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Volumn 2012, Issue , 2012, Pages

The putative role of the antiageing protein Klotho in cardiovascular and renal disease

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; KLOTHO PROTEIN; NITRIC OXIDE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84868280201     PISSN: 20900384     EISSN: 20900392     Source Type: Journal    
DOI: 10.1155/2012/757469     Document Type: Review
Times cited : (33)

References (41)
  • 1
    • 0034626774 scopus 로고    scopus 로고
    • Why do we age?
    • 2-s2.0-0034626774 10.1038/35041682
    • Kirkwood T. B. L., Austad S. N., Why do we age? Nature 2000 408 6809 233 238 2-s2.0-0034626774 10.1038/35041682
    • (2000) Nature , vol.408 , Issue.6809 , pp. 233-238
    • Kirkwood, T.B.L.1    Austad, S.N.2
  • 2
    • 0032490711 scopus 로고    scopus 로고
    • Endothelial function in health and disease: New insights into the genesis of cardiovascular disease
    • 2-s2.0-0032490711
    • Quyyumi A. A., Endothelial function in health and disease: new insights into the genesis of cardiovascular disease. American Journal of Medicine 1998 105 1 A 2-s2.0-0032490711
    • (1998) American Journal of Medicine , vol.105 , Issue.1 A
    • Quyyumi, A.A.1
  • 3
    • 41649116606 scopus 로고    scopus 로고
    • Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction
    • DOI 10.1080/07853890701854702, PII 790575153
    • Münzel T., Sinning C., Post F., Warnholtz A., Schulz E., Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction. Annals of Medicine 2008 40 3 180 196 2-s2.0-41649116606 10.1080/07853890701854702 (Pubitemid 351482543)
    • (2008) Annals of Medicine , vol.40 , Issue.3 , pp. 180-196
    • Munzel, T.1    Sinning, C.2    Post, F.3    Warnholtz, A.4    Schulz, E.5
  • 4
    • 0037469206 scopus 로고    scopus 로고
    • Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises. Part III: Cellular and molecular clues to heart and arterial aging
    • DOI 10.1161/01.CIR.0000048894.99865.02
    • Lakatta E. G., Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises. Part III: cellular and molecular clues to heart and arterial aging. Circulation 2003 107 3 490 497 2-s2.0-0037469206 10.1161/01.CIR.0000048894.99865.02 (Pubitemid 36158054)
    • (2003) Circulation , vol.107 , Issue.3 , pp. 490-497
    • Lakatta, E.G.1
  • 5
    • 79955035385 scopus 로고    scopus 로고
    • Signalling pathways and vascular calcification
    • 10.2741/3790
    • Liu Y., Shanahan C. M., cathy.shanahan@kcl.ac.uk Signalling pathways and vascular calcification. Frontiers in Bioscience 2011 16 4 1302 1314 10.2741/3790
    • (2011) Frontiers in Bioscience , vol.16 , Issue.4 , pp. 1302-1314
    • Liu, Y.1    Shanahan, C.M.2
  • 7
    • 0032567647 scopus 로고    scopus 로고
    • Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein
    • DOI 10.1006/bbrc.1997.8019
    • Matsumura Y., Aizawa H., Shiraki-Iida T., Nagai R., Kuro-o M., Nabeshima Y. I., Identification of the human Klotho gene and its two transcripts encoding membrane and secreted Klotho protein. Biochemical and Biophysical Research Communications 1998 242 3 626 630 2-s2.0-0032567647 10.1006/bbrc.1997.8019 (Pubitemid 28412578)
    • (1998) Biochemical and Biophysical Research Communications , vol.242 , Issue.3 , pp. 626-630
    • Matsumura, Y.1    Aizawa, H.2    Shiraki-Iida, T.3    Nagai, R.4    Kuro-O, M.5    Nabeshima, Y.-I.6
  • 10
    • 33748090908 scopus 로고    scopus 로고
    • Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolism
