Alterations in the cerebral white matter of genetic high risk offspring of patients with schizophrenia spectrum disorder

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 40, Issue 1, 2013, Pages 187-192

  Francis, Alan N ^a   Bhojraj, Tejas S ^a   Prasad, Konasale M ^b   Montrose, Debra ^b   Eack, Shaun M ^b   Rajarethinam, Rajaprabhakaran ^c   van Elst, Ludger T ^d   Keshavan, Matcheri S ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

FreeSurfer; Genetic high risk; MRI; Offspring; Schizophrenia

Indexed keywords

ADOLESCENT; AGE; ARTICLE; CINGULATE GYRUS; COMPUTER PROGRAM; CONTROLLED STUDY; EDUCATIONAL STATUS; FEMALE; GENETIC PREDISPOSITION; GENETIC RISK; HEMISPHERE; HIGH RISK POPULATION; HUMAN; IMAGE PROCESSING; INTRACRANIAL VOLUME; MALE; NERVOUS SYSTEM PARAMETERS; NEUROIMAGING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PARIETAL LOBE; PROGENY; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SEX DIFFERENCE; UNIVERSITY HOSPITAL; WHITE MATTER;

ADOLESCENT; ADULT; BRAIN; CHILD OF IMPAIRED PARENTS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE FIBERS, MYELINATED; RISK; SCHIZOPHRENIA;

EID: 84868225204     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2012.08.003     Document Type: Article

References (50)

