GPCR assay automation for leveraging lead optimization

Journal of Laboratory Automation

Volumn 17, Issue 4, 2012, Pages 266-274

  Cvijic, Mary Ellen ^a   Chen, Jing ^a   Kubala, Steve ^a   Nolfo, Joseph ^a   Kolodin, Garrett ^a   Zhang, Litao ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

High throughput screening (HTS); Robotics and instrumentation; Screening data analysis

Indexed keywords

DATA TRANSFER; DRUG PRODUCTS; INFORMATION MANAGEMENT; ROBOTICS;

AUTOMATION TECHNOLOGY; COMPOUND COLLECTIONS; DATA REPRODUCIBILITY; DRUG DISCOVERY PROCESS; G PROTEIN COUPLED RECEPTORS; HIGH-THROUGHPUT SCREENING; SCREENING DATA; THERAPEUTIC POTENTIALS;

LEAD COMPOUNDS;

CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR5; G PROTEIN COUPLED RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA;

ARTICLE; AUTOMATED CAROUSEL; BARCODE READER; BINDING ASSAY; CAMERA; CENTRIFUGE; COMPETITIVE LIGAND BINDING ASSAY; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DATA PROCESSING; DATA TRANSMISSION; DRUG DEVELOPMENT; DRUG RESEARCH; DRUG TARGETING; EQUIPMENT DESIGN; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMAGING SYSTEM; INCUBATOR; INFORMATION PROCESSING; INFORMATION TECHNOLOGY; LABORATORY AUTOMATION; LABORATORY DEVICE; LEAD OPTIMIZATION; PROTEIN DETERMINATION; REPRODUCIBILITY; ROBOTICS; SCINTILLATION PROXIMITY ASSAY; SEALER; CHEMISTRY; DRUG ANTAGONISM; DRUG POTENTIATION; DRUG SCREENING; INSTRUMENTATION; METHODOLOGY;

AUTOMATION, LABORATORY; CHEMISTRY, PHARMACEUTICAL; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84868228367     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1177/2211068212442502     Document Type: Article

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