Protective effects of vasoactive intestinal peptide (VIP) in ischemic retinal degeneration

Journal of Molecular Neuroscience

Volumn 48, Issue 3, 2012, Pages 501-507

  Szabadfi, K ^a   Danyadi, B ^a   Kiss, P ^a   Tamas, A ^a   Fabian, E ^a   Gabriel, R ^a   Reglodi, D ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Ischemia; PACAP; Protection; Retina; VIP

Indexed keywords

PROTECTIVE AGENT; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIATERAL COMMON CAROTID ARTERY OCCLUSION; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; HISTOPATHOLOGY; MALE; NERVE CELL; NONHUMAN; RAT; RETINA ISCHEMIA;

ANIMALS; APOPTOSIS; CAROTID ARTERY, COMMON; CAROTID STENOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; INTRAVITREAL INJECTIONS; ISCHEMIA; MALE; MODELS, NEUROLOGICAL; NEUROPROTECTIVE AGENTS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, WISTAR; RETINAL DEGENERATION; RETINAL NEURONS; RETINAL VESSELS; RETINITIS; TIME FACTORS; VASOACTIVE INTESTINAL PEPTIDE;

RATTUS;

EID: 84868206069     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9774-9     Document Type: Article

References (38)

1. Atlasz T, Babai N, Kiss P et al (2007a) Pituitary adenylate cyclase activating polypeptide is protective in bilateral carotid occlusioninduced retinal lesion in rats. Gen Comp Endocrinol 153:108-114 (Pubitemid 47102321)
2. Atlasz T, Babai N, Reglodi D et al (2007b) Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration. Neurotox Res 12:105-111
3. Atlasz T, Szabadfi K, Kiss P et al (2008) PACAP-mediated neuroprotection of neurochemically identified cell types in MSGinduced retinal regeneration. J Mol Neurosci 36:97-104
4. Atlasz T, Szabadfi K, Reglodi D et al (2009) Effects of pituitary adenylate cyclase activating polypeptide (PACAP1-38) and its fragments on retinal degeneration induced by neonatal MSG treatment. Ann N Y Acad Sci 1163:348-352
5. Atlasz T, Szabadfi K, Kiss P et al (2010a) Evaluation of the protective effects of PACAP with cell-specific markers in ischemia-induced retinal degeneration. Brain Res Bull 81:497-504
6. Atlasz T, Szabadfi K, Kiss P et al (2010b) Pituitary adenylate cyclase activating polypeptide in the retina: focus on the retinoprotective effects. Ann N Y Acad Sci 1200:128-139
7. Atlasz T, Szabadfi K, Kiss P et al (2011) Effects of PACAP in UV-A radiation-induced retinal degeneration models in rats. J Mol Neurosci 43:51-57
8. Babai N, Atlasz T, Tamas A et al (2006) Search for the optimal monosodium glutamate treatment schedule to study the neuroprotective effects of PACAP in the retina. Ann N Y Acad Sci 1070:149-155 (Pubitemid 44126633)
9. Belokopytov M, Shulman S, Dubinsky G, Gozes I, Belkin M, Rosner M (2011) Ameliorative effect of NAP on laser-induced retinal damage. Acta Ophthalmol 89:e126-e131
10. Dejda A, Sokolowska P, Nowak JZ (2005) Neuroprotective potential of three neuropeptides PACAP, VIP and PHI. Pharmacol Rep 57:307-320 (Pubitemid 41030690)
11. Endo K, Nakamachi T, Seki T et al (2011) Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse. J Mol Neurosci 43:22-29
12. Farkas E, Luiten PG, Bari F (2007) Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases. Brain Res Rev 54:162-180 (Pubitemid 46498166)
13. Ganea D, Delgado M (2002) Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) as modulators of both innate and adaptive immunity. Crit Rev Oral Biol Med 13:229-237 (Pubitemid 34791208)
14. Gozes I, Brenneman DE (2000) A new concept in neuroprotection. J Mol Neurosci 14:61-68
15. Gozes I, Divinsky I, Pilzer I, Fridkin M, Brenneman DE, Spier AD (2003) From vasoactive intestinal peptide (VIP) through activitydependent neuroprotective protein (ADNP) to NAP. J Mol Neurosci 20:315-322 (Pubitemid 38146988)
16. Jehle T, Dimitriu C, Auer S et al (2008) The neuropeptide NAP provides neuroprotection against retinal ganglion cell damage after retinal ischemia and optic nerve crush. Graefes Arch Clin Exp Ophthalmol 246:1255-1263
17. Laburthe M, Couvineau A, Tan V (2007) Class II G protein-coupled receptors for VIP and PACAP: structure, models of activation and pharmacology. Peptides 28:1631-1639 (Pubitemid 47371033)