1. Agnew-Blais J, Seidman LJ. Neurocognition in youth and young adults under age 30 at familial risk for schizophrenia: A quantitative and qualitative review. Cogn Neuropsychiatry, in press.
2. Ardekani B.A., Bappal A., D'Angelo D., Ashtari M., Lencz T., Szeszko P.R., et al. Brain morphometry using diffusion-weighted magnetic resonance imaging: application to schizophrenia. Neuroreport 2005, 16(13):1455-1459.
3. Bloemen O.J., de Koning M.B., Schmitz N., Nieman D.H., Becker H.E., de Haan L., et al. White-matter markers for psychosis in a prospective ultra-high-risk cohort. Psychol Med 2010, 40(8):1297-1304. (Aug).
4. Boos H.B., Aleman A., Cahn W., Hulshoff Pol H., Kahn R.S. Brain volumes in relatives of patients with schizophrenia: a meta-analysis. Arch Gen Psychiatry 2007, 64(3):297-304. (Mar).
5. Breier A., Buchanan R.W., Elkashef A., Munson R.C., Kirkpatrick B., Gellad F. Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures. Arch Gen Psychiatry 1992, 49(12):921-926. (Dec).
6. Buchanan R.W., Francis A., Arango C., Miller K., Lefkowitz D.M., McMahon R.P., et al. Morphometric assessment of the heteromodal association cortex in schizophrenia. Am J Psychiatry 2004, 161(2):322-331. (Feb).
7. Buchsbaum M.S., Schoenknecht P., Torosjan Y., Newmark R., Chu K.W., Mitelman S., et al. Diffusion tensor imaging of frontal lobe white matter tracts in schizophrenia. Arch Gen Psychiatry 2006, 5:19. (Nov 28).
8. Crow T.J. Schizophrenia as a transcallosal misconnection syndrome. Schizophr Res 1998, 30(2):111-114.
9. Dale A.M., Fischl B., Sereno M.I. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 1999, 9(2):179-194.
10. da Silva Alves F., Schmitz N., Bloemen O., van der Meer J., Meijer J., Boot E., et al. White matter abnormalities in adults with 22q11 deletion syndrome with and without schizophrenia. Schizophr Res 2011, 132(1):75-83. (Oct).
11. Dale A.M., Fischl B., Sereno M.I. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 1999, 9(2):179-194. (Feb).
12. Davatzikos C. Voxel-based morphometric analysis using shape transformations. Int Rev Neurobiol 2005, 66:125-146.
13. Desikan R.S., Segonne F., Fischl B., Quinn B.T., Dickerson B.C., Blacker D., et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 2006, 31(3):968-980.
14. Di X., Chan R.C., Gong Q.Y. White matter reduction in patients with schizophrenia as revealed by voxel-based morphometry: an activation likelihood estimation meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry 2009, 33(8):1390-1394. (Nov 13).
15. First M., Spitzer R., Williams J., Gibbon M. Structured clinical interview for DSM-IV (SCID) 1995, American Psychiatric Association, Washington, DC.
16. Fischl B., Wald L.L. Phase maps reveal cortical architecture. Proc Natl Acad Sci U S A 2007, 104(28):11513-11514.
17. Fischl B., Sereno M.I., Tootell R.B., Dale A.M. High-resolution intersubject averaging and a coordinate system for the cortical surface. Hum Brain Mapp 1999, 8(4):272-284.
18. Fischl B., Liu A., Dale A.M. Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex. IEEE Trans Med Imaging 2001, 20(1):70-80. (Jan).
19. Fischl B., Salat D.H., Busa E., Albert M., Dieterich M., Haselgrove C., et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 2002, 33(3):341-355.
20. Fischl B., van der Kouwe A., Destrieux C., Halgren E., Segonne F., Salat D.H., et al. Automatically parcellating the human cerebral cortex. Cereb Cortex 2004, 14(1):11-22.
21. Fischl B., Salat D.H., van der Kouwe A.J., Makris N., Ségonne F., Quinn B.T., et al. Sequence-independent segmentation of magnetic resonance images. Neuroimage 2004, 23(Suppl. 1):S69-S84.
22. Francis A.N., Bhojraj T.S., Kulkarni S., Prasad K.M., Eack S.M., Montrose D.M., et al. Abnormalities of the Corpus Callosum in Non-Psychotic high-risk offspring of Schizophrenia patients. Psychiatry Res Neuroimaging 2011, 191(1):9-15. (30 January).
23. Friston K.J., Frith C.D. Schizophrenia: a disconnection syndrome?. Clin Neurosci 1995, 3(2):89-97. (Review).
24. Gilbert A.R., Rosenberg D.R., Harenski K., Spencer S., Sweeney J.A., Keshavan M.S. Thalamic volumes in patients with first-episode schizophrenia. Am J Psychiatry 2001, 158(4):618-624.
25. Giuliani N.R., Calhoun V.D., Pearlson G.D., Francis A., Buchanan R.W. Voxel-based morphometry versus region of interest: a comparison of two methods for analyzing gray matter differences in schizophrenia. Schizophr Res 2005, 74(2-3):135-147.
26. Hubl D., Koenig T., Strik W., Federspiel A., Kreis R., Boesch C., et al. Pathways that make voices: white matter changes in auditory hallucinations. Arch Gen Psychiatry 2004, 61(7):658-668. (Jul).
