In vitro inhibition of SKOV-3 cell migration as a distinctive feature of progesterone receptor membrane component type 2 versus type 1

Steroids

Volumn 77, Issue 14, 2012, Pages 1543-1550

  Albrecht, Christian ^a   Huck, Volker ^a   Wehling, Martin ^a   Wendler, Alexandra ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cytochrome P450; Interaction; Migration; Ovarian cancer; PGRMC2

Indexed keywords

CISPLATIN; CYTOCHROME P450; CYTOCHROME P450 3A4; F ACTIN; PROGESTERONE RECEPTOR; PROGESTERONE RECEPTOR MEMBRANE COMPONENT TYPE 1; PROGESTERONE RECEPTOR MEMBRANE COMPONENT TYPE 2; UNCLASSIFIED DRUG;

ACTIN FILAMENT; APOPTOSIS; ARTICLE; CANCER CELL; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO CELL; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; IMPEDANCE; IN VITRO STUDY; KIDNEY CELL; OVARY CANCER; PROTEIN DEPLETION; PROTEIN EXPRESSION; VELOCITY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CISPLATIN; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; OVARIAN NEOPLASMS; RECEPTORS, PROGESTERONE;

EID: 84868241331     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.09.006     Document Type: Article

References (42)

1. D. Gerdes, M. Wehling, B. Leube, and E. Falkenstein Cloning and tissue expression of two putative steroid membrane receptors Biol Chem 379 1998 907 911
2. Mifsud W, Bateman A. Membrane-bound progesterone receptors contain a cytochrome b5-like ligand-binding domain. Genome Biol 2002; 3: RESEARCH0068.
3. C. Meyer, K. Schmieding, E. Falkenstein, and M. Wehling Are high-affinity progesterone binding site(s) from porcine liver microsomes members of the sigma receptor family? Eur J Pharmacol 347 1998 293 299
4. J. Xu, C. Zeng, W. Chu, F. Pan, J.M. Rothfuss, and F. Zhang Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site Nat Commun 2 2011 380
5. G. Crudden, R. Loesel, and R.J. Craven Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors Tumour Biol 26 2005 142 146
6. J.J. Peluso, X. Liu, M.M. Saunders, K.P. Claffey, and K. Phoenix Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1 J Clin Endocrinol Metab 93 2008 1592 1599
7. G. Crudden, R.E. Chitti, and R.J. Craven Hpr6 (heme-1 domain protein) regulates the susceptibility of cancer cells to chemotherapeutic drugs J Pharmacol Exp Ther 316 2006 448 455
8. J.J. Peluso, A. Pappalardo, R. Losel, and M. Wehling Progesterone membrane receptor component 1 expression in the immature rat ovary and its role in mediating progesterone's antiapoptotic action Endocrinology 147 2006 3133 3140
9. J.J. Peluso, J. Romak, and X. Liu Progesterone receptor membrane component-1 (PGRMC1) is the mediator of progesterone's antiapoptotic action in spontaneously immortalized granulosa cells as revealed by PGRMC1 small interfering ribonucleic acid treatment and functional analysis of PGRMC1 mutations Endocrinology 149 2008 534 543
10. H.J. Rohe, I.S. Ahmed, K.E. Twist, and R.J. Craven PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding Pharmacol Ther 121 2009 14 19
11. E. Szczesna-Skorupa, and B. Kemper Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductase Mol Pharmacol 79 2011 340 350
12. S. Oda, M. Nakajima, Y. Toyoda, T. Fukami, and T. Yokoi Progesterone receptor membrane component 1 modulates human cytochrome p450 activities in an isoform-dependent manner Drug Metab Dispos 39 2011 2057 2065
13. R. Losel, S. Breiter, M. Seyfert, M. Wehling, and E. Falkenstein Classic and non-classic progesterone receptors are both expressed in human spermatozoa Horm Metab Res 37 2005 10 14
14. L. Zhang, Y. Kanda, D.J. Roberts, J.L. Ecker, R. Losel, and M. Wehling Expression of progesterone receptor membrane component 1 and its partner serpine 1 mRNA binding protein in uterine and placental tissues of the mouse and human Mol Cell Endocrinol 287 2008 81 89
15. R. Shankar, M.P. Johnson, N.A. Williamson, F. Cullinane, A.W. Purcell, and E.K. Moses Molecular markers of preterm labor in the choriodecidua Reprod Sci 17 2010 297 310
16. Y. Hirai, K. Utsugi, N. Takeshima, Y. Kawamata, R. Furuta, and T. Kitagawa Putative gene loci associated with carcinogenesis and metastasis of endocervical adenocarcinomas of uterus determined by conventional and array-based CGH Am J Obstet Gynecol 191 2004 1173 1182
17. M.W. Causey, L.J. Huston, D.M. Harold, C.J. Charaba, D.L. Ippolito, and Z.S. Hoffer Transcriptional Analysis of Novel Hormone Receptors PGRMC1 and PGRMC2 as Potential Biomarkers of Breast Adenocarcinoma Staging J Surg Res 171 2010 615 622
