Hpr6.6 Protein mediates cell death from oxidative damage in MCF-7 human breast cancer cells

Journal of Cellular Biochemistry

Volumn 90, Issue 3, 2003, Pages 534-547

  Hand, Randal A ^a   Craven, Rolf J ^b,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Breast cancer; Cell death; Oxidative damage; Proliferation; Signaling

Indexed keywords

HYDROGEN PEROXIDE; MEMBRANE RECEPTOR; PHOSPHOTRANSFERASE; PROGESTERONE BINDING PROTEIN; PROTEIN DAP1P; PROTEIN HPR6.6; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER; CANCER CELL; CELL DEATH; DEGENERATION; EPITHELIUM; HUMAN; HUMAN CELL; INFECTION; INJURY; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BREAST NEOPLASMS; CELL DEATH; CLONING, MOLECULAR; ENTEROTOXINS; FEMALE; HUMANS; HYDROGEN PEROXIDE; I-KAPPA B KINASE; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; RECEPTORS, PROGESTERONE; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

MINK CELL FOCUS-FORMING VIRUS; SACCHAROMYCETALES;

EID: 0141919706     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.10648     Document Type: Article

References (40)

1. Aoki M, Nata T, Morishita R, Matsushita H, Nakagami H, Yamamoto K, Yamazaki K, Nakabayashi M, Ogihara T, Kaneda Y. 2001. Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: Anti-apoptotic effect of antioxidant agents on endothelial cells. Hypertension 38:48-55.
2. Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U. 1995. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 267:1484-1488.
3. Cadenas E, Davies KJA. 2000. Mitochondrial free radical generation, oxidative stress, and aging. Free Rad Biol Med 29:222-230.
4. Cance WG, Craven RJ, Bergman M, Xu L, Alitalo K, Liu ET. 1994. Rak, a novel nuclear tyrosine kinase expressed in epithelial cells. Cell Growth Differ 5:1347-1355.
5. Cantley LC. 2002. The phosphoinositide 3-kinase pathway. Science 296:1655-1657.
6. Clemens JA, Stephenson DT, Yin T, Smalstig EB, Panetta JA, Little SP. 1997. Drug-induced neoroprotection from global ischemia is associated with prevention of persistent but not transient activation of nuclear factor-κB in rats. Stroke 29:677-682.
7. Gasch AP, Huang M, Metzner S, Botstein D, Elledge SJ, Brown PO. 2001. Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol Biol Cell 12:2987-3003.
8. Gerdes D, Wehling M, Leube B, Falkenstein E. 1998. Cloning and tissue expression of two putative steroid membrane receptors. Biol Chem 379:907-911.
9. Gniedecki R, Christoffersen N, Wulf HC. 2002. Cholesterol-rich plasma membrane domains (lipid rafts) in keratinocytes: importance of the baseline and UVA-induced generation of reactive oxygen species. J Invest Dermatol 118:582-588.
10. Hand RA, Jia N, Bard M, Craven RJ. 2003. Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. Euk Cell 2:306-317.
11. Jackson AL, Loeb LA. 2001. The contribution of endogenous sources of DNA damage to the multiple mutations in cancer. Mutat Res 477:7-21.
12. Kim DK, Cho ES, Um HD. 2000. Caspase-dependent and -independent events in apoptosis induced by hydrogen peroxide. Exp Cell Res 257:82-88.
13. Kim DK, Cho ES, Lee BR, Um HD. 2001. NF-kappaB mediates the adaptation of human U937 cells to hydrogen peroxide. Free Rad Biol Med 30:563-571.
14. Krebs CJ, Jarvis ED, Chan J, Lydon JP, Ogawa S, Pfaff DW. 2000. A membrane-associated progesterone-binding protein, Dx-25, is regulated by progesterone in brain regions involved in female reproductive behaviors. Proc Natl Acad Sci USA 97:12816-12821.
15. Li Y, Zhang W, Mantell LL, Kazzaz JA, Fein AM, Horowitz S. 1997. Nuclear factor κB is activated by hyperoxia but does not protect from cell death. J Biol Chem 272:20646-20649.
16. Luo Y, Hattori A, Munoz J, Qin Z-H, Roth GS. 1999. Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-κB in rats. Mol Pharm 56:254-264.
