-
1
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
S. Hirota, K. Isozaki, and Y. Moriyama Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors Science 279 1998 577 580
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
-
2
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
M.C. Heinrich, C.L. Corless, and A. Duensing PDGFRA activating mutations in gastrointestinal stromal tumors Science 299 2003 708 710
-
(2003)
Science
, vol.299
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
-
3
-
-
77949898532
-
Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: A meta-analysis of 1,640 patients
-
A.G. GSTM Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: a meta-analysis of 1,640 patients J Clin Oncol 28 2010 1247 1253
-
(2010)
J Clin Oncol
, vol.28
, pp. 1247-1253
-
-
Gstm, A.G.1
-
4
-
-
50249092801
-
Heterogeneity of kinase inhibitor resistance mechanisms in GIST
-
B. Liegl, I. Kepten, and C. Le Heterogeneity of kinase inhibitor resistance mechanisms in GIST J Pathol 216 2008 64 74
-
(2008)
J Pathol
, vol.216
, pp. 64-74
-
-
Liegl, B.1
Kepten, I.2
Le, C.3
-
5
-
-
34250013899
-
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas
-
E. Hernando, E. Charytonowicz, and M.E. Dudas The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas Nat Med 13 2007 748 753
-
(2007)
Nat Med
, vol.13
, pp. 748-753
-
-
Hernando, E.1
Charytonowicz, E.2
Dudas, M.E.3
-
6
-
-
49649119001
-
Molecular characterization of pediatric gastrointestinal stromal tumors
-
N.P. Agaram, M.P. Laquaglia, and B. Ustun Molecular characterization of pediatric gastrointestinal stromal tumors Clin Cancer Res 14 2008 3204 3215
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3204-3215
-
-
Agaram, N.P.1
Laquaglia, M.P.2
Ustun, B.3
-
7
-
-
46149111291
-
Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients
-
C. Braconi, R. Bracci, and I. Bearzi Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients Ann Oncol 19 2008 1293 1298
-
(2008)
Ann Oncol
, vol.19
, pp. 1293-1298
-
-
Braconi, C.1
Bracci, R.2
Bearzi, I.3
-
8
-
-
46149104384
-
Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors
-
C. Tarn, L. Rink, and E. Merkel Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors Proc Natl Acad Sci U S A 105 2008 8387 8392
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 8387-8392
-
-
Tarn, C.1
Rink, L.2
Merkel, E.3
-
9
-
-
72449212435
-
Insulin-like growth factor 1 receptor expression in wild-type GISTs: A potential novel therapeutic target
-
M.A. Pantaleo, A. Astolfi, and M. Di Battista Insulin-like growth factor 1 receptor expression in wild-type GISTs: a potential novel therapeutic target Int J Cancer 125 2009 2991 2994
-
(2009)
Int J Cancer
, vol.125
, pp. 2991-2994
-
-
Pantaleo, M.A.1
Astolfi, A.2
Di Battista, M.3
-
10
-
-
67650688576
-
Expression of insulin-like growth factor 2 in mesenchymal neoplasms
-
S.E. Steigen, D.F. Schaeffer, R.B. West, and T.O. Nielsen Expression of insulin-like growth factor 2 in mesenchymal neoplasms Mod Pathol 22 2009 914 921
-
(2009)
Mod Pathol
, vol.22
, pp. 914-921
-
-
Steigen, S.E.1
Schaeffer, D.F.2
West, R.B.3
Nielsen, T.O.4
-
11
-
-
78049495856
-
Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification
-
K.A. Janeway, M.J. Zhu, J. Barretina, A. Perez-Atayde, G.D. Demetri, and J.A. Fletcher Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification Int J Cancer 127 2010 2718 2722
-
(2010)
Int J Cancer
, vol.127
, pp. 2718-2722
-
-
Janeway, K.A.1
Zhu, M.J.2
Barretina, J.3
Perez-Atayde, A.4
Demetri, G.D.5
Fletcher, J.A.6
-
12
-
-
56749184290
-
Insulin and insulin-like growth factor signalling in neoplasia
-
M. Pollak Insulin and insulin-like growth factor signalling in neoplasia Nat Rev Cancer 8 2008 915 928
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 915-928
-
-
Pollak, M.1
-
13
-
-
27244442412
-
Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: A report of two cases
-
