-
1
-
-
15644363454
-
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
-
Hirota S, Isozaki K, Moriyama Y et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998; 279: 577-580.
-
(1998)
Science
, vol.279
, pp. 577-580
-
-
Hirota, S.1
Isozaki, K.2
Moriyama, Y.3
-
2
-
-
0242670019
-
PDGFRA activating mutations in gastrointestinal stromal tumors
-
Heinrich MC, Corless CL, Duensing A et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science 2003; 299: 708-710.
-
(2003)
Science
, vol.299
, pp. 708-710
-
-
Heinrich, M.C.1
Corless, C.L.2
Duensing, A.3
-
3
-
-
34848883114
-
KIT oncoprotein interactions in gastrointestinal stromal tumors: Therapeutic relevance
-
Zhu MJ, Ou WB, Fletcher CD et al. KIT oncoprotein interactions in gastrointestinal stromal tumors: Therapeutic relevance. Oncogene 2007; 26: 6386-6395.
-
(2007)
Oncogene
, vol.26
, pp. 6386-6395
-
-
Zhu, M.J.1
Ou, W.B.2
Fletcher, C.D.3
-
4
-
-
0034692430
-
Role of the insulin-like growth factor family in cancer development and progression
-
Yu H, Rohan T, Role of the insulin-like growth factor family in cancer development and progression. J Natl Cancer Inst 2000; 92: 1472-1489.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1472-1489
-
-
Yu, H.1
Rohan, T.2
-
5
-
-
0034729152
-
Loss of IGF-II imprinting in endometrial tumors: Overexpression in carcinosarcoma
-
Roy RN, Gerulath AH, Cecutti A, Bhavnani BR. Loss of IGF-II imprinting in endometrial tumors: Overexpression in carcinosarcoma. Cancer Lett 2000; 153: 67-73.
-
(2000)
Cancer Lett
, vol.153
, pp. 67-73
-
-
Roy, R.N.1
Gerulath, A.H.2
Cecutti, A.3
Bhavnani, B.R.4
-
6
-
-
0034974302
-
IGF-I receptor signalling in transformation and differentiation
-
Valentinis B, Baserga R. IGF-I receptor signalling in transformation and differentiation. Mol Pathol 2001; 54: 133-137.
-
(2001)
Mol Pathol
, vol.54
, pp. 133-137
-
-
Valentinis, B.1
Baserga, R.2
-
7
-
-
1942436958
-
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: Systematic review and meta-regression analysis
-
Renehan AG, Zwahlen M, Minder C et al. Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: Systematic review and meta-regression analysis. Lancet 2004; 363: 1346-1353.
-
(2004)
Lancet
, vol.363
, pp. 1346-1353
-
-
Renehan, A.G.1
Zwahlen, M.2
Minder, C.3
-
8
-
-
33745726110
-
Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer
-
Severi G, Morris HA, MacInnis RJ et al. Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev 2006; 15: 1137-1141.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 1137-1141
-
-
Severi, G.1
Morris, H.A.2
MacInnis, R.J.3
-
9
-
-
34247534611
-
Circulating insulin-like growth factor-I and binding protein-3 and the risk of breast cancer
-
Baglietto L, English DR, Hopper JL et al. Circulating insulin-like growth factor-I and binding protein-3 and the risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2007; 16: 763-768.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 763-768
-
-
Baglietto, L.1
English, D.R.2
Hopper, J.L.3
-
10
-
-
34250887614
-
Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: Results from the European Prospective Investigation into Cancer and Nutrition
-
Allen NE, Key TJ, Appleby PN et al. Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: Results from the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev 2007; 16: 1121-1127.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 1121-1127
-
-
Allen, N.E.1
Key, T.J.2
Appleby, P.N.3
-
11
-
-
35348831817
-
IGF-1 and IGFBP-3: Risk of prostate cancer among men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
-
Weiss JM, Huang WY, Rinaldi S et al. IGF-1 and IGFBP-3: Risk of prostate cancer among men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Int J Cancer 2007; 121: 2267-2273
-
(2007)
Int J Cancer
, vol.121
, pp. 2267-2273
-
-
Weiss, J.M.1
Huang, W.Y.2
Rinaldi, S.3
-
12
-
-
33947221074
-
Plasma C-peptide, insulin-like growth factor-I, insulin-like growth factor binding proteins and risk of colorectal cancer in a nested case-control study: The Japan public health center-based prospective study
-
Otani T, Iwasaki M, Sasazuki S et al. Plasma C-peptide, insulin-like growth factor-I, insulin-like growth factor binding proteins and risk of colorectal cancer in a nested case-control study: The Japan public health center-based prospective study. Int J Cancer 2007; 120: 2007-2012.
