Novel peptidomimetic compounds containing redox active chalcogens and quinones as potential anticancer agents

European Journal of Medicinal Chemistry

Volumn 58, Issue , 2012, Pages 192-205

  Shaaban, Saad ^a,c   Diestel, Randi ^a   Hinkelmann, Bettina ^a   Muthukumar, Yazh ^a   Verma, Rajeshwar P ^b   Sasse, Florenz ^a   Jacob, Claus ^c  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b POMONA COLLEGE   (United States)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Anticancer activity; Chemogenomic assay; Multicomponent reactions; Oxidative stress; Passerini reaction

Indexed keywords

ANTINEOPLASTIC AGENT; CHALCOGEN; GLUTATHIONE; PEPTIDOMIMETIC AGENT; QUINONE DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER CELL; CATALYST; CELL CYCLE ARREST; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULE; OXIDATIVE STRESS; SYNTHESIS;

ANTINEOPLASTIC AGENTS; BIOMIMETIC MATERIALS; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHALCOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PEPTIDES; QUINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84868253564     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.09.033     Document Type: Article

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