D. Pink, D. Schoeler, and T. Lindner Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: a report of two cases J Clin Oncol 23 2005 6809 6811
-
(2005)
J Clin Oncol
, vol.23
, pp. 6809-6811
-
-
Pink, D.1
Schoeler, D.2
Lindner, T.3
-
14
-
-
27544483546
-
Non-islet cell tumour hypoglycaemia in a patient with a gastrointestinal stromal tumour
-
B. Rikhof, G. Van Den Berg, and W.T. Van Der Graaf Non-islet cell tumour hypoglycaemia in a patient with a gastrointestinal stromal tumour Acta Oncol 44 2005 764 766
-
(2005)
Acta Oncol
, vol.44
, pp. 764-766
-
-
Rikhof, B.1
Van Den Berg, G.2
Van Der Graaf, W.T.3
-
15
-
-
33748092018
-
Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia
-
I. Fukuda, N. Hizuka, and Y. Ishikawa Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia Growth Horm IGF Res 16 2006 211 216
-
(2006)
Growth Horm IGF Res
, vol.16
, pp. 211-216
-
-
Fukuda, I.1
Hizuka, N.2
Ishikawa, Y.3
-
16
-
-
33846939042
-
Hypoglycemia in the setting of advanced gastrointestinal stromal tumor
-
J. Guiteau, M. Fanucchi, and A. Folpe Hypoglycemia in the setting of advanced gastrointestinal stromal tumor Am Surg 72 2006 1225 1230
-
(2006)
Am Surg
, vol.72
, pp. 1225-1230
-
-
Guiteau, J.1
Fanucchi, M.2
Folpe, A.3
-
17
-
-
33745525270
-
Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinib
-
P. Hamberg, F.A. de Jong, J.G. Boonstra, J. van Doorn, J. Verweij, and S. Sleijfer Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinib J Clin Oncol 24 2006 e30 e31
-
(2006)
J Clin Oncol
, vol.24
-
-
Hamberg, P.1
De Jong, F.A.2
Boonstra, J.G.3
Van Doorn, J.4
Verweij, J.5
Sleijfer, S.6
-
18
-
-
33846817099
-
Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: A case report
-
G.A. Escobar, W.A. Robinson, and T.L. Nydam Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report BMC Cancer 7 2007 13
-
(2007)
BMC Cancer
, vol.7
, pp. 13
-
-
Escobar, G.A.1
Robinson, W.A.2
Nydam, T.L.3
-
19
-
-
0028956715
-
Insulin-like growth factor binding proteins and tumor hypoglycemia
-
J. Zapf Insulin-like growth factor binding proteins and tumor hypoglycemia Trends Endocrinol Metab 6 1995 37 42
-
(1995)
Trends Endocrinol Metab
, vol.6
, pp. 37-42
-
-
Zapf, J.1
-
20
-
-
0347994028
-
Doege-Potter syndrome: Hypoglycemia associated with malignant solitary fibrous tumor
-
H. Zafar, C.H. Takimoto, and G. Weiss Doege-Potter syndrome: hypoglycemia associated with malignant solitary fibrous tumor Med Oncol 20 2003 403 408
-
(2003)
Med Oncol
, vol.20
, pp. 403-408
-
-
Zafar, H.1
Takimoto, C.H.2
Weiss, G.3
-
21
-
-
40749128979
-
IGF2: Epigenetic regulation and role in development and disease
-
W. Chao, and P.A. D'Amore IGF2: epigenetic regulation and role in development and disease Cytokine Growth Factor Rev 19 2008 111 120
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 111-120
-
-
Chao, W.1
D'Amore, P.A.2
-
22
-
-
77953528175
-
IGF2 over-expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting
-
M. Hajdu, S. Singer, R.G. Maki, G.K. Schwartz, M.L. Keohan, and C.R. Antonescu IGF2 over-expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting J Pathol 221 2010 300 307
-
(2010)
J Pathol
, vol.221
, pp. 300-307
-
-
Hajdu, M.1
Singer, S.2
Maki, R.G.3
Schwartz, G.K.4
Keohan, M.L.5
Antonescu, C.R.6
-
23
-
-
85026339189
-
Loss of imprinting of IGF2 and the epigenetic progenitor model of cancer
-
M.B. Leick, C.M. Shoff, E.C. Wang, J.L. Congress, and G.I. Gallicano Loss of imprinting of IGF2 and the epigenetic progenitor model of cancer Am J Stem Cell 1 2012 59 74
-
(2012)
Am J Stem Cell
, vol.1
, pp. 59-74
-
-
Leick, M.B.1
Shoff, C.M.2
Wang, E.C.3
Congress, J.L.4
Gallicano, G.I.5
-
24
-
-
10744225271
-
Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors
-
C.R. Antonescu, G. Sommer, and L. Sarran Association of KIT exon 9 mutations with nongastric primary site and aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors Clin Cancer Res 9 2003 3329 3337
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3329-3337
-
-
Antonescu, C.R.1
Sommer, G.2
Sarran, L.3
-
25
-
-