18. I.S. Ahmed, H.J. Rohe, K.E. Twist, M.N. Mattingly, and R.J. Craven Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule J Pharmacol Exp Ther 333 2010 564 573
19. J.J. Peluso, X. Liu, A. Gawkowska, V. Lodde, and C.A. Wu Progesterone inhibits apoptosis in part by PGRMC1-regulated gene expression Mol Cell Endocrinol 320 2010 153 161
20. J.J. Peluso Non-genomic actions of progesterone in the normal and neoplastic mammalian ovary Semin Reprod Med 25 2007 198 207
21. I. Nolte, D. Jeckel, F.T. Wieland, and K. Sohn Localization and topology of ratp28, a member of a novel family of putative steroid-binding proteins Biochim Biophys Acta 1543 2000 123 130
22. R.A. Hand, and R.J. Craven Hpr6.6 protein mediates cell death from oxidative damage in MCF-7 human breast cancer cells J Cell Biochem 90 2003 534 547
23. L. Min, N.V. Strushkevich, I.N. Harnastai, H. Iwamoto, A.A. Gilep, and H. Takemori Molecular identification of adrenal inner zone antigen as a heme-binding protein FEBS J 272 2005 5832 5843
24. H. Sakamoto, K. Ukena, H. Takemori, M. Okamoto, M. Kawata, and K. Tsutsui Expression and localization of 25-Dx, a membrane-associated putative progesterone-binding protein, in the developing Purkinje cell Neuroscience 126 2004 325 334
25. A.L. Hughes, D.W. Powell, M. Bard, J. Eckstein, R. Barbuch, and A.J. Link Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes Cell Metab 5 2007 143 149
26. J.J. Peluso, X. Liu, A. Gawkowska, and E. Johnston-MacAnanny Progesterone activates a progesterone receptor membrane component 1-dependent mechanism that promotes human granulosa/luteal cell survival but not progesterone secretion J Clin Endocrinol Metab 94 2009 2644 2649
27. Bravo-Cordero JJ, Hodgson L, Condeelis J. Directed cell invasion and migration during metastasis. Curr Opin Cell Biol. 2011.
28. Y. Gavrieli, Y. Sherman, and S.A. Ben-Sasson Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J Cell Biol 119 1992 493 501
29. T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 1983 55 63
30. H.J. Jung, J.Y. Park, H.S. Jeon, and T.H. Kwon Aquaporin-5: a marker protein for proliferation and migration of human breast cancer cells PLoS One 6 2011 e28492
31. F. Zhao, M.K. Siu, L. Jiang, K.F. Tam, H.Y. Ngan, and X.F. Le Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival Histopathology 59 2011 1163 1172
32. Tan HT, Wei W, Ng YZ, Zhang X, Yan B, Ong CW, et al. Proteomic Analysis of Colorectal Cancer Metastasis: Stathmin-1 Revealed as a Player in Cancer Cell Migration and Prognostic Marker. J Proteome Res 2011.
33. Kawamura M, Toiyama Y, Tanaka K, Saigusa S, Okugawa Y, Hiro J, et al. CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer. Eur J Cancer 2011.
34. C. Ballestrem, B. Wehrle-Haller, and B.A. Imhof Actin dynamics in living mammalian cells J Cell Sci 111 Pt 12 1998 1649 1658
35. E.A. Papakonstanti, and C. Stournaras Cell responses regulated by early reorganization of actin cytoskeleton FEBS Lett 582 2008 2120 2127
36. W. Wang, S. Goswami, K. Lapidus, A.L. Wells, J.B. Wyckoff, and E. Sahai Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors Cancer Res 64 2004 8585 8594
37. W. Wang, J.B. Wyckoff, S. Goswami, Y. Wang, M. Sidani, and J.E. Segall Coordinated regulation of pathways for enhanced cell motility and chemotaxis is conserved in rat and mouse mammary tumors Cancer Res 67 2007 3505 3511
38. R.A. Debose-Boyd A helping hand for cytochrome p450 enzymes Cell Metab 5 2007 81 83
39. J.J. Peluso, A. Gawkowska, X. Liu, T. Shioda, and J.K. Pru Progesterone receptor membrane component-1 regulates the development and cisplatin sensitivity of human ovarian tumors in athymic nude mice Endocrinology 150 2009 4846 4854
40. N. Zhang, Z.M. Wu, E. McGowan, J. Shi, Z.B. Hong, and C.W. Ding Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: therapeutic potential for ovarian cancer Cancer Sci 100 2009 2459 2464
41. J.A. Smith, H. Ngo, M.C. Martin, and J.K. Wolf An evaluation of cytotoxicity of the taxane and platinum agents combination treatment in a panel of human ovarian carcinoma cell lines Gynecol Oncol 98 2005 141 145
42. S. Mabuchi, D.A. Altomare, M. Cheung, L. Zhang, P.I. Poulikakos, and H.H. Hensley RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model Clin. Cancer Res. 13 2007 4261 4270