Protein adsorption and excipient effects on kinetic stability of silicone oil emulsions

Journal of Pharmaceutical Sciences

Volumn 99, Issue 4, 2010, Pages 1721-1733

  Brett Ludwig, D ^a,b   Carpenter, John F ^a,c   Hamel, Jean Bernard ^d   Randolph, Theodore W ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b University of Colorado at Boulder   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d BD Medical Pharmaceutical Systems   (France)

Author keywords

Adsorption; Colloidal stability; Excipients; Formulation; Protein aggregation; Silicone oil

Indexed keywords

ABATACEPT; BOVINE SERUM ALBUMIN; EXCIPIENT; LYSOZYME; SILICONE OIL; SODIUM CHLORIDE; SUCROSE; SURFACTANT; TRASTUZUMAB; WATER OIL CREAM;

ADSORPTION; ARTICLE; DRUG STABILITY; KINETICS; PARTICLE SIZE; PROTEIN ADSORPTION; PROTEIN DEPLETION; PROTEIN STABILITY; SURFACE CHARGE; SUSPENSION;

EID: 77949821607     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21982     Document Type: Article

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