Knockout of spinophilin, an endogenous antagonist of arrestin-dependent α2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences

Behavioural Brain Research

Volumn 197, Issue 2, 2009, Pages 457-461

  Nag, Subodh ^a   Wang, Qin ^b   Limbird, Lee E ^a   Mokha, Sukhbir S ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

2 Adrenoceptors; Analgesia; Clonidine; Pain; Sex differences; Spinophilin

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; ESTROGEN; RETINA S ANTIGEN; SPINOPHILIN; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DIESTRUS; DRUG EFFECT; ENDOCYTOSIS; FEMALE; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PAIN; PRIORITY JOURNAL; PROESTRUS; SEDATION; SEX DIFFERENCE; TAIL FLICK TEST; WILD TYPE;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ARRESTIN; CLONIDINE; ESTROGENS; FEMALE; HOT TEMPERATURE; MALE; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; REACTION TIME; RECEPTORS, ADRENERGIC, ALPHA-2; SEX FACTORS;

EID: 58149350017     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2008.09.036     Document Type: Article

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