-
1
-
-
0030922920
-
Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines
-
Allen, P. B., Ouimet, C. C., and Greengard, P. (1997) Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc. Natl. Acad. Sci. U. S. A. 94, 9956-9961
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 9956-9961
-
-
Allen, P.B.1
Ouimet, C.C.2
Greengard, P.3
-
2
-
-
33748770348
-
Spinophilin: From partners to functions
-
Sarrouilhe, D., di Tommaso, A., Metaye, T., and Ladeveze, V. (2006) Spinophilin: from partners to functions. Biochimie (Paris) 88, 1099-1113
-
(2006)
Biochimie (Paris)
, vol.88
, pp. 1099-1113
-
-
Sarrouilhe, D.1
Di Tommaso, A.2
Metaye, T.3
Ladeveze, V.4
-
3
-
-
34249999458
-
Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors
-
Wang, X., Zeng, W., Kim, M. S., Allen, P. B., Greengard, P., and Muallem, S. (2007) Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors. EMBO J. 26, 2768-2776
-
(2007)
EMBO J.
, vol.26
, pp. 2768-2776
-
-
Wang, X.1
Zeng, W.2
Kim, M.S.3
Allen, P.B.4
Greengard, P.5
Muallem, S.6
-
4
-
-
69549130897
-
Effects of spinophilin on the function of RGS8 regulating signals from M2 and M3-mAChRs
-
Kurogi, M., Nagatomo, K., Kubo, Y., and Saitoh, O. (2009) Effects of spinophilin on the function of RGS8 regulating signals from M2 and M3-mAChRs. Neuroreport 20, 1134-1139
-
(2009)
Neuroreport
, vol.20
, pp. 1134-1139
-
-
Kurogi, M.1
Nagatomo, K.2
Kubo, Y.3
Saitoh, O.4
-
7
-
-
3042659111
-
Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors
-
Wang, Q., Zhao, J., Brady, A. E., Feng, J., Allen, P. B., Lefkowitz, R. J., Greengard, P., and Limbird, L. E. (2004) Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors. Science 304, 1940-1944
-
(2004)
Science
, vol.304
, pp. 1940-1944
-
-
Wang, Q.1
Zhao, J.2
Brady, A.E.3
Feng, J.4
Allen, P.B.5
Lefkowitz, R.J.6
Greengard, P.7
Limbird, L.E.8
-
8
-
-
0037184945
-
Regulated interactions of the alpha 2A adrenergic receptor with spinophilin, 14-3-3zeta, and arrestin 3
-
Wang, Q., and Limbird, L. E. (2002) Regulated interactions of the alpha 2A adrenergic receptor with spinophilin, 14-3-3zeta, and arrestin 3. J. Biol. Chem. 277, 50589-50596
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50589-50596
-
-
Wang, Q.1
Limbird, L.E.2
-
9
-
-
33751533776
-
New roles for beta-arrestins in cell signaling: Not just for seven-transmembrane receptors
-
Lefkowitz, R. J., Rajagopal, K., and Whalen, E. J. (2006) New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors. Mol. Cell 24, 643-652
-
(2006)
Mol. Cell
, vol.24
, pp. 643-652
-
-
Lefkowitz, R.J.1
Rajagopal, K.2
Whalen, E.J.3
-
10
-
-
77952415656
-
Beyond desensitization: Physiological relevance of arrestin-dependent signaling
-
Luttrell, L. M., and Gesty-Palmer, D. (2010) Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol. Rev. 62, 305-330
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 305-330
-
-
Luttrell, L.M.1
Gesty-Palmer, D.2
-
11
-
-
17344367802
-
2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors
-
2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors. Nat. Cell Biol. 7, 405-411
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 405-411
-
-
Wang, X.1
Zeng, W.2
Soyombo, A.A.3
Tang, W.4
Ross, E.M.5
Barnes, A.P.6
Milgram, S.L.7
Penninger, J.M.8
Allen, P.B.9
Greengard, P.10
Muallem, S.11
-
12
-
-
42149131142
-
Multiple actions of spinophilin regulate mu opioid receptor function
-
Charlton, J. J., Allen, P. B., Psifogeorgou, K., Chakravarty, S., Gomes, I., Neve, R. L., Devi, L. A., Greengard, P., Nestler, E. J., and Zachariou, V. (2008) Multiple actions of spinophilin regulate mu opioid receptor function. Neuron 58, 238-247
-
(2008)
Neuron
, vol.58
, pp. 238-247
-
-
Charlton, J.J.1
Allen, P.B.2
Psifogeorgou, K.3
Chakravarty, S.4
Gomes, I.5
Neve, R.L.6
Devi, L.A.7
Greengard, P.8
Nestler, E.J.9
Zachariou, V.10
-
13
-
-
58149350017
-
2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences
-
2- adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences. Behav. Brain Res. 197, 457-461
-
(2009)
Behav. Brain Res.
