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Volumn 21, Issue 8, 2012, Pages 1697-1709

Intramyocardial injections of human mesenchymal stem cells following acute myocardial infarction modulate scar formation and improve left ventricular function

Author keywords

Animal model; Cell therapy; Echocardiography; Immunofluorescence; In situ hybridization; Mesenchymal stem cells (MSCs)

Indexed keywords

PLACEBO;

EID: 84868106220     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368911X627462     Document Type: Article
Times cited : (61)

References (38)
  • 3
    • 47149102903 scopus 로고    scopus 로고
    • Bone marrow derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature
    • Au, P.; Tam, J.; Fukumura, D.; Jain, R. K. Bone marrow derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood 111:4551-4558; 2008.
    • (2008) Blood , vol.111 , pp. 4551-4558
    • Au, P.1    Tam, J.2    Fukumura, D.3    Jain, R.K.4
  • 7
    • 14844304694 scopus 로고    scopus 로고
    • Isolation and transcription profiling of purified uncultured human stromal stem cells: Alteration of gene expression after in vitro cell culture
    • Boquest, A. C.; Shahdadfar, A.; Fronsdal, K.; Sigurjonsson, O.; Tunheim, S. H.; Collas, P.; Brinchmann, J. E. Isolation and transcription profiling of purified uncultured human stromal stem cells: Alteration of gene expression after in vitro cell culture. Mol. Biol. Cell 16:1131-1141; 2005.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 1131-1141
    • Boquest, A.C.1    Shahdadfar, A.2    Fronsdal, K.3    Sigurjonsson, O.4    Tunheim, S.H.5    Collas, P.6    Brinchmann, J.E.7
  • 9
    • 22144475112 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Shortand Long-term Effects
    • Dai, W.; Hale, S. L.; Martin, B. J.; Kuang, J. Q.; Dow, J. S.; Wold, L. E.; Kloner, R. A. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Shortand long-term effects. Circulation 112:214-223; 2005.
    • (2005) Circulation , vol.112 , pp. 214-223
    • Dai, W.1    Hale, S.L.2    Martin, B.J.3    Kuang, J.Q.4    Dow, J.S.5    Wold, L.E.6    Kloner, R.A.7
  • 10
    • 0014148162 scopus 로고
    • Clonal analysis of determination dynamics in cultures of imaginal disks in Drosophila melanogaster
    • Gehring, W. Clonal analysis of determination dynamics in cultures of imaginal disks in Drosophila melanogaster. Dev. Biol. 16:438-456; 1967.
    • (1967) Dev. Biol , vol.16 , pp. 438-456
    • Gehring, W.1
  • 11
    • 65649128494 scopus 로고    scopus 로고
    • Early beneficial effects of bone marrowderived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction
    • Gnecchi, M.; He, H.; Melo, L. G.; Noiseaux, N.; Morello, F.; De Boer, R. A.; Zhang, L.; Pratt, R. E.; Dzau, V. J.; Ingwall, J. S. Early beneficial effects of bone marrowderived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction. Stem Cells 27:971-979; 2009.
    • (2009) Stem Cells , vol.27 , pp. 971-979
    • Gnecchi, M.1    He, H.2    Melo, L.G.3    Noiseaux, N.4    Morello, F.5    de Boer, R.A.6    Zhang, L.7    Pratt, R.E.8    Dzau, V.J.9    Ingwall, J.S.10
  • 14
    • 0013914081 scopus 로고
    • Constancy, variation and type of determination and differentiation in cells from male genitalia rudiments of Drosophila melanogaster in permanent culture in vivo
    • Hadorn, E. Constancy, variation and type of determination and differentiation in cells from male genitalia rudiments of Drosophila melanogaster in permanent culture in vivo. Dev. Biol. 13:424-509; 1966.
    • (1966) Dev. Biol , vol.13 , pp. 424-509
    • Hadorn, E.1
  • 16
    • 77956885799 scopus 로고    scopus 로고
    • Chondrogenesis in a hyaluronic acid scaffold: Comparison between chondrocytes and MSC from bone marrow and adipose tissue
    • Jakobsen, R. B.; Shahdadfar, A.; Reinholt, F. P.; Brinchmann, J. E. Chondrogenesis in a hyaluronic acid scaffold: Comparison between chondrocytes and MSC from bone marrow and adipose tissue. Knee Surg. Sports Traumatol. Arthrosc. 18:1407-1416; 2009.
    • (2009) Knee Surg. Sports Traumatol. Arthrosc , vol.18 , pp. 1407-1416