    • DOI 10.1097/01.mnh.0000232885.81142.83, PII 0004155220060700000013
    • Kuro-o M., Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolism. Current Opinion in Nephrology and Hypertension 2006 15 4 437 441 2-s2.0-33748090908 10.1097/01.mnh.0000232885.81142.83 (Pubitemid 44297987)
    • (2006) Current Opinion in Nephrology and Hypertension , vol.15 , Issue.4 , pp. 437-441
    • Kuro-o, M.1
  • 11
    • 33845631059 scopus 로고    scopus 로고
    • Klotho converts canonical FGF receptor into a specific receptor for FGF23
    • DOI 10.1038/nature05315, PII NATURE05315
    • Urakawa I., Yamazaki Y., Shimada T., Iijima K., Hasegawa H., Okawa K., Fujita T., Fukumoto S., Yamashita T., Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 2006 444 7120 770 774 2-s2.0-33845631059 10.1038/nature05315 (Pubitemid 44949607)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 770-774
    • Urakawa, I.1    Yamazaki, Y.2    Shimada, T.3    Iijima, K.4    Hasegawa, H.5    Okawa, K.6    Fujita, T.7    Fukumoto, S.8    Yamashita, T.9
  • 12
  • 13
    • 33646238028 scopus 로고    scopus 로고
    • Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process
    • DOI 10.1096/fj.05-5432fje
    • Razzaque M. S., Sitara D., Taguchi T., St-Arnaud R., Lanske B., Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. The FASEB Journal 2006 20 6 720 722 2-s2.0-33646238028 10.1096/fj.05-5432fje (Pubitemid 46671193)
    • (2006) FASEB Journal , vol.20 , Issue.6 , pp. 720-722
    • Razzaque, M.S.1    Sitara, D.2    Taguchi, T.3    St-Arnaud, R.4    Lanske, B.5
  • 14
    • 34250667000 scopus 로고    scopus 로고
    • Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice
    • DOI 10.1681/ASN.2006121385
    • Stubbs J. R., Liu S., Tang W., Zhou J., Wang Y., Yao X., Quarles L. D., Role of hyperphosphatemia and 1,25-dihydroxyvitamin D in vascular calcification and mortality in fibroblastic growth factor 23 null mice. Journal of the American Society of Nephrology 2007 18 7 2116 2124 2-s2.0-34250667000 10.1681/ASN.2006121385 (Pubitemid 47041077)
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.7 , pp. 2116-2124
    • Stubbs, J.R.1    Liu, S.2    Tang, W.3    Zhou, J.4    Wang, Y.5    Yao, X.6    Quarles, L.D.7
  • 16
    • 27744545673 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease
    • DOI 10.1681/ASN.2005010052
    • Gutierrez O., Isakova T., Rhee E., Shah A., Holmes J., Collerone G., Jüppner H., Wolf M., Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease. Journal of the American Society of Nephrology 2005 16 7 2205 2215 2-s2.0-27744545673 10.1681/ASN.2005010052 (Pubitemid 41716454)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.7 , pp. 2205-2215
    • Gutierrez, O.1    Isakova, T.2    Rhee, E.3    Shah, A.4    Holmes, J.5    Collerone, G.6    Juppner, H.7    Wolf, M.8
  • 18
    • 69249106380 scopus 로고    scopus 로고
    • High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients
    • 2-s2.0-69249106380 10.1093/ndt/gfp191
    • Jean G., Terrat J. C., Vanel T., Hurot J. M., Lorriaux C., Mayor B., Chazot C., High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients. Nephrology Dialysis Transplantation 2009 24 9 2792 2796 2-s2.0-69249106380 10.1093/ndt/gfp191
    • (2009) Nephrology Dialysis Transplantation , vol.24 , Issue.9 , pp. 2792-2796
    • Jean, G.1    Terrat, J.C.2    Vanel, T.3    Hurot, J.M.4    Lorriaux, C.5    Mayor, B.6    Chazot, C.7
  • 19
    • 65649129465 scopus 로고    scopus 로고
    • FGF23-mediated regulation of systemic phosphate homeostasis: Is Klotho an essential player?