, vol.197
, pp. 457-461
-
-
Nag, S.1
Wang, Q.2
Limbird, L.E.3
Mokha, S.S.4
-
14
-
-
0029789994
-
Molecular biology of muscarinic acetylcholine receptors
-
Wess, J. (1996) Molecular biology of muscarinic acetylcholine receptors. Crit. Rev. Neurobiol. 10, 69-99
-
(1996)
Crit. Rev. Neurobiol.
, vol.10
, pp. 69-99
-
-
Wess, J.1
-
15
-
-
0034786750
-
Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function
-
Gilon, P., and Henquin, J. C. (2001) Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function. Endocr. Rev. 22, 565-604
-
(2001)
Endocr. Rev.
, vol.22
, pp. 565-604
-
-
Gilon, P.1
Henquin, J.C.2
-
16
-
-
33744510095
-
3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo
-
3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo. Cell Metab. 3, 449-461
-
(2006)
Cell Metab.
, vol.3
, pp. 449-461
-
-
Gautam, D.1
Han, S.J.2
Hamdan, F.F.3
Jeon, J.4
Li, B.5
Li, J.H.6
Cui, Y.7
Mears, D.8
Lu, H.9
Deng, C.10
Heard, T.11
Wess, J.12
-
17
-
-
78049521571
-
3 muscarinic acetylcholine receptors in transgenic mice
-
3 muscarinic acetylcholine receptors in transgenic mice. Endocrinology 151, 5185-5194
-
(2010)
Endocrinology
, vol.151
, pp. 5185-5194
-
-
Gautam, D.1
Ruiz De Azua, I.2
Li, J.H.3
Guettier, J.M.4
Heard, T.5
Cui, Y.6
Lu, H.7
Jou, W.8
Gavrilova, O.9
Zawalich, W.S.10
Wess, J.11
-
19
-
-
27744508267
-
In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: Possible involvement of lipid raft
-
Ishii, M., Ikushima, M., and Kurachi, Y. (2005) In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: possible involvement of lipid raft. Biochem. Biophys. Res. Commun. 338, 839-846
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, pp. 839-846
-
-
Ishii, M.1
Ikushima, M.2
Kurachi, Y.3
-
20
-
-
79959862379
-
Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins
-
Vishnivetskiy, S. A., Gimenez, L. E., Francis, D. J., Hanson, S. M., Hubbell, W. L., Klug, C. S., and Gurevich, V. V. (2011) Few residues within an extensive binding interface drive receptor interaction and determine the specificity of arrestin proteins. J. Biol. Chem. 286, 24288-24299
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 24288-24299
-
-
Vishnivetskiy, S.A.1
Gimenez, L.E.2
Francis, D.J.3
Hanson, S.M.4
Hubbell, W.L.5
Klug, C.S.6
Gurevich, V.V.7
-
21
-
-
0034254991
-
Spinophilin regulates the formation and function of dendritic spines
-
Feng, J., Yan, Z., Ferreira, A., Tomizawa, K., Liauw, J. A., Zhuo, M., Allen, P. B., Ouimet, C. C., and Greengard, P. (2000) Spinophilin regulates the formation and function of dendritic spines. Proc. Natl. Acad. Sci. U. S. A. 97, 9287-9292
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 9287-9292
-
-
Feng, J.1
Yan, Z.2
Ferreira, A.3
Tomizawa, K.4
Liauw, J.A.5
Zhuo, M.6
Allen, P.B.7
Ouimet, C.C.8
Greengard, P.9
-
22
-
-
0027360242
-
Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets
-
Ishihara, H., Asano, T., Tsukuda, K., Katagiri, H., Inukai, K., Anai, M., Kikuchi, M., Yazaki, Y., Miyazaki, J. I., and Oka, Y. (1993) Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia 36, 1139-1145
-
(1993)
Diabetologia
, vol.36
, pp. 1139-1145
-
-
Ishihara, H.1
Asano, T.2
Tsukuda, K.3
Katagiri, H.4
Inukai, K.5
Anai, M.6
Kikuchi, M.7