-
(2007)
Int J Cancer
, vol.120
, pp. 2007-2012
-
-
Otani, T.1
Iwasaki, M.2
Sasazuki, S.3
-
13
-
-
39149111599
-
Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women
-
Gunter MJ, Hoover DR, Yu H et al. Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women. Cancer Res 2008; 68: 329-337.
-
(2008)
Cancer Res
, vol.68
, pp. 329-337
-
-
Gunter, M.J.1
Hoover, D.R.2
Yu, H.3
-
14
-
-
16444376296
-
A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women
-
Wei EK, Ma J, Pollak MN et al. A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women. Cancer Epidemiol Biomarkers Prev 2005; 14: 850-855.
-
(2005)
Cancer Epidemiol Biomarkers Prev
, vol.14
, pp. 850-855
-
-
Wei, E.K.1
Ma, J.2
Pollak, M.N.3
-
15
-
-
0033531765
-
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
-
Ma J, Pollak MN, Giovannucci E et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst 1999; 91: 620-625.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 620-625
-
-
Ma, J.1
Pollak, M.N.2
Giovannucci, E.3
-
16
-
-
10744228945
-
Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway
-
Sekharam M, Zhao H, Sun M et al. Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway. Cancer Res 2003; 63: 7708-7716.
-
(2003)
Cancer Res
, vol.63
, pp. 7708-7716
-
-
Sekharam, M.1
Zhao, H.2
Sun, M.3
-
17
-
-
36348994146
-
Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells
-
Shi B, Sepp-Lorenzino L, Prisco M et al. Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem 2007; 282: 32582-32590.
-
(2007)
J Biol Chem
, vol.282
, pp. 32582-32590
-
-
Shi, B.1
Sepp-Lorenzino, L.2
Prisco, M.3
-
18
-
-
36849055249
-
Colon-carcinogenesis in liver-specific IGF-I-deficient (LID) mice
-
Ealey KN, Xuan W, Lu S, Archer MC. Colon-carcinogenesis in liver-specific IGF-I-deficient (LID) mice. Int J Cancer 2008; 122: 472-476.
-
(2008)
Int J Cancer
, vol.122
, pp. 472-476
-
-
Ealey, K.N.1
Xuan, W.2
Lu, S.3
Archer, M.C.4
-
19
-
-
33846817099
-
-
Escobar GA, Robinson WA, Nydam TL et al. Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: A case report. BMG Cancer 2007; 7: 13.
-
Escobar GA, Robinson WA, Nydam TL et al. Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: A case report. BMG Cancer 2007; 7: 13.
-
-
-
-
20
-
-
33846939042
-
Hypoglycemia in the setting of advanced gastrointestinal stromal tumor
-
Guiteau J, Fanucchi M, Folpe A et al. Hypoglycemia in the setting of advanced gastrointestinal stromal tumor. Am Surg 2006; 72: 1225-1230.
-
(2006)
Am Surg
, vol.72
, pp. 1225-1230
-
-
Guiteau, J.1
Fanucchi, M.2
Folpe, A.3
-
21
-
-
33748092018
-
Clinical features of insulin-liKe growth factor-II producing non-islet-cell tumor hypoglycemia
-
Fukuda I, Hizuka N, Ishikawa Y et al. Clinical features of insulin-liKe growth factor-II producing non-islet-cell tumor hypoglycemia. Growth Horm IGF Res. 2006; 16: 211-216.
-
(2006)
Growth Horm IGF Res
, vol.16
, pp. 211-216
-
-
Fukuda, I.1
Hizuka, N.2
Ishikawa, Y.3
-
22
-
-
33745525270
-
Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinip
-
Hamberg P, de Jong FA, Boonstra JG et al. Non-islet-cell tumor induced hypoglycemia in patients with advanced gastrointestinal stromal tumor possibly worsened by imatinip. J Clin Oncol 2006; 24: E30-e31.
