Admission base excess as a predictor of transfusion requirement and mortality in dogs with blunt trauma: 52 cases (2007-2009)

Journal of Veterinary Emergency and Critical Care

Volumn 22, Issue 5, 2012, Pages 588-594

  Stillion, Jenefer R ^a   Fletcher, Daniel J ^a  

^a Cornell University ^*  (United States)

Author keywords

Hemorrhage; Injury; Occult hypoperfusion; Prognostic indicator

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; BLOOD TRANSFUSION; DISORDERS OF ACID BASE BALANCE; DOG; DOG DISEASE; INJURY; MORTALITY; RETROSPECTIVE STUDY; STATISTICS; TRAFFIC ACCIDENT;

ACCIDENTS, TRAFFIC; ACID-BASE IMBALANCE; ANIMALS; BLOOD TRANSFUSION; DOG DISEASES; DOGS; RETROSPECTIVE STUDIES; WOUNDS AND INJURIES;

ANIMALIA; CANIS FAMILIARIS;

EID: 84868216128     PISSN: 14793261     EISSN: 14764431     Source Type: Journal    
DOI: 10.1111/j.1476-4431.2012.00798.x     Document Type: Article

References (49)

1. Simpson SA, Syring R, Otto CM. Severe blunt trauma in dogs: 235 cases (1997-2003). J Vet Emerg Crit Care 2009; 19(6):588-602.
2. Muir W. Trauma: physiology, pathophysiology, and clinical implications. J Vet Emerg Crit Care 2006; 16(4):253-263.
3. Boldt J, Ince C. The impact of fluid therapy on microcirculation and tissue oxygenation in hypovolemic patients: a review. Intensive Care Med 2010; 36(8):1299-1308.
4. Kincaid EH, Miller PR, Meredith JW, et al. Elevated arterial base deficit in trauma patients: a marker of impaired oxygen utilization. J Am Coll Surg 1998; 187(4):384-392.
5. Paladino L, Sinert R, Wallace D, et al. The utility of base deficit and arterial lactate in differentiating major from minor injury in trauma patients with normal vital signs. Resuscitation 2008; 77(3):363-368.
6. Meregalli A, Oliveira RP, Friedman G. Occult hypoperfusion is associated with increased mortality in hemodynamically stable, high-risk, surgical patients. Crit Care 2004; 8(2):R60-R65.
7. Callaway DW, Shapiro NI, Donnino MW, et al. Serum lactate and base deficit as predictors of mortality in normotensive elderly blunt trauma patients. J Trauma 2009; 66(4):1040-1044.
8. Blow O, Magliore L, Claridge JA, et al. The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma. J Trauma 1999; 47(5):964-969.
9. Zehtabchi S, Baron BJ. Utility of base deficit for identifying major injury in elder trauma patients. Acad Emerg Med 2007; 14(9):829-831.
10. Andel D, Kamolz L-P, Roka J, et al. Base deficit and lactate: early predictors of morbidity and mortality in patients with burns. J Int Soc Burn Injuries 2007;33(8):973-978.
11. Davis JW, Shackford SR, Holbrook TL. Base deficit as a sensitive indicator of compensated shock and tissue oxygen utilization. Surg Gynecol Obstet 1991; 173(6):473-476.
12. Davis JW, Mackersie RC, Holbrook TL, et al. Base deficit as an indicator of significant abdominal injury. Ann Emerg Med 1991; 20(8):842-844.
13. Randolph LC, Takacs M, Davis KA. Resuscitation in the pediatric trauma population: admission base deficit remains an important prognostic indicator. J Trauma 2002; 53(5):838-842.
14. Wilson M. Diagnosis and monitoring of hemorrhagic shock during the initial resuscitation of multiple trauma patients: a review. J Emerg Med 2003; 24(4):413-422.
15. Davis JW, Parks SN, Kaups KL, et al. Admission base deficit predicts transfusion requirements and risk of complications. J Trauma 1996; 41(5):769-774.
16. Jung J, Eo E, Ahn K, et al. Initial base deficit as predictors for mortality and transfusion requirement in the severe pediatric trauma except brain injury. Trauma 2009; 25(9):579-581.
17. Sauaia A, Moore FA, Moore EE, Moser KS, Brennan R, Read RA, Pons PT. Epidemiology of trauma deaths: a reassessment. 1995 Feb;38(2):185-193.
18. Boysen SR, Rozanski EA, Tidwell AS, et al. Evaluation of a focused assessment with sonography for trauma protocol to detect free abdominal fluid in dogs involved in motor vehicle accidents. J Am Vet Med Assoc 2004; 225(8):1198-1204.
19. Ilkiw JE, Rose RJ, Martin ICA. A comparison of simultaneously collected arterial, mixed venous, jugular venous and cephalic venous blood samples in the assessment of blood-gas and acid-base status in the dog. J Vet Int Med 1991; 5(5):294-298.
20. Davis JW. The relationship of base deficit to lactate in porcine hemorrhagic shock and resuscitation. J Trauma 1994; 36(2):168-172.
21. Streeter EM, Rozanski EA, Laforcade-Buress AD, et al. Evaluation of vehicular trauma in dogs: 239 cases (January-December 2001). J Am Vet Med Assoc 2009; 235(4):405-408.
22. Rockar Ra, Drobatz KS, Shofer FS. Development of a scoring system for the veterinary trauma patient. J Vet Emerg Crit Care 1994; 4(2):77-83.