Yazaki, Y.8
Miyazaki, J.I.9
Oka, Y.10
-
24
-
-
1642535435
-
Differentially regulated expression of endogenous RGS4 and RGS7
-
Krumins, A. M., Barker, S. A., Huang, C., Sunahara, R. K., Yu, K., Wilkie, T. M., Gold, S. J., and Mumby, S. M. (2004) Differentially regulated expression of endogenous RGS4 and RGS7. J. Biol. Chem. 279, 2593-2599
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2593-2599
-
-
Krumins, A.M.1
Barker, S.A.2
Huang, C.3
Sunahara, R.K.4
Yu, K.5
Wilkie, T.M.6
Gold, S.J.7
Mumby, S.M.8
-
27
-
-
77952340101
-
RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo
-
Ruiz de Azua, I., Scarselli, M., Rosemond, E., Gautam, D., Jou, W., Gavrilova, O., Ebert, P. J., Levitt, P., and Wess, J. (2010) RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo. Proc. Natl. Acad. Sci. U. S. A. 107, 7999-8004
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 7999-8004
-
-
Ruiz De Azua, I.1
Scarselli, M.2
Rosemond, E.3
Gautam, D.4
Jou, W.5
Gavrilova, O.6
Ebert, P.J.7
Levitt, P.8
Wess, J.9
-
28
-
-
33646343978
-
Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET)
-
Pfleger, K. D., and Eidne, K. A. (2006) Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET). Nat. Meth. 3, 165-174
-
(2006)
Nat. Meth.
, vol.3
, pp. 165-174
-
-
Pfleger, K.D.1
Eidne, K.A.2
-
29
-
-
0037160105
-
Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by biolumines-cence resonance energy transfer
-
Mercier, J. F., Salahpour, A., Angers, S., Breit, A., and Bouvier, M. (2002) Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by biolumines-cence resonance energy transfer. J. Biol. Chem. 277, 44925-44931
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44925-44931
-
-
Mercier, J.F.1
Salahpour, A.2
Angers, S.3
Breit, A.4
Bouvier, M.5
-
30
-
-
77951844975
-
Teaching old receptors new tricks: Biasing seven-transmembrane receptors
-
Rajagopal, S., Rajagopal, K., and Lefkowitz, R. J. (2010) Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nat. Rev. Drug Discov. 9, 373-386
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 373-386
-
-
Rajagopal, S.1
Rajagopal, K.2
Lefkowitz, R.J.3
-
31
-
-
80052815783
-
Study of GPCR-protein interactions by BRET
-
Kocan, M., and Pfleger, K. D. (2011) Study of GPCR-protein interactions by BRET. Methods Mol. Biol. 746, 357-371
-
(2011)
Methods Mol. Biol.
, vol.746
, pp. 357-371
-
-
Kocan, M.1
Pfleger, K.D.2
-
32
-
-
43949084326
-
Recruitment of beta-arrestin2 to the dopamine D2 receptor: Insights into anti-psychotic and anti-parkinsonian drug receptor signaling
-
Klewe, I. V., Nielsen, S. M., Tarpo, L., Urizar, E., Dipace, C., Javitch, J. A., Gether, U., Egebjerg, J., and Christensen, K. V. (2008) Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling. Neuropharmacology 54, 1215-1222
-
(2008)
Neuropharmacology
, vol.54
, pp. 1215-1222
-
-
Klewe, I.V.1
Nielsen, S.M.2
Tarpo, L.3
Urizar, E.4
Dipace, C.5
Javitch, J.A.6
Gether, U.7
Egebjerg, J.8
Christensen, K.V.9
-
33
-
-
24144488192
-
High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay
-
Hamdan, F. F., Audet, M., Garneau, P., Pelletier, J., and Bouvier, M. (2005) High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay. J. Biomol. Screen. 10, 463-475
-
(2005)
