메뉴 건너뛰기




Volumn 26, Issue 11, 2012, Pages 4390-4399

Developing T-cell migration: Role of semaphorins and ephrins

Author keywords

Ephs; Neuropilins; Thymic epithelial cells; Thymocyte migration; Thymus

Indexed keywords

CHEMOKINE; EPHRIN; EPHRIN A1; EPHRIN A2; EPHRIN A3; EPHRIN A4; EPHRIN A5; EPHRIN B1; EPHRIN B2; EPHRIN B3; NEUROPILIN; PLEXIN; PLEXIN A1; PLEXIN A2; PLEXIN D1; SCLEROPROTEIN; SEMAPHORIN; SEMAPHORIN 3A; SEMAPHORIN 3E; SEMAPHORIN 3F; SEMAPHORIN 4D; SEMAPHORIN 7A; UNCLASSIFIED DRUG;

EID: 84868288226     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-202952     Document Type: Review
Times cited : (17)

References (82)
  • 1
    • 0029972877 scopus 로고    scopus 로고
    • Requirement of cell interactions through adhesion molecules in the early phase of t cell development
    • Wada, K., Kina, T., Kawamoto, H., Kondo, M., and Katsura, Y. (1996) Requirement of cell interactions through adhesion molecules in the early phase of T cell development. Cell. Immunol. 170, 11-19
    • (1996) Cell. Immunol. , vol.170 , pp. 11-19
    • Wada, K.1    Kina, T.2    Kawamoto, H.3    Kondo, M.4    Katsura, Y.5
  • 2
    • 0033567976 scopus 로고    scopus 로고
    • Roles of integrins and cd44 on the adhesion and migration of fetal liver cells to the fetal thymus
    • Kawakami, N., Nishizawa, F., Sakane, N., Iwao, M., Tsujikawa, K., Ikawa, M., Okabe, M., and Yamamoto, H. (1999) Roles of integrins and CD44 on the adhesion and migration of fetal liver cells to the fetal thymus. J. Immunol. 163, 3211-3216
    • (1999) J. Immunol , vol.163 , pp. 3211-3216
    • Kawakami, N.1    Nishizawa, F.2    Sakane, N.3    Iwao, M.4    Tsujikawa, K.5    Ikawa, M.6    Okabe, M.7    Yamamoto, H.8
  • 3
    • 33750608542 scopus 로고    scopus 로고
    • Coordination between ccr7-And ccr9-mediated chemokine signals in prevascular fetal thymus colonization
    • Liu, C., Saito, F., Liu, Z., Lei, Y., Uehara, S., Love, P., Lipp, M., Kondo, S., Manley, N., and Takahama, Y. (2006) Coordination between CCR7-And CCR9-mediated chemokine signals in prevascular fetal thymus colonization. Blood 108, 2531-2539
    • (2006) Blood , vol.108 , pp. 2531-2539
    • Liu, C.1    Saito, F.2    Liu, Z.3    Lei, Y.4    Uehara, S.5    Love, P.6    Lipp, M.7    Kondo, S.8    Manley, N.9    Takahama, Y.10
  • 6
    • 65549089187 scopus 로고    scopus 로고
    • Thymic progenitor homing and lymphocyte homeostasis are linked via s1p-controlled expression of thymic p-selectin/ccl25
    • Gossens, K., Naus, S., Corbel, S. Y., Lin, S., Rossi, F. M., Kast, J., and Ziltener, H. J. (2009) Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25. J. Exp. Med. 206, 761-778
    • (2009) J. Exp. Med. , vol.206 , pp. 761-778
    • Gossens, K.1    Naus, S.2    Corbel, S.Y.3    Lin, S.4    Rossi, F.M.5    Kast, J.6    Ziltener, H.J.7
  • 7
    • 77950407764 scopus 로고    scopus 로고
    • Ccr7 and ccr9 together recruit hematopoietic progenitors to the adult thymus
    • Zlotoff, D. A., Sambandam, A., Logan, T. D., Bell, J. J., Schwarz, B. A., and Bhandoola, A. (2010) CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus. Blood 115, 1897-1905
    • (2010) Blood , vol.115 , pp. 1897-1905
    • Zlotoff, D.A.1    Sambandam, A.2    Logan, T.D.3    Bell, J.J.4    Schwarz, B.A.5    Bhandoola, A.6
  • 8
    • 77950418217 scopus 로고    scopus 로고