27. Hulshoff Pol H.E., Schnack H.G., Bertens M.G., van Haren N.E., van der Tweel I., Staal W.G., et al. Volume changes in gray matter in patients with schizophrenia. Am J Psychiatry 2002, 159(2):244-250. (Feb).
28. Karlsgodt K.H., Sun D., Jimenez A.M., Lutkenhoff E.S., Willhite R., van Erp T.G., et al. Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia. Dev Psychopathol 2008, 20(4):1297-1327. (Fall. Review).
29. Keshavan M.S., Tandon R., Boutros N.N., Nasrallah H.A. Schizophrenia, "just the facts": what we know in 2008a Part 3: neurobiology. Schizophr Res 2008, 106(2-3):89-107.
30. Keshavan M., Montrose D.M., Rajarethinam R., Diwadkar V., Prasad K., Sweeney J.A. Psychopathology among offspring of parents with schizophrenia: relationship to premorbid impairments. Schizophr Res 2008, 103(1-3):114-120. (Aug).
31. Kubicki M., McCarley R.W., Shenton M.E. Evidence for white matter abnormalities in schizophrenia. Curr Opin Psychiatry 2005, 18(2):121-134. (Mar).
32. Kubicki M., McCarley R., Westin C.F., Park H.J., Maier S., Kikinis R., et al. A review of diffusion tensor imaging studies in schizophrenia. J Psychiatr Res 2007, 41(1-2):15-30. (Jan-Feb).
33. Lawrie S.M., Whalley H.C., Abukmeil S.S., Kestelman J.N., Donnelly L., Miller P., et al. Brain structure, genetic liability, and psychotic symptoms in subjects at high risk of developing schizophrenia. Biol Psychiatry 2001, 49(10):811-823.
34. Lawrie S.M., McIntosh A.M., Hall J., Owens D.G., Johnstone E.C. Brain structure and function changes during the development of schizophrenia: the evidence from studies of subjects at increased genetic risk. Schizophr Bull 2008, 34(2):330-340. (Mar).
35. Lymer G.K., Job D.E., William T., Moorhead J., McIntosh A.M., Owens D.G., et al. Brain-behaviour relationships in people at high genetic risk of schizophrenia. Neuroimage 2006, 33(1):275-285.
36. MacDonald A.W., Schulz S.C. What we know: findings that every theory of schizophrenia should explain. Schizophr Bull 2009, 35(3):493-508.
37. Mathalon D.H., Rapoport J.L., Davis K.L., Krystal J.H. Neurotoxicity, neuroplasticity, and magnetic resonance imaging morphometry. Arch Gen Psychiatry 2003, 60(8):846-848. (Aug).
38. McGrath J., Saha S., Chant D., Welham J. Schizophrenia: a concise overview of incidence, prevalence, and mortality. Epidemiol Rev 2008, 30:67-76.
39. Meda S.A., Giuliani N.R., Calhoun V.D., Jagannathan K., Schretlen D.J., Pulver A., et al. A large scale (N=400) investigation of gray matter differences in schizophrenia using optimized voxel-based morphometry. Schizophr Res 2008, 101(1-3):95-105.
40. Olabi B., Ellison-Wright I., McIntosh A.M., Wood S.J., Bullmore E., Lawrie S.M. Are there progressive brain changes in schizophrenia? A meta-analysis of structural magnetic resonance imaging studies. Biol Psychiatry 2011, 70(1):88-96. (Jul 1).
41. Salat D.H., Greve D.N., Pacheco J.L., Quinn B.T., Helmer K.G., Buckner R.L., et al. Regional white matter volume differences in nondemented aging and Alzheimer's disease. Neuroimage 2009, 44(4):1247-1258. (Feb 15).
42. Sanfilipo M., Lafargue T., Rusinek H., Arena L., Loneragan C., Lautin A., et al. Volumetric measure of the frontal and temporal lobe regions in schizophrenia: relationship to negative symptoms. Arch Gen Psychiatry 2000, 57(5):471-480. (May).
43. Ségonne F., Dale A.M., Busa E., Glessner M., Salat D., Hahn H.K., et al. A hybrid approach to the skull stripping problem in MRI. Neuroimage 2004, 22(3):1060-1075. (Jul).
44. Ségonne F., Pacheco J., Fischl B. Geometrically accurate topology-correction of cortical surfaces using nonseparating loops. IEEE Trans Med Imaging 2007, 26(4):518-529. (Apr).
45. Shenton M.E., Dickey C.C., Frumin M., McCarley R.W. A review of MRI findings in schizophrenia. Schizophr Res 2001, 49(1-2):1-52.
46. Silbersweig D., Stern E. Functional neuroimaging of hallucinations in schizophrenia: toward an integration of bottom-up and top-down approaches. Mol Psychiatry 1996, 1(5):367-375. (Nov).
47. Silbersweig D., Stern E. Towards a functional neuroanatomy of conscious perception and its modulation by volition: implications of human auditory neuroimaging studies. Philos Trans R Soc Lond B Biol Sci 1998, 353(1377):1883-1888. (Nov 29).
48. Szeszko P.R., Ardekani B.A., Ashtari M., Kumra S., Robinson D.G., Sevy S., et al. White matter abnormalities in first-episode schizophrenia or schizoaffective disorder: a diffusion tensor imaging study. Am J Psychiatry 2005, 162(3):602-605. (Mar).
49. van der Kouwe A.J., Benner T., Salat D.H., Fischl B. Brain morphometry with multiecho MPRAGE. Neuroimage 2008, 40(2):559-569.
50. Wible C.G., Anderson J., Shenton M.E., Kricun A., Hirayasu Y., Tanaka S., et al. Prefrontal cortex, negative symptoms, and schizophrenia: an MRI study. Psychiatry Res 2001, 108(2):65-78. (Nov 30).