J. Biomol. Screen.
, vol.10
, pp. 463-475
-
-
Hamdan, F.F.1
Audet, M.2
Garneau, P.3
Pelletier, J.4
Bouvier, M.5
-
34
-
-
44349129654
-
Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells
-
Sonoda, N., Imamura, T., Yoshizaki, T., Babendure, J. L., Lu, J. C., and Olefsky, J. M. (2008) Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells. Proc. Natl. Acad. Sci. U. S. A. 105, 6614-6619
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6614-6619
-
-
Sonoda, N.1
Imamura, T.2
Yoshizaki, T.3
Babendure, J.L.4
Lu, J.C.5
Olefsky, J.M.6
-
35
-
-
77649190704
-
Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells
-
Balasubramanian, R., Ruiz de Azua, I., Wess, J., and Jacobson, K. A. (2010) Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells. Biochem. Pharmacol. 79, 1317-1326
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 1317-1326
-
-
Balasubramanian, R.1
Ruiz De Azua, I.2
Wess, J.3
Jacobson, K.A.4
-
36
-
-
36148996843
-
G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes
-
Winzell, M. S., and Ahrén, B. (2007) G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes. Pharmacol. Ther. 116, 437-448
-
(2007)
Pharmacol. Ther.
, vol.116
, pp. 437-448
-
-
Winzell, M.S.1
Ahrén, B.2
-
37
-
-
0024468572
-
Muscarinic stimulation and antagonism and glucoregulation in nondiabetic and obese hyperglycemic mice
-
Fukudo, S., Virnelli, S., Kuhn, C. M., Cochrane, C., Feinglos, M. N., and Surwit, R. S. (1989) Muscarinic stimulation and antagonism and glucoregulation in nondiabetic and obese hyperglycemic mice. Diabetes 38, 1433-1438
-
(1989)
Diabetes
, vol.38
, pp. 1433-1438
-
-
Fukudo, S.1
Virnelli, S.2
Kuhn, C.M.3
Cochrane, C.4
Feinglos, M.N.5
Surwit, R.S.6
-
38
-
-
70449699592
-
Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents
-
Arakawa, M., Ebato, C., Mita, T., Hirose, T., Kawamori, R., Fujitani, Y., and Watada, H. (2009) Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents. Biochem. Biophys. Res. Commun. 390, 809-814
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 809-814
-
-
Arakawa, M.1
Ebato, C.2
Mita, T.3
Hirose, T.4
Kawamori, R.5
Fujitani, Y.6
Watada, H.7
-
39
-
-
33847617011
-
Mechanisms of action of glucagon-like peptide 1 in the pancreas
-
Doyle, M. E., and Egan, J. M. (2007) Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacol. Ther. 113, 546-593
-
(2007)
Pharmacol. Ther.
, vol.113
, pp. 546-593
-
-
Doyle, M.E.1
Egan, J.M.2
-
40
-
-
34548362105
-
Muscarinic acetylcholine receptors: Mutant mice provide new insights for drug development
-
Wess, J., Eglen, R. M., and Gautam, D. (2007) Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development. Nat. Rev. Drug Discov. 6, 721-733
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 721-733
-
-
Wess, J.1
Eglen, R.M.2
Gautam, D.3
-
41
-
-
0036733358
-
Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling
-
Hollinger, S., and Hepler, J. R. (2002) Cellular regulation of RGS proteins: modulators and integrators of G protein signaling. Pharmacol. Rev. 54, 527-559
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 527-559
-
-
Hollinger, S.1
Hepler, J.R.2
-
42
-
-
0033783132
-
GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins
-
Ross, E. M., and Wilkie, T. M. (2000) GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Annu. Rev. Biochem. 69, 795-827
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 795-827
-
-
Ross, E.M.1
Wilkie, T.M.2
|