34249085905
-
Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: Proposal of new computed tomography response criteria
-
H. Choi, C. Charnsangavej, and S.C. Faria Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria J Clin Oncol 25 2007 1753 1759
-
(2007)
J Clin Oncol
, vol.25
, pp. 1753-1759
-
-
Choi, H.1
Charnsangavej, C.2
Faria, S.C.3
-
26
-
-
2542462086
-
Gene expression in gastrointestinal stromal tumors is distinguished by KIT genotype and anatomic site
-
C.R. Antonescu, A. Viale, and L. Sarran Gene expression in gastrointestinal stromal tumors is distinguished by KIT genotype and anatomic site Clin Cancer Res 10 2004 3282 3290
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3282-3290
-
-
Antonescu, C.R.1
Viale, A.2
Sarran, L.3
-
27
-
-
79952200104
-
EWSR1-POU5F1 fusion in soft tissue myoepithelial tumors. A molecular analysis of sixty-six cases, including soft tissue, bone, and visceral lesions, showing common involvement of the EWSR1 gene
-
C.R. Antonescu, L. Zhang, and N.E. Chang EWSR1-POU5F1 fusion in soft tissue myoepithelial tumors. A molecular analysis of sixty-six cases, including soft tissue, bone, and visceral lesions, showing common involvement of the EWSR1 gene Genes Chromosomes Cancer 49 2010 1114 1124
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 1114-1124
-
-
Antonescu, C.R.1
Zhang, L.2
Chang, N.E.3
-
28
-
-
0031955116
-
Consed: A graphical tool for sequence finishing
-
D. Gordon, C. Abajian, and P Green Consed: a graphical tool for sequence finishing Genome Res 8 1998 195 202
-
(1998)
Genome Res
, vol.8
, pp. 195-202
-
-
Gordon, D.1
Abajian, C.2
Green, P.3
-
29
-
-
0030872838
-
PolyPhred: Automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing
-
D.A. Nickerson, V.O. Tobe, and S.L. Taylor PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based resequencing Nucleic Acids Res 25 1997 2745 2751
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2745-2751
-
-
Nickerson, D.A.1
Tobe, V.O.2
Taylor, S.L.3
-
31
-
-
0025254076
-
Purification and properties of a novel insulin-like growth factor-II binding protein from transformed human fibroblasts
-
J.L. Martin, K.E. Willetts, and R.C. Baxter Purification and properties of a novel insulin-like growth factor-II binding protein from transformed human fibroblasts J Biol Chem 265 1990 4124 4130
-
(1990)
J Biol Chem
, vol.265
, pp. 4124-4130
-
-
Martin, J.L.1
Willetts, K.E.2
Baxter, R.C.3
-
32
-
-
0032899625
-
Insulin-like growth factor binding protein-6: The "forgotten" binding protein?
-
L.A. Bach Insulin-like growth factor binding protein-6: the "forgotten" binding protein? Horm Metab Res 31 1999 226 234
-
(1999)
Horm Metab Res
, vol.31
, pp. 226-234
-
-
Bach, L.A.1
-
33
-
-
0034618387
-
Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells
-
N. Sueoka, H.Y. Lee, and S. Wiehle Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells Oncogene 19 2000 4432 4436
-
(2000)
Oncogene
, vol.19
, pp. 4432-4436
-
-
Sueoka, N.1
Lee, H.Y.2
Wiehle, S.3
-
34
-
-
0035961991
-
Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells
-
S.L. Leng, K.S. Leeding, R.H. Whitehead, and L.A. Bach Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells Mol Cell Endocrinol 174 2001 121 127
-
(2001)
Mol Cell Endocrinol
, vol.174
, pp. 121-127
-
-
Leng, S.L.1
Leeding, K.S.2
Whitehead, R.H.3
Bach, L.A.4
-
35
-
-
18944378092
-
Insulin-like growth factor binding protein-6 inhibits prostate cancer cell proliferation: Implication for anticancer effect of diethylstilbestrol in hormone refractory prostate cancer
-
H. Koike, K. Ito, Y. Takezawa, T. Oyama, H. Yamanaka, and K. Suzuki Insulin-like growth factor binding protein-6 inhibits prostate cancer cell proliferation: implication for anticancer effect of diethylstilbestrol in hormone refractory prostate cancer Br J Cancer 92 2005 1538 1544
-
(2005)
Br J Cancer
, vol.92
, pp. 1538-1544
-
-
Koike, H.1
Ito, K.2
Takezawa, Y.3
Oyama, T.4
Yamanaka, H.5
Suzuki, K.6
-
36
-
-