    • Cc chemokine receptor 7 and 9 doubledeficient hematopoietic progenitors are severely impaired in seeding the adult thymus
    • Krueger, A., Willenzon, S., Lyszkiewicz, M., Kremmer, E., and Forster, R. (2010) CC chemokine receptor 7 and 9 doubledeficient hematopoietic progenitors are severely impaired in seeding the adult thymus. Blood 115, 1906-1912
    • (2010) Blood , vol.115 , pp. 1906-1912
    • Krueger, A.1    Willenzon, S.2    Lyszkiewicz, M.3    Kremmer, E.4    Forster, R.5
  • 10
    • 70350524991 scopus 로고    scopus 로고
    • Role of dock2 and dock180 in fetal thymus colonization
    • Lei, Y., Liu, C., Saito, F., Fukui, Y., and Takahama, Y. (2009) Role of DOCK2 and DOCK180 in fetal thymus colonization. Eur. J. Immunol. 39, 2695-2702
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2695-2702
    • Lei, Y.1    Liu, C.2    Saito, F.3    Fukui, Y.4    Takahama, Y.5
  • 12
    • 0027787683 scopus 로고
    • The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules
    • Kolodkin, A. L., Matthes, D. J., and Goodman, C. S. (1993) The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules. Cell 75, 1389-1399
    • (1993) Cell , vol.75 , pp. 1389-1399
    • Kolodkin, A.L.1    Matthes, D.J.2    Goodman, C.S.3
  • 13
    • 0029037182 scopus 로고
    • Semaphorin iii can function as a selective chemorepellent to pattern sensory projections in the spinal cord
    • Messersmith, E. K., Leonardo, E. D., Shatz, C. J., Tessier-Lavigne, M., Goodman, C. S., and Kolodkin, A. L. (1995) Semaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord. Neuron 14, 949-959
    • (1995) Neuron , vol.14 , pp. 949-959
    • Messersmith, E.K.1    Leonardo, E.D.2    Shatz, C.J.3    Tessier-Lavigne, M.4    Goodman, C.S.5    Kolodkin, A.L.6
  • 14
    • 0029918439 scopus 로고    scopus 로고
    • Mechanisms and molecules that control growth cone guidance
    • Goodman, C. S. (1996) Mechanisms and molecules that control growth cone guidance. Annu. Rev. Neurosci. 19, 341-377
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 341-377
    • Goodman, C.S.1
  • 15
    • 0030724396 scopus 로고    scopus 로고
    • Brain crmp forms heterotetramers similar to liver dihydropyrimidinase
    • Wang, L. H., and Strittmatter, S. M. (1997) Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase. J. Neurochem. 69, 2261-2269
    • (1997) J. Neurochem. , Issue.69 , pp. 2261-2269
    • Wang, L.H.1    Strittmatter, S.M.2
  • 16
    • 0030929986 scopus 로고    scopus 로고
    • The eph receptor family: Axonal guidance by contact repulsion
    • Orioli, D., and Klein, R. (1997) The Eph receptor family: axonal guidance by contact repulsion. Trends Genet. 13, 354-359
    • (1997) Trends Genet. , vol.13 , pp. 354-359
    • Orioli, D.1    Klein, R.2
  • 18
    • 0348108124 scopus 로고    scopus 로고
    • Role of semaphorins in the adult nervous system
    • De Wit, J., and Verhaagen, J. (2003) Role of semaphorins in the adult nervous system. Prog. Neurobiol. 71, 249-267
    • (2003) Prog. Neurobiol. , vol.71 , pp. 249-267
    • De Wit, J.1    Verhaagen, J.2
  • 22
    • 41049099329 scopus 로고    scopus 로고
    • Neuropilin structure governs vegf and semaphorin binding and regulates angiogenesis
    • Geretti, E., Shimizu, A., and Klagsbrun, M. (2008) Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis. Angiogenesis 11, 31-39
