JC, et al. (2002) Molecular motors: Force and movement generated by single myosin II molecules. News Physiol Sci 17: 213-218.
    • (2002) News Physiol Sci , vol.17 , pp. 213-218
    • Ruegg, C.1    Veigel, C.2    Molloy, J.E.3    Schmitz, S.4    Sparrow, J.C.5
  • 5
    • 4544264684 scopus 로고    scopus 로고
    • Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments
    • Engler AJ, Griffin MA, Sen S, Bonnetnann CG, Sweeney HL, et al. (2004) Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J Cell Biol 166: 877-887.
    • (2004) J Cell Biol , vol.166 , pp. 877-887
    • Engler, A.J.1    Griffin, M.A.2    Sen, S.3    Bonnetnann, C.G.4    Sweeney, H.L.5
  • 6
    • 0346656873 scopus 로고    scopus 로고
    • Regulation of mechanical interactions between fibroblasts and the substratum by stretch-activated Ca2+ entry
    • Munevar S, Wang YL, Dembo M, (2004) Regulation of mechanical interactions between fibroblasts and the substratum by stretch-activated Ca2+ entry. J Cell Sci 117: 85-92.
    • (2004) J Cell Sci , vol.117 , pp. 85-92
    • Munevar, S.1    Wang, Y.L.2    Dembo, M.3
  • 7
    • 0347319161 scopus 로고    scopus 로고
    • Substrate compliance versus ligand density in cell on gel responses
    • Engler A, Bacakova L, Newman C, Hategan A, Griffin M, et al. (2004) Substrate compliance versus ligand density in cell on gel responses. Biophys J 86: 617-628.
    • (2004) Biophys J , vol.86 , pp. 617-628
    • Engler, A.1    Bacakova, L.2    Newman, C.3    Hategan, A.4    Griffin, M.5
  • 8
    • 5044227660 scopus 로고    scopus 로고
    • Elasticity of native and cross-linked polyelectrolyte multilayer films
    • Richert L, Engler AJ, Discher DE, Picart C, (2004) Elasticity of native and cross-linked polyelectrolyte multilayer films. Biomacromolecules 5: 1908-1916.
    • (2004) Biomacromolecules , vol.5 , pp. 1908-1916
    • Richert, L.1    Engler, A.J.2    Discher, D.E.3    Picart, C.4
  • 9
    • 1842502616 scopus 로고    scopus 로고
    • Mechanosensing and mechanochemical transduction: how is mechanical energy sensed and converted into chemical energy in an extracellular matrix?
    • Silver FH, Siperko LM, (2003) Mechanosensing and mechanochemical transduction: how is mechanical energy sensed and converted into chemical energy in an extracellular matrix? Crit Rev Biomed Eng 31: 255-331.
    • (2003) Crit Rev Biomed Eng , vol.31 , pp. 255-331
    • Silver, F.H.1    Siperko, L.M.2
  • 10
    • 3042853029 scopus 로고    scopus 로고
    • Mechanosensitive ion channels: molecules of mechanotransduction
    • Martinac B, (2004) Mechanosensitive ion channels: molecules of mechanotransduction. J Cell Sci 117: 2449-2460.
    • (2004) J Cell Sci , vol.117 , pp. 2449-2460
    • Martinac, B.1
  • 11
    • 23644451510 scopus 로고    scopus 로고
    • A possible unifying principle for mechanosensation
    • Kung C, (2005) A possible unifying principle for mechanosensation. Nature 436: 647-654.
    • (2005) Nature , vol.436 , pp. 647-654
    • Kung, C.1
  • 13
    • 69949183991 scopus 로고    scopus 로고
    • Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I
    • Ren Y, Effler JC, Norstrom M, Luo T, Firtel RA, et al. (2009) Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I. Curr Biol 19: 1421-1428.
    • (2009) Curr Biol , vol.19 , pp. 1421-1428
    • Ren, Y.1    Effler, J.C.2    Norstrom, M.3    Luo, T.4    Firtel, R.A.5
  • 14
    • 84860807182 scopus 로고    scopus 로고
    • Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness
    • Trichet L, Le Digabel J, Hawkins RJ, Vedula SR, Gupta M, et al. (2012) Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness. Proc Natl Acad Sci U S A 109: 6933-6938.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 6933-6938
    • Trichet, L.1    Le Digabel, J.2    Hawkins, R.J.3    Vedula, S.R.4    Gupta, M.5
  • 15
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • Engler AJ, Sen S, Sweeney HL, Discher DE, (2006) Matrix elasticity directs stem cell lineage specification. Cell 126: 677-689.
