Polycystin-1 regulates amphiregulin expression through CREB and AP1 signalling: Implications in ADPKD cell proliferation

Journal of Molecular Medicine

Volumn 90, Issue 11, 2012, Pages 1267-1282

  Aguiari, Gianluca ^a   Bizzarri, Fabiana ^a   Bonon, Anna ^a   Mangolini, Alessandra ^a   Magri, Eros ^a   Pedriali, Massimo ^a   Querzoli, Patrizia ^a   Somlo, Stefan ^b   Harris, Peter C ^c   Catizone, Luigi ^d   Del Senno, Laura ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Mayo Clinic   (United States)

^d S ANNA HOSPITAL   (Italy)

Author keywords

ADPKD; Amphiregulin; AP1; cAMP; Cell proliferation; CREB

Indexed keywords

AMPHIREGULIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; POLYCYSTIN 1; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CELL; KIDNEY PARENCHYMA; KIDNEY POLYCYSTIC DISEASE; MICROARRAY ANALYSIS; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; CELL PROLIFERATION; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE SILENCING; GLYCOPROTEINS; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MUTAGENESIS; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRPP CATION CHANNELS;

EID: 84868096068     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-012-0902-3     Document Type: Article

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