    • (2008) Angiogenesis , vol.11 , pp. 31-39
    • Geretti, E.1    Shimizu, A.2    Klagsbrun, M.3
  • 23
    • 0036139515 scopus 로고    scopus 로고
    • The neuropilins: Multifunctional semaphorin and vegf receptors that modulate axon guidance and angiogenesis
    • Neufeld, G., Cohen, T., Shraga, N., Lange, T., Kessler, O., and Herzog, Y. (2002) The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. Trends Cardiovasc. Med. 12, 13-19
    • (2002) Trends Cardiovasc. Med. , vol.12 , pp. 13-19
    • Neufeld, G.1    Cohen, T.2    Shraga, N.3    Lange, T.4    Kessler, O.5    Herzog, Y.6
  • 24
    • 34047141776 scopus 로고    scopus 로고
    • Vascular endothelial growth factor family of ligands and receptors: Review
    • Otrock, Z. K., Makarem, J. A., and Shamseddine, A. I. (2007) Vascular endothelial growth factor family of ligands and receptors: review. Blood Cells Mol. Dis. 38, 258-268
    • (2007) Blood Cells Mol. Dis. , Issue.38 , pp. 258-268
    • Otrock, Z.K.1    Makarem, J.A.2    Shamseddine, A.I.3
  • 26
    • 84857686973 scopus 로고    scopus 로고
    • Diverse roles for semaphorin-plexin signaling in the immune system
    • Takamatsu, H., and Kumanogoh, A. (2012) Diverse roles for semaphorin-plexin signaling in the immune system. Trends Immunol. 33, 127-135
    • (2012) Trends Immunol. , Issue.33 , pp. 127-135
    • Takamatsu, H.1    Kumanogoh, A.2
  • 27
    • 41149084179 scopus 로고    scopus 로고
    • Eph-ephrin bidirectional signaling in physiology and disease
    • Pasquale, E. B. (2008) Eph-ephrin bidirectional signaling in physiology and disease. Cell 133, 38-52
    • (2008) Cell , vol.133 , pp. 38-52
    • Pasquale, E.B.1
  • 28
    • 48849108415 scopus 로고    scopus 로고
    • Eph, a protein family coming of age: More confusion, insight, or complexity?
    • Lackmann, M., and Boyd, A. W. (2008) Eph, a protein family coming of age: more confusion, insight, or complexity? Sci. Signal. 1, re2
    • (2008) Sci. Signal. , vol.1
    • Lackmann, M.1    Boyd, A.W.2
  • 33
    • 44949173024 scopus 로고    scopus 로고
    • Expression of the semaphorins sema 3d and sema 3f in the developing parathyroid and thymus
    • Takahashi, K., Ishida, M., Hirokawa, K., and Takahashi, H. (2008) Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus. Dev. Dyn. 237, 1699-1708
    • (2008) Dev. Dyn. , vol.237 , pp. 1699-1708
    • Takahashi, K.1    Ishida, M.2    Hirokawa, K.3    Takahashi, H.4
  • 39
    • 80052923989 scopus 로고    scopus 로고
    • Il-17-producing invariant nkt cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression
    • Milpied, P., Massot, B., Renand, A., Diem, S., Herbelin, A., Leite-de-Moraes, M., Rubio, M. T., and Hermine, O. (2011) IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression. Blood 118, 2993-3002
    • (2011) Blood , vol.118 , pp. 2993-3002
    • Milpied, P.1    Massot, B.2    Renand, A.3    Diem, S.4    Herbelin, A.5    Leite-de-Moraes, M.6    Rubio, M.T.7    Hermine, O.8
  • 40
    • 33746441964 scopus 로고    scopus 로고
    • Distribution of lymphatic vessels in mouse thymus: Immunofluorescence analysis
    • Odaka, C., Morisada, T., Oike, Y., and Suda, T. (2006) Distribution of lymphatic vessels in mouse thymus: immunofluorescence analysis. Cell Tissue Res. 325, 13-22
    • (2006) Cell Tissue Res. , vol.325 , pp. 13-22
