Mutation in Elongation Factor G Confers Resistance to the Antibiotic Argyrin in the Opportunistic Pathogen Pseudomonas aeruginosa

ChemBioChem

Volumn 13, Issue 16, 2012, Pages 2339-2345

  Bielecki, Piotr ^a,b   Lukat, Peer ^a,c   Hüsecken, Kristina ^c   Dötsch, Andreas ^a,b   Steinmetz, Heinrich ^a   Hartmann, Rolf W ^c   Müller, Rolf ^a,c   Häussler, Susanne ^a,b  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Antibiotics; Natural products; Resistance; Target identification; Whole genome sequencing

Indexed keywords

ANTIBIOTIC AGENT; ARGYRIN; ELONGATION FACTOR G; FUSIDIC ACID; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENOME; GENE SEQUENCE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PSEUDOMONAS AERUGINOSA; SURFACE PLASMON RESONANCE;

ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MUTATION; PEPTIDE ELONGATION FACTOR G; PEPTIDES, CYCLIC; PSEUDOMONAS AERUGINOSA; STRUCTURE-ACTIVITY RELATIONSHIP;

PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS;

EID: 84868095997     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201200479     Document Type: Article

References (31)

1. M. A. Fischbach, C. T. Walsh, Science 2009, 325, 1089-1093.
2. H. W. Boucher, G. H. Talbot, J. S. Bradley, J. E. Edwards, D. Gilbert, L. B. Rice, M. Scheld, B. Spellberg, J. Bartlett, Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2009, 48, 1-12.
3. P. Grossi, D. Dalla Gasperina, Expert Rev. Anti-Infect. Ther. 2006, 4, 639-662.
4. P. D. Lister, D. J. Wolter, N. D. Hanson, Clin. Microbiol. Rev. 2009, 22, 582-610.
5. S. Amini, S. Tavazoie, Curr. Opin. Microbiol. 2011, 14, 513-518.
6. S. Garbom, A. Forsberg, H. Wolf-Watz, B. M. Kihlberg, Infect. Immun. 2004, 72, 1333-1340;
7. A. E. Clatworthy, E. Pierson, D. T. Hung, Nat. Chem. Biol. 2007, 3, 541-548;
8. S. V. Lynch, J. P. Wiener-Kronish, Curr. Opin. Critical Care 2008, 14, 593-599.
9. J. Feng, A. Lupien, H. Gingras, J. Wasserscheid, K. Dewar, D. Legare, M. Ouellette, Genome Res. 2009, 19, 1214-1223;
10. T. J. Albert, D. Dailidiene, G. Dailide, J. E. Norton, A. Kalia, T. A. Richmond, M. Molla, J. Singh, R. D. Green, D. E. Berg, Nat. Methods 2005, 2, 951-953;
11. T. Downing, H. Imamura, S. Decuypere, T. G. Clark, G. H. Coombs, J. A. Cotton, J. D. Hilley, S. de Doncker, I. Maes, J. C. Mottram, M. A. Quail, S. Rijal, M. Sanders, G. Schonian, O. Stark, S. Sundar, M. Vanaerschot, C. Hertz-Fowler, J. C. Dujardin, M. Berriman, Genome Res. 2011, 21, 2143-2156;
12. M. M. Mwangi, S. W. Wu, Y. Zhou, K. Sieradzki, H. de Lencastre, P. Richardson, D. Bruce, E. Rubin, E. Myers, E. D. Siggia, A. Tomasz, Proc. Natl. Acad. Sci. USA 2007, 104, 9451-9456.
13. R. E. Hancock, D. P. Speert, Drug Resist. Updates 2000, 3, 247-255.
14. Z. Feng, D. Chakraborty, S. B. Dewell, B. V. Reddy, S. F. Brady, J. Am. Chem. Soc. 2012, 134, 2981-2987.
15. F. Sasse, H. Steinmetz, T. Schupp, F. Petersen, K. Memmert, H. Hofmann, C. Heusser, V. Brinkmann, P. von Matt, G. Hofle, H. Reichenbach, J. Antibiot. 2002, 55, 543-551.
16. Y. G. Gao, M. Selmer, C. M. Dunham, A. Weixlbaumer, A. C. Kelley, V. Ramakrishnan, Science 2009, 326, 694-699.
17. T. Norstrom, J. Lannergard, D. Hughes, Antimicrob. Agents Chemother. 2007, 51, 4438-4446;
18. A. A. Dahlfors, C. G. Kurland, J. Mol. Biol. 1990, 216, 311-314;
19. I. Nagaev, J. Bjorkman, D. I. Andersson, D. Hughes, Mol. Microbiol. 2001, 40, 433-439;
20. U. Johanson, D. Hughes, Gene 1994, 143, 55-59.
21. B. Stauch, B. Simon, T. Basile, G. Schneider, N. P. Malek, M. Kalesse, T. Carlomagno, Angew. Chem. 2010, 122, 4026-4030; Angew. Chem. Int. Ed. 2010, 49, 3934-3938.
22. M. A. Larkin, G. Blackshields, N. P. Brown, R. Chenna, P. A. McGettigan, H. McWilliam, F. Valentin, I. M. Wallace, A. Wilm, R. Lopez, J. D. Thompson, T. J. Gibson, D. G. Higgins, Bioinformatics 2007, 23, 2947-2948.
23. L. A. Kelley, M. J. Sternberg, Nat. Protoc. 2009, 4, 363-371.
24. H. Li, J. Ruan, R. Durbin, Genome Res. 2008, 18, 1851-1858.
25. K. E. Holt, Y. Y. Teo, H. Li, S. Nair, G. Dougan, J. Wain, J. Parkhill, Bioinformatics 2009, 25, 2074-2075.
26. T. T. Hoang, R. R. Karkhoff-Schweizer, A. J. Kutchma, H. P. Schweizer, Gene 1998, 212, 77-86.
27. C. W. Saltikov, D. K. Newman, Proc. Natl. Acad. Sci. USA 2003, 100, 10983-10988.
28. S. E. West, H. P. Schweizer, C. Dall, A. K. Sample, L. J. Runyen-Janecky, Gene 1994, 148, 81-86.
29. F. W. Studier, Protein Expression Purif. 2005, 41, 207-234.
30. E. Gasteiger, A. Gattiker, C. Hoogland, I. Ivanyi, R. D. Appel, A. Bairoch, Nucleic Acids Res. 2003, 31, 3784-3788.
31. Y. Chen, R. K. Koripella, S. Sanyal, M. Selmer, FEBS J. 2010, 277, 3789-3803.