At low precursor frequencies, the T-cell response to chronic self-antigen results in anergy without deletion

European Journal of Immunology

Volumn 42, Issue 11, 2012, Pages 2875-2880

  Steinert, Elizabeth M ^a   Schwartz, Ronald H ^b   Singh, Nevil J ^b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Clonal anergy; Clonal deletion; Immunological tolerance; Precursor frequency; T cells

Indexed keywords

AUTOANTIGEN; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL EXPANSION; CELL FATE; CELL FUNCTION; CELL STIMULATION; CELLULAR IMMUNITY; CLONAL ANERGY; CONTROLLED STUDY; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE COUNT; MOUSE; NONHUMAN; PRE T LYMPHOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; AUTOANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CLONAL ANERGY; FLOW CYTOMETRY; IMMUNE TOLERANCE; INTERLEUKIN-2; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 84868092582     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201242518     Document Type: Article

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