    • Odaka, C.1    Morisada, T.2    Oike, Y.3    Suda, T.4
  • 43
    • 3242682356 scopus 로고    scopus 로고
    • Functional assessment of alphaebeta7/e-cadherin interactions in the steady state postnatal thymus
    • Prockop, S. E., and Petrie, H. T. (2004) Functional assessment of alphaEbeta7/E-cadherin interactions in the steady state postnatal thymus. Clin. Dev. Immunol. 11, 135-141
    • (2004) Clin. Dev. Immunol. , vol.11 , pp. 135-141
    • Prockop, S.E.1    Petrie, H.T.2
  • 45
  • 52
    • 39449085234 scopus 로고    scopus 로고
    • Eph/ephrin signaling: Networks
    • Arvanitis, D., and Davy, A. (2008) Eph/ephrin signaling: networks. Genes Dev. 22, 416-429
    • (2008) Genes Dev. , vol.22 , pp. 416-429
    • Arvanitis, D.1    Davy, A.2
  • 53
    • 0033785409 scopus 로고    scopus 로고
    • Activation of epha2 kinase suppresses integrin function and causes focal-Adhesion-kinase dephosphorylation
    • Miao, H., Burnett, E., Kinch, M., Simon, E., and Wang, B. (2000) Activation of EphA2 kinase suppresses integrin function and causes focal-Adhesion-kinase dephosphorylation. Nat. Cell Biol. 2, 62-69
    • (2000) Nat. Cell Biol. , vol.2 , pp. 62-69
    • Miao, H.1    Burnett, E.2    Kinch, M.3    Simon, E.4    Wang, B.5
  • 54
  • 55
    • 58149288204 scopus 로고    scopus 로고
    • Regulation of ephb2 activation and cell repulsion by feedback control of the mapk pathway
    • Poliakov, A., Cotrina, M. L., Pasini, A., and Wilkinson, D. G. (2008) Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway. J. Cell Biol. 183, 933-947
    • (2008) J. Cell Biol. , vol.183 , pp. 933-947
    • Poliakov, A.1    Cotrina, M.L.2    Pasini, A.3    Wilkinson, D.G.4
  • 56
    • 57649221000 scopus 로고    scopus 로고
    • Ephrin-b2-induced cleavage of ephb2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion
    • Lin, K. T., Sloniowski, S., Ethell, D. W., and Ethell, I. M. (2008) Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion. J. Biol. Chem. 283, 28969-28979
    • (2008) J. Biol. Chem. , Issue.283 , pp. 28969-28979
    • Lin, K.T.1    Sloniowski, S.2    Ethell, D.W.3    Ethell, I.M.4
  • 58
    • 0344305470 scopus 로고    scopus 로고
    • Human dendritic cells express neuronal eph receptor tyrosine kinases: Role of epha2 in regulating adhesion to fibronectin
    • De Saint-Vis, B., Bouchet, C., Gautier, G., Valladeau, J., Caux, C., and Garrone, P. (2003) Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin. Blood 102, 4431-4440
    • (2003) Blood , vol.102 , pp. 4431-4440
    • De Saint-Vis, B.1    Bouchet, C.2    Gautier, G.3    Valladeau, J.4    Caux, C.5    Garrone, P.6
  • 59
    • 60449108489 scopus 로고    scopus 로고
    • Receptor tyrosine kinase epha2 mediates thrombin-induced upregulation of icam-1 in endothelial cells in vitro
    • Chan, B., and Sukhatme, V. P. (2009) Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro. Thromb. Res. 123, 745-752
    • (2009) Thromb. Res. , vol.123 , pp. 745-752
    • Chan, B.1    Sukhatme, V.P.2
  • 60
    • 33745684086 scopus 로고    scopus 로고
    • Putative dual role of ephrin-eph receptor interactions in inflammation
    • Ivanov, A. I., and Romanovsky, A. A. (2006) Putative dual role of ephrin-Eph receptor interactions in inflammation. IUBMB Life 58, 389-394
    • (2006) IUBMB Life , vol.58 , pp. 389-394
