Identification of the NAD(P)H binding site of eukaryotic UDP-galactopyranose mutase

Journal of the American Chemical Society

Volumn 134, Issue 43, 2012, Pages 18132-18138

  Dhatwalia, Richa ^a   Singh, Harkewal ^a   Solano, Luis M ^c   Oppenheimer, Michelle ^d   Robinson, Reeder M ^d   Ellerbrock, Jacob F ^d   Sobrado, Pablo ^d   Tanner, John J ^a,b  

^a UNIVERSITY OF MISSOURI   (United States)

^b University of Missouri   (United States)

^c INSTITUTO TECNOLÓGICO DE COSTA RICA   (Costa Rica)

^d VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ANTI-FUNGAL; ASPERGILLUS FUMIGATUS; DRUG DISCOVERY; GALACTOFURANOSE; GALACTOPYRANOSE; NAD(P)H; PROTEIN CRYSTALLOGRAPHY; REDOX PARTNERS; SUBSTRATE BINDING; UDP-GALACTOPYRANOSE;

AMIDES; ASPERGILLUS; BINDING SITES; CRYSTALLOGRAPHY;

BACTERIA;

ADENOSINE DIPHOSPHATE; FLAVINE ADENINE NUCLEOTIDE; GALACTOPYRANOSE; GALACTOSE; MUTASE; NICOTINAMIDE; NICOTINAMIDE RIBOSIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UDP GALACTOPYRANOSE MUTASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GALACTOSE;

ARTICLE; ASPERGILLUS FUMIGATUS; BACTERIUM; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE; EUKARYOTE; FUNGAL STRAIN; KINETICS; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN BINDING; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

ASPERGILLUS FUMIGATUS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; INTRAMOLECULAR TRANSFERASES; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NADP; OXIDATION-REDUCTION;

EID: 84868152802     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja308188z     Document Type: Article

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