    • 2-s2.0-65649129465 10.1152/ajprenal.90538.2008
    • Razzaque M. S., FGF23-mediated regulation of systemic phosphate homeostasis: is Klotho an essential player? American Journal of Physiology 2009 296 3 F470 F476 2-s2.0-65649129465 10.1152/ajprenal.90538.2008
    • (2009) American Journal of Physiology , vol.296 , Issue.3
    • Razzaque, M.S.1
  • 21
    • 80655141616 scopus 로고    scopus 로고
    • Aging-related kidney damage is associated with a decrease in Klotho expression and an increase in superoxide production
    • 2-s2.0-77956328818 10.1007/s11357-010-9176-2
    • Zuo Z., Lei H., Wang X., Wang Y., Sonntag W., Sun Z., Aging-related kidney damage is associated with a decrease in Klotho expression and an increase in superoxide production. Age 2010 1 14 2-s2.0-77956328818 10.1007/s11357-010- 9176-2
    • (2010) Age , pp. 1-14
    • Zuo, Z.1    Lei, H.2    Wang, X.3    Wang, Y.4    Sonntag, W.5    Sun, Z.6
  • 22
    • 79956321007 scopus 로고    scopus 로고
    • Circulating levels of soluble alpha-Klotho are markedly elevated in human umbilical cord blood
    • Ohata Y., Arahori H., Namba N., Circulating levels of soluble alpha-Klotho are markedly elevated in human umbilical cord blood. Journal of Clinical Endocrinology Metabolism 2011 96 E943 E947
    • (2011) Journal of Clinical Endocrinology Metabolism , vol.96
    • Ohata, Y.1    Arahori, H.2    Namba, N.3
  • 23
    • 80051518025 scopus 로고    scopus 로고
    • Plasma Klotho and mortality risk in older community-dwelling adults
    • Semba R. D., Cappola A. R., Sun K., Plasma Klotho and mortality risk in older community-dwelling adults. The Journal of Gerontology Series A 2011 66 794 800
    • (2011) The Journal of Gerontology Series A , vol.66 , pp. 794-800
    • Semba, R.D.1    Cappola, A.R.2    Sun, K.3
  • 26
    • 23944483457 scopus 로고    scopus 로고
    • Oxidative stress decreases klotho expression in a mouse kidney cell line
    • DOI 10.1159/000086500
    • Mitobe M., Yoshida T., Sugiura H., Shirota S., Tsuchiya K., Nihei H., Oxidative stress decreases Klotho expression in a mouse kidney cell line. Nephron Experimental Nephrology 2005 101 2 e67 e74 2-s2.0-23944483457 10.1159/000086500 (Pubitemid 41208903)
    • (2005) Nephron - Experimental Nephrology , vol.101 , Issue.2
    • Mitobe, M.1    Yoshida, T.2    Sugiura, H.3    Shirota, S.4    Tsuchiya, K.5    Nihei, H.6
  • 28
    • 78649642147 scopus 로고    scopus 로고
    • Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective
    • 2-s2.0-78649642147 10.1038/ki.2010.328
    • Hu M. C., Shi M., Zhang J., Quiones H., Kuro-o M., Moe O. W., Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective. Kidney International 2010 78 12 1240 1251 2-s2.0-78649642147 10.1038/ki.2010.328
    • (2010) Kidney International , vol.78 , Issue.12 , pp. 1240-1251
    • Hu, M.C.1    Shi, M.2    Zhang, J.3    Quiones, H.4    Kuro-O, M.5    Moe, O.W.6
  • 32
    • 70349659193 scopus 로고    scopus 로고
    • Klotho gene delivery prevents the progression of spontaneous hypertension and renal damage
    • 2-s2.0-70349659193 10.1161/HYPERTENSIONAHA.109.134320