    • Ivanov, A.I.1    Romanovsky, A.A.2
  • 61
    • 15944420186 scopus 로고    scopus 로고
    • Ephrin-A1 binding to cd4-t lymphocytes stimulates migration and induces tyrosine phosphorylation of pyk2
    • Aasheim, H. C., Delabie, J., and Finne, E. F. (2005) Ephrin-A1 binding to CD4-T lymphocytes stimulates migration and induces tyrosine phosphorylation of PYK2. Blood 105, 2869-2876
    • (2005) Blood , vol.105 , pp. 2869-2876
    • Aasheim, H.C.1    Delabie, J.2    Finne, E.F.3
  • 62
    • 67650474952 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis interferes with the response to infection by inducing the host epha2 receptor
    • Khounlotham, M., Subbian, S., Smith, R., 3rd, Cirillo, S. L., and Cirillo, J. D. (2009) Mycobacterium tuberculosis interferes with the response to infection by inducing the host EphA2 receptor. J. Infect. Dis. 199, 1797-1806
    • (2009) J. Infect. Dis. , vol.199 , pp. 1797-1806
    • Khounlotham, M.1    Subbian, S.2    Smith III, R.3    Cirillo, S.L.4    Cirillo, J.D.5
  • 65
    • 73949090085 scopus 로고    scopus 로고
    • An impaired transendothelial migration potential of chronic lymphocytic leukemia (cll) cells can be linked to ephrin-A4 expression
    • Trinidad, E. M., Ballesteros, M., Zuloaga, J., Zapata, A., and Alonso-Colmenar, L. M. (2009) An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression. Blood 114, 5081-5090
    • (2009) Blood , vol.114 , pp. 5081-5090
    • Trinidad, E.M.1    Ballesteros, M.2    Zuloaga, J.3    Zapata, A.4    Alonso-Colmenar, L.M.5
  • 66
    • 77956478918 scopus 로고    scopus 로고
    • Eph-ephrin bidirectional signaling comes into the context of lymphocyte transendothelial migration
    • Trinidad, E. M., Zapata, A. G., and Alonso-Colmenar, L. M. (2010) Eph-ephrin bidirectional signaling comes into the context of lymphocyte transendothelial migration. Cell. Adh. Migr. 4, 363-367
    • (2010) Cell. Adh. Migr. , Issue.4 , pp. 363-367
    • Trinidad, E.M.1    Zapata, A.G.2    Alonso-Colmenar, L.M.3
  • 67
    • 58549092027 scopus 로고    scopus 로고
    • Expression profile of eph receptors and ephrin ligands in healthy human b lymphocytes and chronic lymphocytic leukemia b-cells
    • Alonso, C. L., Trinidad, E. M., de Garcillan, B., Ballesteros, M., Castellanos, M., Cotillo, I., Munoz, J. J., and Zapata, A. G. (2009) Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells. Leuk. Res. 33, 395-406
    • (2009) Leuk. Res. , vol.33 , pp. 395-406
    • Alonso, C.L.1    Trinidad, E.M.2    De Garcillan, B.3    Ballesteros, M.4    Castellanos, M.5    Cotillo, I.6    Munoz, J.J.7    Zapata, A.G.8
  • 68
    • 84855338916 scopus 로고    scopus 로고
    • Inhibitory effect of semaphorin-3a, a known axon guidance molecule, in the human thymocyte migration induced by cxcl12
    • Garcia, F., Lepelletier, Y., Smaniotto, S., Hadj-Slimane, R., Dardenne, M., Hermine, O., Savino, W. (2012) Inhibitory effect of semaphorin-3A, a known axon guidance molecule, in the human thymocyte migration induced by CXCL12. J. Leukocyte Biol. 91, 7-13
    • (2012) J. Leukocyte Biol. , Issue.91 , pp. 7-13
    • Garcia, F.1    Lepelletier, Y.2    Smaniotto, S.3    Hadj-Slimane, R.4    Dardenne, M.5    Hermine, O.6    Savino, W.7
  • 69
    • 77955768603 scopus 로고    scopus 로고