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 16
    • 28444491145 scopus 로고    scopus 로고
    • Is the mechanical activity of epithelial cells controlled by deformations or forces?
    • Saez A, Buguin A, Silberzan P, Ladoux B, (2005) Is the mechanical activity of epithelial cells controlled by deformations or forces? Biophys J 89: L52-L54.
    • (2005) Biophys J , vol.89
    • Saez, A.1    Buguin, A.2    Silberzan, P.3    Ladoux, B.4
  • 18
    • 33845457715 scopus 로고    scopus 로고
    • Traction forces exerted through N-cadherin contacts
    • Ganz A, Lambert M, Saez A, Silberzan P, Buguin A, et al. (2006) Traction forces exerted through N-cadherin contacts. Biol Cell 98: 721-730.
    • (2006) Biol Cell , vol.98 , pp. 721-730
    • Ganz, A.1    Lambert, M.2    Saez, A.3    Silberzan, P.4    Buguin, A.5
  • 20
    • 32044449220 scopus 로고    scopus 로고
    • Focal adhesions as mechanosensors: The two-spring model
    • Schwarz US, Erdmann T, Bischofs IB, (2006) Focal adhesions as mechanosensors: The two-spring model. Biosystems 83: 225-232.
    • (2006) Biosystems , vol.83 , pp. 225-232
    • Schwarz, U.S.1    Erdmann, T.2    Bischofs, I.B.3
  • 22
    • 80053103556 scopus 로고    scopus 로고
    • Rigidity sensing explained by active matter theory
    • Marcq P, Yoshinaga N, Prost J, (2011) Rigidity sensing explained by active matter theory. Biophys J 101: L33-35.
    • (2011) Biophys J , vol.101
    • Marcq, P.1    Yoshinaga, N.2    Prost, J.3
  • 23
    • 43949122560 scopus 로고    scopus 로고
    • Strain hardening, avalanches, and strain softening in dense cross-linked actin networks
    • Astrom JA, Kumar PBS, Vattulainen I, Karttunen M, (2008) Strain hardening, avalanches, and strain softening in dense cross-linked actin networks. Phys Rev 77: 051913.
    • (2008) Phys Rev , vol.77 , pp. 051913
    • Astrom, J.A.1    Kumar, P.B.S.2    Vattulainen, I.3    Karttunen, M.4
  • 24
    • 77952355776 scopus 로고    scopus 로고
    • A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells
    • Walcott S, Sun SX, (2010) A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells. Proc Natl Acad Sci U S A 107: 7757-7762.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7757-7762
    • Walcott, S.1    Sun, S.X.2
  • 25
    • 58949096791 scopus 로고    scopus 로고
    • Computational Analysis of a Cross-linked Actin-like Network
    • Kim T, Hwang W, Kamm RD, (2009) Computational Analysis of a Cross-linked Actin-like Network. Exp Mech 49: 91-104.
    • (2009) Exp Mech , vol.49 , pp. 91-104
    • Kim, T.1    Hwang, W.2    Kamm, R.D.3
  • 26
    • 68249083215 scopus 로고    scopus 로고
    • Computational Analysis of Viscoelastic Properties of Crosslinked Actin Networks
    • Kim T, Hwang W, Lee H, Kamm RD, (2009) Computational Analysis of Viscoelastic Properties of Crosslinked Actin Networks. PLoS Comput Biol 5: e1000439.
    • (2009) PLoS Comput Biol , vol.5
    • Kim, T.1    Hwang, W.2    Lee, H.3    Kamm, R.D.4
  • 28
    • 79952391679 scopus 로고    scopus 로고
    • An AFM-Based Stiffness Clamp for Dynamic Control of Rigidity
    • Webster KD, Crow A, Fletcher DA, (2011) An AFM-Based Stiffness Clamp for Dynamic Control of Rigidity. PLoS One 6: e17807.
    • (2011) PLoS One , vol.6
    • Webster, K.D.1    Crow, A.2    Fletcher, D.A.3
  • 30
    • 80053373334 scopus 로고    scopus 로고
    • Dynamic Role of Cross-Linking Proteins in Actin Rheology
    • Kim T, Hwang W, Kamm Roger D, (2011) Dynamic Role of Cross-Linking Proteins in Actin Rheology. Biophys J 101: 1597-1603.