17. Martin D, Salinas M, Fujita N, Tsuruo T, Cuadrado A. 2002. Ceramide and reactive oxygen species generated by H202 induce caspase-3-independent degradation of Akt/protein kinase B. J Biol Chem 277:42943-42952.
18. Martindale JL, Holbrook NJ. 2002. Cellular response to oxidative stress: Signaling for suicide and survival. J Cell Physiol 192:1-15.
19. Mates JM, Sanchez-Jimenez FM. 2000. Role of reactive oxygen species in apoptosis: Implications for cancer therapy. Int J Biochem Cell Biol 32:157-170.
20. Mattson MP, Culmsee C, Yu Z, Camandola S. 2000. Roles of nuclear factor kappaB in neuronal survival and plasticity. J Neurochem 74:443-456.
21. Meyer C, Schmid R, Scriba PC, Wehling M. 1996. Purification and partial sequencing of high-affinity progesterone binding sites from porcine liver membranes. Eur J Biochem 239:726-731.
22. 5-like ligand-binding domain. Genome Biol 3:1-5.
23. Richmond A. 2002. NF-κB, chemokine gene transcription and tumor growth. Nat Rev 2:664-674.
24. Rossette C, Karin M. 1996. Ultraviolet light and osmotic stress: activation of the JNK cascade thorugh multiple growth factors and cytokine receptors. Science 274:1194-1197.
25. Selmin O, Lucier GW, Clark GC, Tritscher AM, Vanden Heuvel JP, Gastel JA, Walker NJ, Sutter TR, Bell DA. 1996. Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver. Carcinogenesis 17:2609-2615.
26. Serracino-Inglott F, Habib NA, Mathie RT. 2001. Hepatic ischemia-repurfusion injury. Am J Surg 181:160-166.
27. 2 checkpoint function in human fibroblasts. J Biol Chem 276:21951-21959.
28. Shou Y, Gunasekar PG, Borowitz JL, Isom GE. 2000. Cyanide-induced apoptosis involves oxidative-stress-activated NF-kappaB in cortical neurons. Toxicol Appl Pharmacol 164:196-205.
29. Sutter-Dub M-T. 2002. Rapid non-genomic and genomic responses to progestogens, estrogens, and glucocorticoids in the endocrine pancreatic B cell, the adipocyte, and other cell types. Steroids 67:77-93.
30. Thompson AM, Steel CM, Chetty U, Hawkins RA, Miller WR, Carter DC, Forrest AP, Evans HJ. 1990. p53 gene mRNA expression and chromosome 17p allele loss in breast cancer. Br J Cancer 61:74-78.
31. Vollgraf U, Wegner M, Richter-Landsberg C. 1999. Activation of AP-1 and nuclear factor-kappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes. J Neurochem 73:2501-2509.
32. Wang C-Y, Mayo MW, Baldwin AS, Jr. 1996. TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB. Science 274:784-787.
33. Wang X, McCullough KD, Franke TF, Holbrook NJ. 2000. Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J Biol Chem 275:14624-14531.
34. Wang XT, McCullough KD, Wang XJ, Carpenter G, Holbrook NJ. 2001. Oxidative stress-induced phospholipase C-gamma 1 activation enhances cell survival. J Biol Chem 276:28364-28371.
35. Wen LP, Fahrni JA, Troie S, Guan JL, Orth K, Rosen GD. 1997. Cleavage of focal adhesion kinase by caspases during apoptosis. J Biol Chem 272:26056-26061.
36. Xu LH, Yang X, Craven RJ, Cance WG. 1998. The COOH-terminal domain of the focal adhesion kinase induces loss of adhesion and cell death in human tumor cells. Cell Growth Differ 9:999-1005.
37. Xu LH, Yang X, Bradham C, Brenner DA, Baldwin AS, Craven RJ, Cance WG. 2000. The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. J Biol Chem 275:30597-30604.
38. Yu Z, Zhou D, Cheng G, Mattson MP. 2000. Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease. J Mol Neurosci 15:31-44.
39. Zajchowski D, Band V, Pauzie N, Tager A, Stampfer M, Sager R. 1988. Expression of growth factors and oncogenes in normal and tumor-derived human mammary epithelial cells. Cancer Res 48:7041-7047.
40. Zhuang L, Lin J, Lu ML, Solomon KR, Freeman MR. 2002. Cholesterol-rich lipid rafts mediate Akt-regulated survival in prostate cancer cells. Cancer Res 62:2227-2231.