    • P75ntr is an obligate signaling receptor required for cues that cause sympathetic neuron growth cone collapse
    • Naska, S., Lin, D. C., Miller, F. D., and Kaplan, D. R. (2010) p75NTR is an obligate signaling receptor required for cues that cause sympathetic neuron growth cone collapse. Mol. Cell. Neurosci. 45, 108-120
    • (2010) Mol. Cell. Neurosci. , Issue.45 , pp. 108-120
    • Naska, S.1    Lin, D.C.2    Miller, F.D.3    Kaplan, D.R.4
  • 70
    • 1642382128 scopus 로고    scopus 로고
    • Integration of semaphorin-2a/mab-20, ephrin-4, and unc-129 tgf-beta signaling pathways regulates sorting of distinct sensory rays in c. Elegans
    • Ikegami, R., Zheng, H., Ong, S. H., and Culotti, J. (2004) Integration of semaphorin-2A/MAB-20, ephrin-4, and UNC-129 TGF-beta signaling pathways regulates sorting of distinct sensory rays in C. elegans. Dev. Cell. 6, 383-395
    • (2004) Dev. Cell. , vol.6 , pp. 383-395
    • Ikegami, R.1    Zheng, H.2    Ong, S.H.3    Culotti, J.4
  • 74
    • 71749104649 scopus 로고    scopus 로고
    • Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes
    • Ehrlich, L. I., Oh, D. Y., Weissman, I. L., and Lewis, R. S. (2009) Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes. Immunity 31, 986-998
    • (2009) Immunity , vol.31 , pp. 986-998
    • Ehrlich, L.I.1    Oh, D.Y.2    Weissman, I.L.3    Lewis, R.S.4
  • 75
    • 33646021339 scopus 로고    scopus 로고
    • Epha receptors inhibit anti-cd3-induced apoptosis in thymocytes
    • Freywald, A., Sharfe, N., Miller, C. D., Rashotte, C., and Roifman, C. M. (2006) EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes. J. Immunol. 176, 4066-4074
    • (2006) J. Immunol. , Issue.176 , pp. 4066-4074
    • Freywald, A.1    Sharfe, N.2    Miller, C.D.3    Rashotte, C.4    Roifman, C.M.5
  • 77
    • 0032143862 scopus 로고    scopus 로고
    • New eukaryotic semaphorins with close homology to semaphorins of dna viruses
    • Lange, C., Liehr, T., Goen, M., Gebhart, E., Fleckenstein, B., and Ensser, A. (1998) New eukaryotic semaphorins with close homology to semaphorins of DNA viruses. Genomics 51, 340-350
    • (1998) Genomics , vol.51 , pp. 340-350
    • Lange, C.1    Liehr, T.2    Goen, M.3    Gebhart, E.4    Fleckenstein, B.5    Ensser, A.6
  • 80
    • 49249138982 scopus 로고    scopus 로고
    • Alterations in the thymocyte phenotype of ephb-deficient mice largely affect the double negative cell compartment
    • Alfaro, D., Munoz, J. J., Garcia-Ceca, J., Cejalvo, T., Jimenez, E., and Zapata, A. (2008) Alterations in the thymocyte phenotype of EphB-deficient mice largely affect the double negative cell compartment. Immunology 125, 131-143
    • (2008) Immunology , vol.125 , pp. 131-143
    • Alfaro, D.1    Munoz, J.J.2    Garcia-Ceca, J.3    Cejalvo, T.4    Jimenez, E.5    Zapata, A.6
  • 81
    • 0038324016 scopus 로고    scopus 로고
    • The ephb6 receptor inhibits jnk activation in t lymphocytes and modulates t cell receptormediated responses
    • Freywald, A., Sharfe, N., Rashotte, C., Grunberger, T., and Roifman, C. M. (2003) The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptormediated responses. J. Biol. Chem. 278, 10150-10156
    • (2003) J. Biol. Chem. , Issue.278 , pp. 10150-10156
    • Freywald, A.1    Sharfe, N.2    Rashotte, C.3    Grunberger, T.4    Roifman, C.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.