0032522834
-
Expression of insulin-like growth factor-binding protein 6 complementary DNA alters neuroblastoma cell growth
-
P. Grellier, B. De Galle, and S. Babajko Expression of insulin-like growth factor-binding protein 6 complementary DNA alters neuroblastoma cell growth Cancer Res 58 1998 1670 1676
-
(1998)
Cancer Res
, vol.58
, pp. 1670-1676
-
-
Grellier, P.1
De Galle, B.2
Babajko, S.3
-
37
-
-
0035545830
-
Overexpression of insulin-like growth factor binding protein-6 inhibits rhabdomyosarcoma growth in vivo
-
M.A. Gallicchio, M. Kneen, C. Hall, A.M. Scott, and L.A. Bach Overexpression of insulin-like growth factor binding protein-6 inhibits rhabdomyosarcoma growth in vivo Int J Cancer 94 2001 645 651
-
(2001)
Int J Cancer
, vol.94
, pp. 645-651
-
-
Gallicchio, M.A.1
Kneen, M.2
Hall, C.3
Scott, A.M.4
Bach, L.A.5
-
38
-
-
0037158893
-
Differentially expressed genes associated with mouse lung tumor progression
-
R. Yao, Y. Wang, R.A. Lubet, and M. You Differentially expressed genes associated with mouse lung tumor progression Oncogene 21 2002 5814 5821
-
(2002)
Oncogene
, vol.21
, pp. 5814-5821
-
-
Yao, R.1
Wang, Y.2
Lubet, R.A.3
You, M.4
-
40
-
-
0034114584
-
Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long-distance gene regulation
-
H.K. Sasaki, K. Ishihara, and R. Kato Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long-distance gene regulation Journal of Biochemistry 127 2000 711
-
(2000)
Journal of Biochemistry
, vol.127
, pp. 711
-
-
Sasaki, H.K.1
Ishihara, K.2
Kato, R.3
-
41
-
-
0037213555
-
H19 and Igf2-enhancing the confusion?
-
K.L. Arney H19 and Igf2-enhancing the confusion? Trends in Genetics 19 2003 17 23
-
(2003)
Trends in Genetics
, vol.19
, pp. 17-23
-
-
Arney, K.L.1
-
42
-
-
0346887202
-
Mechanisms of insulator function in gene regulation and genomic imprinting
-
N. Engel, and M.S. Bartolomei Mechanisms of insulator function in gene regulation and genomic imprinting International review of cytology 232 2003 89 127
-
(2003)
International Review of Cytology
, vol.232
, pp. 89-127
-
-
Engel, N.1
Bartolomei, M.S.2
-
43
-
-
3543018516
-
Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops
-
A. Murrell, S. Heeson, and W. Reik Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops Nature genetics 36 2004 889 893
-
(2004)
Nature Genetics
, vol.36
, pp. 889-893
-
-
Murrell, A.1
Heeson, S.2
Reik, W.3
-
44
-
-
0034713375
-
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
-
A.C. Bell, and G. Felsenfeld Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene Nature 405 2000 482 485
-
(2000)
Nature
, vol.405
, pp. 482-485
-
-
Bell, A.C.1
Felsenfeld, G.2
-
45
-
-
0034713275
-
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
-
A.T. Hark, C.J. Schoenherr, D.J. Katz, R.S. Ingram, J.M. Levorse, and S.M. Tilghman CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus Nature 405 2000 486 489
-
(2000)
Nature
, vol.405
, pp. 486-489
-
-
Hark, A.T.1
Schoenherr, C.J.2
Katz, D.J.3
Ingram, R.S.4
Levorse, J.M.5
Tilghman, S.M.6
-
46
-
-
0034644120
-
Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
-
C. Kanduri, V. Pant, and D. Loukinov Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive Current Biology 10 2000 853 856
-
(2000)
Current Biology
, vol.10
, pp. 853-856
-
-
Kanduri, C.1
Pant, V.2
Loukinov, D.3
-
47
-
-
36348970734
-
Examination of IGF2 and H19 loss of imprinting in bladder cancer
-
H.M. Byun, H.L. Wong, E.A. Birnstein, E.M. Wolff, G. Liang, and A.S. Yang Examination of IGF2 and H19 loss of imprinting in bladder cancer Cancer Res 67 2007 10753 10758
-
(2007)
Cancer Res
, vol.67
, pp. 10753-10758
-
-
Byun, H.M.1
Wong, H.L.2
Birnstein, E.A.3
Wolff, E.M.4
Liang, G.5
Yang, A.S.6
-
48
-
-
71049127914
-
Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro
-
J.J. Dupart, J.C. Trent, and H.Y. Lee Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro Mol Cancer 8 2009 99
-
(2009)
Mol Cancer
, vol.8
, pp. 99
-
-
Dupart, J.J.1
Trent, J.C.2
Lee, H.Y.3
|