β-catenin and K-ras mutations and RASSF1A promoter methylation in Taiwanese colorectal cancer patients

Genetic Testing and Molecular Biomarkers

Volumn 16, Issue 11, 2012, Pages 1277-1281

  Chen, Shee Ping ^a   Wu, Chang Chieh ^b   Huang, Sung Ying ^c   Kang, Jung Cheng ^d   Chiu, Sheng Chun ^a   Yang, Kuo Liang ^a   Pang, Cheng Yoong ^a,e  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

^d TAIWAN ADVENTIST HOSPITAL   (Taiwan)

^e TZU CHI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; FLUOROURACIL; K RAS PROTEIN;

AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER RADIOTHERAPY; COLORECTAL CANCER; DNA METHYLATION; EXON; FEMALE; GENE DELETION; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; MAJOR CLINICAL STUDY; MALE; METHYLATION; MISSENSE MUTATION; NONSENSE MUTATION; PROMOTER REGION; TAIWAN;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BETA CATENIN; COLORECTAL NEOPLASMS; DNA METHYLATION; FEMALE; GENES, RAS; HUMANS; MALE; MIDDLE AGED; MUTATION; PROMOTER REGIONS, GENETIC; TAIWAN; TUMOR SUPPRESSOR PROTEINS;

EID: 84868027431     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2012.0126     Document Type: Article

References (25)

1. Behrens J. (2005) The role of the Wnt signalling pathway in colorectal tumorigenesis. Biochem Soc Trans 33:672-675. (Pubitemid 41160836)
2. Belinsky SA, Palmisano WA, Gilliland FD, et al. (2002) Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Res 62:2370-2377. (Pubitemid 34411720)
3. Bläker H, Hofmann WJ, Rieker RJ, et al. (1999) Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma. Genes Chromosomes Cancer 25:399-402. (Pubitemid 29326149)
4. Chen SP, Chiu SC, Wu CC, et al. (2009a) The association of methylation in the promoter of APC and MGMT and the prognosis of Taiwanese CRC patients. Genet Test Mol Biomarkers 13:67-71.
5. Chen SP, Tsai ST, Jao SW, et al. (2006) Single nucleotide polymorphisms of the APC gene and colorectal cancer risk: a casecontrol study in Taiwan. BMC Cancer 6:83.
6. Chen SP, Wu CC, Lin SZ, et al. (2009b) Prognostic significance of interaction between somatic APC mutations and 5-fluorouracil adjuvant chemotherapy in Taiwanese colorectal cancer subjects. Am J Clin Oncol 32:122-126.
7. Department of Health Executive Yuan, R.O.C. (2012) Available at www.doh.gov.tw/EN2006/index-EN.aspx (accessed June 11 2012).
8. de Vogel S,WeijenbergMP, Herman JG, et al. (2009) M.MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events. Ann Oncol 20:1216-1222.
9. Esteller M, Toyota M, Sanchez-Cespedes M, et al. (2000) Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res 60:2368-2371. (Pubitemid 30262424)
10. Fearon ER, Vogelstein B. (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767.
11. Feinberg AP, Gehrke CW, Kuo KC, et al. (1988) Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res 48:1159-1161. (Pubitemid 18075525)
12. Greenspan EJ, Jablonski MA, Rajan TV, et al. (2006) Epigenetic alterations in RASSF1A in human aberrant crypt foci. Carcinogenesis 27:1316-1322. (Pubitemid 43985406)
13. Ilyas M, Tomlinson IP, Rowan A, et al. (1997) Beta-catenin mutations in cell lines established from human colorectal cancers. Proc Natl Acad Sci USA 94:10330-10334. (Pubitemid 27407041)
14. Kelley RK, Wang G, Venook AP. (2011) Biomarker use in colorectal cancer therapy. J Natl Compr Canc Netw 9:1293-1302.
15. Koch A, Denkhaus D, Albrecht S, et al. (1999) Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res 59:269-273. (Pubitemid 29048850)
16. Lamlum H, Papadopoulou A, Ilyas M, et al. (2000) APC mutations are sufficient for the growth of early colorectal adenomas. Proc Natl Acad Sci USA 97:2225-2228. (Pubitemid 30134050)
17. Lee S, Hwang KS, Lee HJ, et al. (2004) Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia. Lab Invest 84:884-893. (Pubitemid 38833248)
18. Legoix P, Bluteau O, Bayer J, et al. (1999) Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity. Oncogene 18:4044-4046. (Pubitemid 29361344)
19. Morin PJ, Sparks AB, Korinek V, et al. (1997) Activation of betacatenin-Tcf signaling in colon cancer by mutations in betacatenin or APC. Science 275:1787-1790. (Pubitemid 27136715)
20. Online Mendelian Inheritance in Man (2012) CATENIN, BETA-1; CTNNB1. Available at omim.org/entry/116806?search= Beta-Catenin&highlight = betacatenin (accessed June 11 2012).
21. Segditsas S, Tomlinson I. (2006) Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 25:7531-7537. (Pubitemid 44885752)
22. van Engeland M, Roemen GM, Brink M, et al. (2002) K-ras mutations and RASSF1A promoter methylation in colorectal cancer. Oncogene 21:3792-3795. (Pubitemid 34620542)
23. van Engeland M, Weijenberg MP, Roemen GM, et al. (2003) Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer. Cancer Res 63:3133-3137. (Pubitemid 36735864)
24. Wagner KJ, Cooper WN, Grundy RG, et al. (2002) Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer. Oncogene 21:7277-7282. (Pubitemid 35305616)
25. Weitz J, Koch M, Debus J, et al. (2005) Colorectal cancer. Lancet 365:153-165. (Pubitemid 40091806)