-
(2006)
J Clin Oncol
, vol.24
-
-
Hamberg, P.1
de Jong, F.A.2
Boonstra, J.G.3
-
23
-
-
33144469823
-
Non-hyperinsulinemic hypoglycemia in a patient with a gastrointestinal stromal tumor
-
Singh R, Grey A, Miller M et al. Non-hyperinsulinemic hypoglycemia in a patient with a gastrointestinal stromal tumor. Eur J Intern Med 2006; 17: 127-129.
-
(2006)
Eur J Intern Med
, vol.17
, pp. 127-129
-
-
Singh, R.1
Grey, A.2
Miller, M.3
-
24
-
-
27544483546
-
Non-islet cell tumour hypoglycaemia in a patient with a gastrointestinal stromal tumour
-
Rikhof B, Van Den BG. Van Der Graaf WT. Non-islet cell tumour hypoglycaemia in a patient with a gastrointestinal stromal tumour. Acta Oncol 2005; 44: 764-766.
-
(2005)
Acta Oncol
, vol.44
, pp. 764-766
-
-
Rikhof, B.V.D.B.1
Van Der2
Graaf, W.T.3
-
25
-
-
27244442412
-
Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: A report of two cases
-
Pink D, Schoeler D, Lindner T et al. Severe hypoglycemia caused by paraneoplastic production of IGF-II in patients with advanced gastrointestinal stromal tumors: A report of two cases. J Clin Oncol 2005; 23: 6809-6811.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6809-6811
-
-
Pink, D.1
Schoeler, D.2
Lindner, T.3
-
26
-
-
4444284454
-
Free insulin-like growth factors - measurements and relationships to growth hormone secretion and glucose homeostasis
-
Frystyk J. Free insulin-like growth factors - measurements and relationships to growth hormone secretion and glucose homeostasis. Growth Horm IGF Res 2004; 14: 337-375.
-
(2004)
Growth Horm IGF Res
, vol.14
, pp. 337-375
-
-
Frystyk, J.1
-
27
-
-
0036301722
-
Diagnosis of gastrointestinal stromal tumors: A consensus approach
-
Fletcher CD, Berman JJ, Corless C et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002; 33: 459-465.
-
(2002)
Hum Pathol
, vol.33
, pp. 459-465
-
-
Fletcher, C.D.1
Berman, J.J.2
Corless, C.3
-
28
-
-
34249791491
-
Adjuvant imatinib treatment improves recurrence-free survival in patients with high-risk gastrointestinal stromal tumours (GIST)
-
Nilsson B, Sjolund K, Kindblom LG et al. Adjuvant imatinib treatment improves recurrence-free survival in patients with high-risk gastrointestinal stromal tumours (GIST). Br J Cancer 2007; 96: 1656-1658.
-
(2007)
Br J Cancer
, vol.96
, pp. 1656-1658
-
-
Nilsson, B.1
Sjolund, K.2
Kindblom, L.G.3
-
29
-
-
34247339427
-
Prognostic significance of angiogenesis in gastrointestinal stromal tumor
-
Imamura M, Yamamoto H, Nakamura N et al. Prognostic significance of angiogenesis in gastrointestinal stromal tumor. Mod Pathol 2007; 20: 529-537.
-
(2007)
Mod Pathol
, vol.20
, pp. 529-537
-
-
Imamura, M.1
Yamamoto, H.2
Nakamura, N.3
-
30
-
-
0344375087
-
Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach
-
Takahashi R, Tanaka S, Kitadai Y et al. Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach. Oncology 2003; 64: 266-274.
-
(2003)
Oncology
, vol.64
, pp. 266-274
-
-
Takahashi, R.1
Tanaka, S.2
Kitadai, Y.3
-
31
-
-
0142175222
-
Hypoxia-inducible tactor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach
-
Takahashi R, Tanaka S, Hiyama T et al. Hypoxia-inducible tactor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach. Oncol Rep 2003; 10: 797-802.