18. Lagreze WA, Pielen A, Steingart R et al (2005) The peptides ADNF-9 and NAP increase survival and neurite outgrowth of rat retinal ganglion cells in vitro. Invest Opthalmol Vis Sci 46:933-938 (Pubitemid 41321030)
19. Masmoudi-Kouki O, Gandolfo P, Castel H et al (2007) Role of PACAP and VIP in astroglial functions. Peptides 28:1753-1760 (Pubitemid 47361428)
20. Mester L, Szabo A, Atlasz T et al (2009) Protection against chronic hypoperfusion-induced retinal neurodegeneration by PARP inhibition via activation of PI3-kinase Akt pathway and suppression of JNK and p38 MAP kinases. Neurotox Res 18:68-76
21. Pilzer I, Gozes I (2006) VIP provides cellular protection through a specific splice variant of the PACAP receptor: a new neuroprotection target. Peptides 27:2867-2876 (Pubitemid 44584412)
22. Rangon CM, Goursaud S, Medja F et al (2005) VPAC2 receptors mediate vasoactive intestinal peptide induced neuroprotection against neonatal excitotoxic brain lesions in mice. J Pharm Exp Therap 314:745-752 (Pubitemid 41043858)
23. Seki T, Nakatani M, Taki C et al (2006) Neuroprotective effect of PACAP against kainic acid (KA)-induced neurotoxicity in rat retina. Ann N Y Acad Sci 1070:531-534 (Pubitemid 44126698)
24. Seki T, Itoh H, Nakamachi T, Shioda S (2008) Suppression of ganglion cell death by PACAP following optic nerve transection in the rat. J Mol Neurosci 36:57-60
25. Seki T, Itoh H, Nakamachi T et al (2011) Suppression of rat retinal ganglion cell death by PACAP following transient ischemia induced by high intraocular pressure. J Mol Neurosci 43:30-34
26. Shoge K, Mishima HK, Saitoh T et al (1998) Protective effects of vasoactive intestinal peptide against delayed glutamate neurotoxicity in cultured retina. Brain Res 809:127-136 (Pubitemid 29003433)
27. Shoge K, Mishima HK, Saitoh T et al (1999) Attenuation by PACAP of glutamate-induced neurotoxicity in cultured retinal neurons. Brain Res 839:66-73 (Pubitemid 29389794)
28. Somogyvari-Vigh A, Reglodi D (2004) Pituitary adenylate cyclase activating polypeptide: a potential neuroprotective peptide. Curr Pharm Des 10(23):2861-2889 (Pubitemid 39172068)
29. Szabadfi K, Atlasz T, Reglodi D et al (2009) Urocortin 2 protects against retinal degeneration following bilateral common carotid artery occlusion in the rat. Neurosci Lett 455:42-45
30. Szabadfi K, Mester L, Reglodi D et al (2010) Novel neuroprotective strategies in ischemic retinal lesions. Int J Mol Sci 11:544-561
31. Szabadfi K, Atlasz T, Kiss P et al (2012a) Protective effects of the neuropeptide PACAP in diabetic retinopathy. Cell Tissue Res 348:37-46
32. Szabadfi K, Atlasz T, Kiss P et al (2012b) Mice deficient in pituitary adenylate cyclase activating polypeptide (PACAP) are more susceptible to retinal ischemic injury in vivo. Neurotox Res 21:41-48
33. Tamas A, Gabriel R, Racz B et al (2004) Effects of pituitary adenylate cyclase activating polypeptide in retinal degeneration induced by monosodium-glutamate. Neurosci Lett 372:110-113 (Pubitemid 39505238)
34. Troger J, Neyer S, Heufler C et al (2001) Substance P and vasoactive intestinal polypeptide in the streptozotocin-induced diabetic rat retina. Invest Ophthalmol Vis Sci 42:1045-1050 (Pubitemid 32289802)
35. Tuncel N, Basmak H, Uzuner K et al (1996) Protection of rat retina from ischemia-reperfusion injury by vasoactive intestinal peptide (VIP): the effects of VIP on lipid peroxidation and antioxidant enzyme activity of retina and choroid. Ann N Y Acad Sci 805:489-498 (Pubitemid 27058046)
36. Vaudry D, Falluel-Morel A, Bourgault S et al (2009) Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery. Pharmacol Rev 61(3):283-357
37. Yang J, Song TB, Zhao ZH, Qiu SD, Hu XD, Chang L (2011) Vasoactive intestinal peptide protects against ischemic brain damage induced by focal cerebral ischemia in rats. Brain Res 1398:94-101
38. Zheng Y, Zeng H, She H, Liu H, Sun N (2010) Expression of peptide NAP in rat retinal Muller cells prevents hypoxia-induced retinal injuries and promotes retinal neurons growth. Biomed Pharmacother 64:417-423