23. Kauvar DS, Lefering R, Wade CE. Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations. J Trauma 2006; 60(6 Suppl):S3-S11.
24. Geeraedts LMG, Kaasjager HAH, van Vugt AB, et al. Exsanguination in trauma: a review of diagnostics and treatment options. Injury 2009; 40(1):11-20.
25. Feldman BF, Zinkl JG, Schalm OW. Schalm's veterinary hematology, 5th ed. Ames, IA: Wiley-Blackwell; 2000.
26. Boag AK, Hughes D. Assessment and treatment of perfusion abnormalities in the emergency patient. The Veterinary Clinics of North America. Small Anim Pract 2005; 35(2):319-342.
27. Raum MR, Nijsten MWN, Vogelzang M, et al. Emergency trauma score: an instrument for early estimation of trauma severity. Crit Care Med 2009; 37(6):1972-1977.
28. Malinoski DJ, Todd SR, Slone S, et al. Correlation of central venous and arterial blood gas measurements in mechanically ventilated trauma patients. Arch Surg 2005; 140(11):1122-1125.
29. Kelly AM, McAlpine R, Kyle E. Venous pH can safely replace arterial pH in the initial evaluation of patients in the emergency department. Emerg Med J 2001; 18(5):340-342.
30. Middleton P, Kelly A-M, Brown J, et al. Agreement between arterial and central venous values for pH, bicarbonate, base excess, and lactate. Emerg Med J 2006; 23(8):622-624.
31. Abramson D, Scalea TM, Hitchcock R, et al. Lactate clearance and survival following injury. J Trauma 1993; 35(4):584-588; discussion 588-589.
32. Lagutchik MS, Ogilvie GK, Hackett TB, et al. Increased lactate concentrations in III and injured dogs. J Vet Emerg Crit Care 1998; 8(2):117-127.
33. Mikulaschek A, Henry SM, Donovan R, et al. Serum lactate is not predicted by anion gap or base excess after trauma resuscitation. J Trauma 1996; 40(2):218-222; discussion 222-224.
34. Kaplan LJ, Kellum JA. Comparison of acid-base models for prediction of hospital mortality after trauma. Crit Care 2008; 29(6):662-666.
35. Hobbs TR, O'Malley JP, Khouangsathiene S, et al. Comparison of lactate, base excess, bicarbonate, and pH as predictors of mortality after severe trauma in rhesus macaques (Macaca mulatta). Comp Med 2010; 60(3):233-239.
36. Husain F. Serum lactate and base deficit as predictors of mortality and morbidity. Am J Surg 2003; 185(5):485-491.
37. Luchette FA, Jenkins WA, Friend LA, et al. Hypoxia is not the sole cause of lactate production during shock. J Trauma 2002; 52(3):415-419.
38. Billeter A, Turina M, Seifert B, et al. Early serum procalcitonin, interleukin-6, and 24-hour lactate clearance: useful indicators of septic infections in severely traumatized patients. World J Surg 2009; 33(3):558-566.
39. Durham RM, Moran JJ MJ. Multiple organ failure in trauma patients. [J Trauma. 2003] - PubMed result [Internet]. J Trauma. 2003 [cited 2011 Jul 22];608-16. Available from: http://www.ncbi. nlm.nih.gov/pubmed?term=Duram RM lactate
40. Schulman AM, Claridge JA, Young JS. Young versus old: factors affecting mortality after blunt traumatic injury. Am Surg 2002; 68(11):942-947; discussion 947-948.
41. Tornetta P, Mostafavi H, Riina J, et al. Morbidity and mortality in elderly trauma patients. J Trauma 1999; 46(4):702-706.
42. Floccard B, Rugeri L, Faure A, et al. Early coagulopathy in trauma patients: an on-scene and hospital admission study. Injury 2010; 43(1):26-32.
43. Mofidi M, Hasani A, Kianmehr N. Determining the accuracy of base deficit in diagnosis of intra-abdominal injury in patients with blunt abdominal trauma. Am J Emerg Med 2010; 28(8):933-936.
44. Thom O, Taylor DM, Wolfe RE, et al. Pilot study of the prevalence, outcomes and detection of occult hypoperfusion in trauma patients. Emerg Med J 2010; 27(6):470-472.
45. Lier H, Böttiger BW, Hinkelbein J, Krep H, Bernhard M. Coagulation management in multiple trauma: a systematic review. Intensive Care Med 2011; 37(4):572-582.
46. Shaz BH, Winkler AM, James AB, et al. Pathophysiology of early trauma-induced coagulopathy: emerging evidence for hemodilution and coagulation factor depletion. J Trauma 2011; 70(6):1401-1407.
47. Dente CJ, Shaz BH, Nicholas JM, et al. Improvements in early mortality and coagulopathy are sustained better in patients with blunt trauma after institution of a massive transfusion protocol in a civilian level I trauma center. J Trauma 2009; 66(6):1616-1624.
48. Shaz BH, Dente CJ, Nicholas J, et al. Increased number of coagulation products in relationship to red blood cell products transfused improves mortality in trauma patients. Transfusion 2010; 50(2):493-500.
49. Corwin HL. The CRIT study: anemia and blood transfusion in the critically ill - current clinical practice in the United States. Crit Care Med 2004; 32(1):39-52.