Epigenetic imprinting by commensal probiotics inhibits the IL-23/IL-17 axis in an in vitro model of the intestinal mucosal immune system

Journal of Leukocyte Biology

Volumn 92, Issue 4, 2012, Pages 895-911

  Ghadimi, Darab ^a   Helwig, Ulf ^b   Schrezenmeir, Juergen ^a   Heller, Knut J ^a   de Vrese, Michael ^a  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

^b Partnership for Internal Medicine   (Germany)

Author keywords

Bacteria; Cytokines; Histone modification; Inflammation

Indexed keywords

CD40 ANTIGEN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 17; INTERLEUKIN 23; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; PROBIOTIC AGENT;

ANIMAL CELL; ARTICLE; BIFIDOBACTERIUM BREVE; CELL PROLIFERATION; CELL VIABILITY; COMMENSAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA METHYLATION; DRUG EFFECT; ENTERITIS; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIGENETICS; GENETIC TRANSFECTION; GENOME IMPRINTING; HISTONE ACETYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE CELL; INTESTINE MUCOSA; LACTOBACILLUS RHAMNOSUS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BIFIDOBACTERIUM; CELL PROLIFERATION; COCULTURE TECHNIQUES; DNA METHYLATION; EPIGENESIS, GENETIC; HISTONES; HT29 CELLS; HUMANS; IMMUNITY, MUCOSAL; INTERLEUKIN-17; INTERLEUKIN-23; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; NF-KAPPA B; PROBIOTICS;

BIFIDOBACTERIUM BREVE;

EID: 84868136017     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0611286     Document Type: Article

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