    • Wang Y., Sun Z., Klotho gene delivery prevents the progression of spontaneous hypertension and renal damage. Hypertension 2009 54 4 810 817 2-s2.0-70349659193 10.1161/HYPERTENSIONAHA.109.134320
    • (2009) Hypertension , vol.54 , Issue.4 , pp. 810-817
    • Wang, Y.1    Sun, Z.2
  • 34
    • 79953138206 scopus 로고    scopus 로고
    • Klotho inhibits transforming growth factor- β 1 (TGF- β 1) signaling and suppresses renal fibrosis and cancer metastasis in mice
    • 10.1074/jbc.M110.174037
    • Doi S., Zou Y., Togao O., Pastor J. V., John G. B., Wang L., Shiizaki K., Gotschall R., Schiavi S., Yorioka N., Takahashi M., Boothman D. A., david.boothman@utsouthwestern.edu Kuro-o M., makoto.kuro-o@utsouthwestern.edu Klotho inhibits transforming growth factor- β 1 (TGF- β 1) signaling and suppresses renal fibrosis and cancer metastasis in mice. Journal of Biological Chemistry 2011 286 10 8655 8665 10.1074/jbc.M110.174037
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.10 , pp. 8655-8665
    • Doi, S.1    Zou, Y.2    Togao, O.3    Pastor, J.V.4    John, G.B.5    Wang, L.6    Shiizaki, K.7    Gotschall, R.8    Schiavi, S.9    Yorioka, N.10    Takahashi, M.11    Boothman, D.A.12
  • 36
    • 78651408919 scopus 로고    scopus 로고
    • Klotho deficiency causes vascular calcification in chronic kidney disease
    • Hu M. C., Shi M., Zhang J., Klotho deficiency causes vascular calcification in chronic kidney disease. Journal of the American Society of Nephrology 2011 22 124 136
    • (2011) Journal of the American Society of Nephrology , vol.22 , pp. 124-136
    • Hu, M.C.1    Shi, M.2    Zhang, J.3
  • 38
    • 0034130405 scopus 로고    scopus 로고
    • Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases
    • DOI 10.1007/s000180050038
    • Nagai R., Saito Y., Ohyama Y., Aizawa H., Suga T., Nakamura T., Kurabayashi M., Kuro-o M., Endothelial dysfunction in the Klotho mouse and downregulation of Klotho gene expression in various animal models of vascular and metabolic diseases. Cellular and Molecular Life Sciences 2000 57 5 738 746 2-s2.0-0034130405 10.1007/s000180050038 (Pubitemid 30392032)
    • (2000) Cellular and Molecular Life Sciences , vol.57 , Issue.5 , pp. 738-746
    • Nagai, R.1    Saito, Y.2    Ohyama, Y.3    Aizawa, H.4    Suga, T.5    Nakamura, T.6    Kurabayashi, M.7    Kuro-O, M.8
  • 41
    • 70149098681 scopus 로고    scopus 로고
    • Klotho suppresses TNF- α -induced expression of adhesion molecules in the endothelium and attenuates NF- κ B activation
    • 2-s2.0-70149098681 10.1007/s12020-009-9181-3
    • Maekawa Y., Ishikawa K., Yasuda O., Oguro R., Hanasaki H., Kida I., Takemura Y., Ohishi M., Katsuya T., Rakugi H., Klotho suppresses TNF- α -induced expression of adhesion molecules in the endothelium and attenuates NF- κ B activation. Endocrine 2009 35 3 341 346 2-s2.0-70149098681 10.1007/s12020-009-9181-3
    • (2009) Endocrine , vol.35 , Issue.3 , pp. 341-346
    • Maekawa, Y.1    Ishikawa, K.2    Yasuda, O.3    Oguro, R.4    Hanasaki, H.5    Kida, I.6    Takemura, Y.7    Ohishi, M.8    Katsuya, T.9    Rakugi, H.10


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