-
(2003)
Oncol Rep
, vol.10
, pp. 797-802
-
-
Takahashi, R.1
Tanaka, S.2
Hiyama, T.3
-
32
-
-
33745615848
-
Insulin-like growth factor receptor 1 (IGER-1) is significantly associated with longer survival in non-small-cell lung cancer patents treated with gefitinib
-
Cappuzzo F, Toschi L, Tallini G et al. Insulin-like growth factor receptor 1 (IGER-1) is significantly associated with longer survival in non-small-cell lung cancer patents treated with gefitinib. Ann Oncol 2006; 17: 1120-1127.
-
(2006)
Ann Oncol
, vol.17
, pp. 1120-1127
-
-
Cappuzzo, F.1
Toschi, L.2
Tallini, G.3
-
33
-
-
34848834225
-
Insulin receptor is an independent predictor of a favorable outcome in early stage breast cancer
-
Mulligan AM, O'malley FP, Ennis M et al. Insulin receptor is an independent predictor of a favorable outcome in early stage breast cancer. Breast Cancer Res Treat 2007; 106: 36-46.
-
(2007)
Breast Cancer Res Treat
, vol.106
, pp. 36-46
-
-
Mulligan, A.M.1
O'malley, F.P.2
Ennis, M.3
-
34
-
-
0345392848
-
Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-1) expression in prostatic cancer
-
Cardillo MR, Monti S, Di SF et al. Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-1) expression in prostatic cancer. Anticancer Res 2003; 23: 3825-3835.
-
(2003)
Anticancer Res
, vol.23
, pp. 3825-3835
-
-
Cardillo, M.R.1
Monti, S.2
Di, S.F.3
-
35
-
-
0033617446
-
Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways
-
Valentinis B, Romano G, Peruzzi F et al. Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways. J Biol Chem 1999; 274: 12423-12430.
-
(1999)
J Biol Chem
, vol.274
, pp. 12423-12430
-
-
Valentinis, B.1
Romano, G.2
Peruzzi, F.3
-
36
-
-
11344254328
-
Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma
-
Ahlen J, Wejde J, Brosjo O et al. Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma. Clin Cancer Res 2005; 11: 206-216.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 206-216
-
-
Ahlen, J.1
Wejde, J.2
Brosjo, O.3
-
37
-
-
33744903660
-
Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms
-
Tam C, Skorobogatko YV, Taguchi T et al. Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms. Cancer Res 2006; 66: 5477-5486.
-
(2006)
Cancer Res
, vol.66
, pp. 5477-5486
-
-
Tam, C.1
Skorobogatko, Y.V.2
Taguchi, T.3
-
38
-
-
32844458682
-
GISTs with POGFRA exon 14 mutations represent subset of clinically favorable gastric tumors with epithelioid morphology
-
Lasota J, Stachura J, Miettinen M. GISTs with POGFRA exon 14 mutations represent subset of clinically favorable gastric tumors with epithelioid morphology. Lab Invest 2006; 86: 94-100.
-
(2006)
Lab Invest
, vol.86
, pp. 94-100
-
-
Lasota, J.1
Stachura, J.2
Miettinen, M.3
-
39
-
-
41549165611
-
KIT and PDGFR [alpha] mutations in 104 patients with gastrointestinal stromal tumors (GISTs): A population-based study
-
Jan 10, Epud ahead of printing
-
Braconi C, Bracci R, Bearzi I et al. KIT and PDGFR [alpha] mutations in 104 patients with gastrointestinal stromal tumors (GISTs): A population-based study. Ann Oncol 2008, Jan 10, Epud ahead of printing.
-
(2008)
Ann Oncol
-
-
Braconi, C.1
Bracci, R.2
Bearzi, I.3
-
40
-
-
33947262154
-
Preclinical in vivo study of new insulin-like growth factor-1 receptor-specific inhibitor in Ewing's sarcoma
-
Manara MC, Landuzzi L, Nanni P et al. Preclinical in vivo study of new insulin-like growth factor-1 receptor-specific inhibitor in Ewing's sarcoma. Clin Cancer Res 2007; 13: 1322-1330.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1322-1330
-
-
Manara, M.C.1
Landuzzi, L.2
Nanni, P.3
|