    • (2011) Biophys J , vol.101 , pp. 1597-1603
    • Kim, T.1    Hwang, W.2    Kamm Roger, D.3
  • 31
    • 84862023935 scopus 로고    scopus 로고
    • Keratin 8/18 regulation of cell stiffness-extracellular matrix interplay through modulation of Rho-mediated actin cytoskeleton dynamics
    • Bordeleau F, Myrand Lapierre ME, Sheng Y, Marceau N, (2012) Keratin 8/18 regulation of cell stiffness-extracellular matrix interplay through modulation of Rho-mediated actin cytoskeleton dynamics. Plos One 7: e38780.
    • (2012) Plos One , vol.7
    • Bordeleau, F.1    Myrand Lapierre, M.E.2    Sheng, Y.3    Marceau, N.4
  • 32
    • 84859726122 scopus 로고    scopus 로고
    • The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly(ethylene glycol)-based hydrogels
    • Blakney AK, Swartzlander MD, Bryant SJ, (2012) The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly(ethylene glycol)-based hydrogels. J Biomed Mater Res A 100: 1375-1386.
    • (2012) J Biomed Mater Res A , vol.100 , pp. 1375-1386
    • Blakney, A.K.1    Swartzlander, M.D.2    Bryant, S.J.3
  • 33
    • 0032953882 scopus 로고    scopus 로고
    • Length dependence of active force production in skeletal muscle
    • Rassier DE, MacIntosh BR, Herzog W, (1999) Length dependence of active force production in skeletal muscle. J Appl Physiol 86: 1445-1457.
    • (1999) J Appl Physiol , vol.86 , pp. 1445-1457
    • Rassier, D.E.1    MacIntosh, B.R.2    Herzog, W.3
  • 34
    • 79953861194 scopus 로고    scopus 로고
    • Cell shape and substrate rigidity both regulate cell stiffness
    • Tee SY, Fu J, Chen CS, Janmey PA, (2011) Cell shape and substrate rigidity both regulate cell stiffness. Biophys J 100: L25-27.
    • (2011) Biophys J , vol.100
    • Tee, S.Y.1    Fu, J.2    Chen, C.S.3    Janmey, P.A.4
  • 35
    • 32344453990 scopus 로고    scopus 로고
    • Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells
    • Gardel ML, Nakamura F, Hartwig JH, Crocker JC, Stossel TP, et al. (2006) Prestressed F-actin networks cross-linked by hinged filamins replicate mechanical properties of cells. Proc Natl Acad Sci U S A 103: 1762-1767.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 1762-1767
    • Gardel, M.L.1    Nakamura, F.2    Hartwig, J.H.3    Crocker, J.C.4    Stossel, T.P.5
  • 36
    • 34548727516 scopus 로고    scopus 로고
    • Blebbistatin specifically inhibits actin-myosin interaction in mouse cardiac muscle
    • Dou Y, Arlock P, Arner A, (2007) Blebbistatin specifically inhibits actin-myosin interaction in mouse cardiac muscle. AM J Physiol-Cell Ph 293: C1148-C1153.
    • (2007) AM J Physiol-Cell Ph , vol.293
    • Dou, Y.1    Arlock, P.2    Arner, A.3
  • 38
    • 0042925433 scopus 로고    scopus 로고
    • Cell organization in soft media due to active mechanosensing
    • Bischofs IB, Schwarz US, (2003) Cell organization in soft media due to active mechanosensing. Proc Natl Acad Sci U S A 100: 9274-9279.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9274-9279
    • Bischofs, I.B.1    Schwarz, U.S.2
  • 39
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • Pelham RJ, Wang YL, (1997) Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A 94: 13661-13665.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13661-13665
    • Pelham, R.J.1    Wang, Y.L.2
  • 40
    • 24944546618 scopus 로고    scopus 로고
    • Physical determinants of cell organization in soft media
    • Schwarz US, Bischofs IB, (2005) Physical determinants of cell organization in soft media. Med Eng Phys 27: 763-772.
    • (2005) Med Eng Phys , vol.27 , pp. 763-772
    • Schwarz, U.S.1    Bischofs, I.B.2
  • 42
    • 0000682154 scopus 로고
    • The heat of shortening and the dynamic constants of muscle
    • Hill AV, (1938) The heat of shortening and the dynamic constants of muscle. P Roy Soc Lond B Bio 126: 136-195.
    • (1938) P Roy Soc Lond B Bio , vol.126 , pp. 136-195
    • Hill, A.V.1
  • 43
    • 84868362917 scopus 로고
    • Muscles, Reflexes, and Locomotion
    • McMahon T, (1985) Muscles, Reflexes, and Locomotion. Percept Motor Skill 60: 679-679.
    • (1985) Percept Motor Skill , vol.60 , pp. 679
    • McMahon, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.