A plethora of epidermal growth factor-like proteins in polycystic kidneys

Kidney International

Volumn 65, Issue 6, 2004, Pages 2441-2442

  Wilson, Patricia D ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Amphiregulin; Epidermal growth factor (EGF); Heparin binding EGF; Polycystic kidney disease; Receptors; Transforming growth factor alpha

Indexed keywords

EPIDERMAL GROWTH FACTOR;

EDITORIAL; GENE MUTATION; HUMAN; KIDNEY DEVELOPMENT; KIDNEY POLYCYSTIC DISEASE; MITOGENESIS; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 2442682710     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.00667.x     Document Type: Editorial

References (13)

1. DU J, WILSON PD: Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD. Am J Physiol 269:C487-495, 1995
2. WILSON PD, FALKENSTEIN D: The pathology of human renal cystic disease. Curr Top Pathol 88:1-50, 1995
3. ORELLANA SA, SWEENEY WE, NEFF CD, AVNER ED: Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int 47:490-499, 1995
4. LIN F, HIESBERGER T, CORDES K, et al: Kidney-speciflc inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease. Proc Natl Acad Sci USA 100:5286-5291, 2003
5. RICHARDS WG, SWEENEY WE, YODER BK, et al: Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease. J Clin Invest 101:935-939, 1998
6. SWEENEY WE, CHEN Y, NAKANISHI K, et al: Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int 57:33-40, 2000
7. WILSON PD, DU J, NORMAN JT: Autocrine, endocrine and paracrine regulation of growth abnormalities in autosomal dominant polycystic kidney disease. Eur J Cell Biol 61:131-138, 1993
8. SWEENEY WE, JR., AVNER ED: Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. Am J Physiol 275:F387-394, 1998
9. GOODYER PR, MULLIGAN L, GOODYER CG: Expression of growth-related genes in human fetal kidney. Am J Kidney Dis 17:608-610, 1991
10. LOWDEN DA, LINDEMANN GW, MERLINO G, et al: Renal cysts in transgenic mice expressing transforming growth factor-alpha. J Lab Clin Med 124:386-394, 1994
11. MACRAE DELL K, NEMO R, SWEENEY WE JR., AVNER ED: EGF-related growth factors in the pathogenesis of murine ARPKD. Kidney Int 65:2018-2029, 2004
12. SCHAFER B, GSCHWIND A, ULLRICH A: Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion. Oncogene 23:991-999, 2004
13. TAKEMURA T, HINO S, OKADA M, et al: Role of membrane-bound heparin-binding epidermal growth factor-like growth factor (HB-EGF) in renal epithelial cell branching Kidney Int 61:1968-1979, 2002