Excipient effects on humanized monoclonal antibody interactions with silicone oil emulsions

Journal of Pharmaceutical Sciences

Volumn 101, Issue 12, 2012, Pages 4419-4432

  Britt, Keith A ^a   Schwartz, Daniel K ^a   Wurth, Christine ^b   Mahler, Hanns Christian ^b   Carpenter, John F ^c   Randolph, Theodore W ^a  

^a UCB 450   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Adsorption; Colloidal stability; Emulsion; Fluorescence spectroscopy; Macromolecular drug delivery; Non ionic surfactants; Physical stability; Protein aggregation; Protein formulation; Silicone oil

Indexed keywords

EID: 84868194244     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23318     Document Type: Article

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