Non-islet cell tumour hypoglycaemia in a patient with a gastrointestinal stromal tumour [1]

Acta Oncologica

Volumn 44, Issue 7, 2005, Pages 764-766

  Rikhof, Bart ^a   Van Den Berg, Gerrit ^a   Van Der Graaf, Winette T A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; IMATINIB; PREDNISOLONE; SOMATOMEDIN B;

ADULT; CASE REPORT; CLINICAL FEATURE; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); DISEASE COURSE; FOLLOW UP; GASTROINTESTINAL STROMAL TUMOR; HUMAN; HYPOGLYCEMIA; LETTER; MALE; PHASE 1 CLINICAL TRIAL; PHYSICAL EXAMINATION; PRIORITY JOURNAL; TREATMENT FAILURE;

GASTROINTESTINAL STROMAL TUMORS; HUMANS; HYPOGLYCEMIA; INSULIN-LIKE GROWTH FACTOR II; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS;

EID: 27544483546     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02841860500267816     Document Type: Letter

References (23)

1. Service FJ. Hypoglycemic disorders. N Engl J Med 1995; 332:1144-52.
2. Marks V, Teale JD. Tumours producing hypoglycaemia. Endocr Relat Cancer 1998;5:111-29.
3. Le Roith D. Tumor-induced hypoglycemie. N Engl J Med 1999;341:757-8.
4. Rinderknecht E, Humbel RE. Primary structure of human insulin-like growth factor II. FEBS Lett 1978;89:283-6.
5. Rinderknecht E, Humbel RE. The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J Biol Chem 1978;253:2769-76.
6. Phillips LS, Robertson DG. Insulin-like growth factors and non-islet cell tumor hypoglycemia. Metabolism 1993;42: 1093-101.
7. Rajaram S, Baylink DJ, Mohan S. Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. Endocr Rev 1997;18:801-31.
8. Daughaday WH. The possible autocrine/paracrine and endocrine roles of insulin-like growth factors of human tumors. Endocrinology 1990;127:1-4.
9. Zapf J, Futo E, Peter M, Froesch ER. Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia? J Clin Invest 1992;90:2574-84.
10. El-Badry OM, Minniti C, Kohn EC, Houghton PJ, Daughaday WH, Herman LJ. Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth Differ 1990;1: 325-31.
11. Van Doom J, Hoogerbrugge CM, Koster JG, Bloemen RJ, Hoekman K, Mudde AH, et al. Antibodies directed against the E region of pro-insulin-like growth factor-II used to evaluate non-islet cell tumor-induced hypoglycemia. Clin Chem 2002;48:1739-50.
12. Daughaday WH, Kapadia M. Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumors. Proc Natl Acad Sci USA 1989;86:6778-82.
13. Baxter RC, Daughaday WH. Impaired formation of the ternary insulin-like growth factor-binding protein complex in patients with hypoglycemia due to nonislet cell tumors. J Clin Endocrinol Metab 1991;73:696-702.
14. Eastman RC, Carson RE, Orloff DG, Cochran CS, Perdue JF, Rechler MM. Glucose utilization in a patient with hepatoma and hypoglycemia. Assessment by a positron emission tomography. J Clin Invest 1992;89:1958-63.
15. Zapf J, Schmid C, Guler HP, Waldvogel M, Hauri C, Futo E, et al. Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia. J Clin Invest 1990;86:952-61.
16. Corless CL, Fletcher JA, Heinrich MC. Biology of gastrointestinal stromal tumors. J Clin Oncol 2004;22:3813-25.
17. Verweij J, Van Oosterom A, Blay JY, Judson I, Rodenhuis S, Van der Graaf W, et al. Imatinib mesylate (STI-571 Glivec®, Gleevec™) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target: Results from an EORTC soft tissue and bone sarcoma group phase II study. Eur J Cancer 2003;39:2006-11.
18. Beckers MM, Slee PH, Van Doom J. Hypoglycaemia in a patient with a gastrointestinal stromal tumour. Clin Endocrinol (Oxf) 2003;59:402-4.
19. Baig M, Hintz RL, Baker BK, Vesely DL. Hypoglycemia attributable to insulin-like growth factor-II prohormone-producing metastatic leiomyosarcoma. Endocr Pract 1999;5: 37-42.
20. Riccioni N, Donati G, Navalesi R. Hypoglycemia associated with a leiomyosarcoma of the small bowel. Acta Diabetol Lat 1981;18:275-81.
21. Teale JD, Marks V. Glucocorticoid therapy suppresses abnormal secretion of big IGF-II by non-islet cell tumours inducing hypoglycaemia (NICTH). Clin Endocrinol (Oxf) 1998;49:491-8.
22. Baxter RC, Holman SR, Corbould A, Stranks S, Ho PJ, Braund W. Regulation of the insulin-like growth factors and their binding proteins by glucocorticoid and growth hormone in nonislet cell tumor hypoglycemia. J Clin Endocrinol Metab 1995;80:2700-8.
23. Hoff AO, Vassilopoulou-Sellin R. The role of glucagon administration in the diagnosis and treatment of patients with tumor hypoglycemia. Cancer 1998;82:1585-92.