    • Jakobsen, R.B.1    Shahdadfar, A.2    Reinholt, F.P.3    Brinchmann, J.E.4
  • 17
    • 67649171661 scopus 로고    scopus 로고
    • Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6
    • Lee, R. H.; Pulin, A. A.; Seo, M. J.; Kota, D. J.; Ylostalo, J.; Larson, B. L.; Semprun-Prieto, L.; Delafontaine, P.; Prockop, D. J. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6. Cell Stem Cell 5:54-63; 2009.
    • (2009) Cell Stem Cell , vol.5 , pp. 54-63
    • Lee, R.H.1    Pulin, A.A.2    Seo, M.J.3    Kota, D.J.4    Ylostalo, J.5    Larson, B.L.6    Semprun-Prieto, L.7    Delafontaine, P.8    Prockop, D.J.9
  • 24
    • 30944432553 scopus 로고    scopus 로고
    • Cell-based cardiac repair: Reflections at the 10-year point
    • Murry, C. E.; Field, L. J.; Menasche, P. Cell-based cardiac repair: Reflections at the 10-year point. Circulation 112:3174-3183; 2005.
    • (2005) Circulation , vol.112 , pp. 3174-3183
    • Murry, C.E.1    Field, L.J.2    Menasche, P.3
  • 25
    • 33751038565 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation
    • Noiseux, N.; Gnecchi, M.; Lopez-Ilasaca, M.; Zhang, L.; Solomon, S. D.; Deb, A.; Dzau, V. J.; Pratt, R. E. Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation. Mol. Ther. 14:840-850; 2006.
    • (2006) Mol. Ther , vol.14 , pp. 840-850
    • Noiseux, N.1    Gnecchi, M.2    Lopez-Ilasaca, M.3    Zhang, L.4    Solomon, S.D.5    Deb, A.6    Dzau, V.J.7    Pratt, R.E.8
  • 29
    • 84961058932 scopus 로고
    • Simple techniques for the surgical occlusion of coronary vessels in the rat
    • Selye, H.; Bajusz, E.; Grasso, S.; Mendell, P. Simple techniques for the surgical occlusion of coronary vessels in the rat. Angiology 11:398-407; 1960.
    • (1960) Angiology , vol.11 , pp. 398-407
    • Selye, H.1    Bajusz, E.2    Grasso, S.3    Mendell, P.4
  • 31
    • 69849084725 scopus 로고    scopus 로고
    • Mesenchymal stem cells over- expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats
    • Tang, J.; Wang, J.; Yang, J.; Kong, X.; Zheng, F.; Guo, L.; Zhang, L.; Huang, Y. Mesenchymal stem cells over- expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats. Eur. J. Cardiothorac. Surg. 36:644-650; 2009.
    • (2009) Eur. J. Cardiothorac. Surg , vol.36 , pp. 644-650
    • Tang, J.1    Wang, J.2    Yang, J.3    Kong, X.4    Zheng, F.5    Guo, L.6    Zhang, L.7    Huang, Y.8
  • 32
    • 34547647436 scopus 로고    scopus 로고
    • PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling
    • Thomas, P. E.; Peters-Golden, M.; White, E. S.; Thannickal, V. J.; Moore, B. B. PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling. Am. J. Physiol. Lung Cell. Mol. Physiol. 293:L417-L428; 2007.
    • (2007) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.293
    • Thomas, P.E.1    Peters-Golden, M.2    White, E.S.3    Thannickal, V.J.4    Moore, B.B.5
  • 33
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma, C.; Pittenger, M. F.; Cahill, K. S.; Byrne, B. J.; Kessler, P. D. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105:93-98; 2002.
    • (2002) Circulation , vol.105 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3    Byrne, B.J.4    Kessler, P.D.5
  • 36
    • 58149170640 scopus 로고    scopus 로고
    • Biodistribution, long-term survival, and safety of human adipose tissuederived mesenchymal stem cells transplanted in nude mice by high sensitivity non-invasive bioluminescence imaging
    • Vilalta, M.; Degano, I. R.; Bago, J.; Gould, D.; Santos, M.; Garcia-Arranz, M.; Ayats, R.; Fuster, C.; Chernajovsky, Y.; Garcia-Olmo, D.; Rubio, N.; Blanco, J. Biodistribution, long-term survival, and safety of human adipose tissuederived mesenchymal stem cells transplanted in nude mice by high sensitivity non-invasive bioluminescence imaging. Stem Cells Dev. 17:993-1003; 2008.
    • (2008) Stem Cells Dev , vol.17 , pp. 993-1003
    • Vilalta, M.1    Degano, I.R.2    Bago, J.3    Gould, D.4    Santos, M.5    Garcia-Arranz, M.6    Ayats, R.7    Fuster, C.8    Chernajovsky, Y.9    Garcia-Olmo, D.10    Rubio, N.11    Blanco, J.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.