β-catenin accumulation and mutation of the CTNNBI gene in hepatoblastoma

Genes Chromosomes and Cancer

Volumn 25, Issue 4, 1999, Pages 399-402

  Bläker, Hendrik ^a   Hofmann, Walter J ^a   Rieker, Ralf J ^a   Penzel, Roland ^a   Graf, Matthias ^a   Otto, Herwart F ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN;

ARTICLE; GENE EXPRESSION; GENE INACTIVATION; GENE MUTATION; GENE SEQUENCE; HEPATOBLASTOMA; HUMAN; IMMUNOHISTOCHEMISTRY; PATHOGENESIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

BETA CATENIN; CADHERINS; CYTOSKELETAL PROTEINS; GENES, APC; HEPATOBLASTOMA; HUMANS; LIVER NEOPLASMS; MUTATION; TRANS-ACTIVATORS;

EID: 0345643474     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199908)25:4<399::AID-GCC14>3.3.CO;2-O     Document Type: Article

References (19)

1. Albrecht S, von Schweinitz D, Waha A, Kraus JA, von Deimling A, Pietsch T. 1994. Loss of maternal alleles on chromosome 11p in hepatoblastoma. Cancer Res 54:5041-5044.
2. Alman BA, Li C, Pajerski ME, Diaz-Cano S, Wolfe HJ. 1997. Increased β-catenin protein and somatic APC mutations in sporadic aggressive fibromatosis (desmoid tumors). Am J Pathol 151:329-334.
3. Byrne JA, Simms LA, Little MH, Algar EM, Smith PJ. 1993. Three non-overlapping regions of chromosome 11p allele loss identified in infantile tumors of adrenal and liver. Genes Chromosomes Cancer 8:104-111.
4. Cooper PR, Smilinich NJ, Day CD, Nowak NJ, Reid HL, Pearsall RS, Recce M, Prawitt D, Landers J, Housman DE, Winterpacht A, Zabel BU, Pelletier J, Weissman BE, Shows TB, Higgins MJ. 1998. Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain. Genomics 49:38-51.
5. DeBaun MR, Tucker MA. 1998. Risk of cancer during the first years of life in children from the Beckwith-Wiedemann Syndrome Registry. J Pediatr 132:398-400.
6. Gumbiner BM. 1995. Signal transduction by β-catenin. Curr Opin Cell Biol 7:634-640.
7. Hughes LJ, Michels VV. 1992. Risk of hepatoblastoma in familial adenomatous polyposis. Am J Med Genet 43:1023-1025.
8. Kitaeva MN, Grogan L, Wiliams JP, Dimond E, Nakahara K, Hauisner P, DeNobile JW, Soballe PW, Kirsch IR. 1997. Mutations of the β-catenin gene are uncommon in colorectal cancer occuring in occasional replication error-positive tumors. Cancer Res 57:4478-4481.
9. -/- colon carcinoma. Science 275:1784-1787.
10. Kurahashi H, Takami K, Oue T, Kusafuku T, Okada A, Tawa A, Okada S, Nishisho I. 1995. Biallelic inactivation of the APC gene in hepatoblastoma. Cancer Res 55:5007-5011.
11. Li C, Bapat B, Alman BA. 1998. Adenomatous polyposis coli gene mutation alters proliferation through its β-catenin-regulatory function in aggressive fibromatosis (desmoid tumor). Am J Pathol 153:709-714.
12. Miyoshi Y, Iwao K, Nagasawa Y, Aihara T, Sasaki Y, Imaoka S, Murata M, Shimano T, Nakamira Y. 1998. Activation of the β-catenin gene in hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res 58:2524-2527.
13. Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. 1997. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC. Science 275:1787-1790.
14. Munemitsu S, Albert I, Souza B, Rubinfeld B, Plakis P. 1995. Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Nat Acad Sci USA 92:3046-3050.
15. Oda H, Imai Y, Nakatsuru Y, Hata J, Ishikawa T. 1996. Somatic mutation of the APC gene in sporadic hepatoblastoma. Cancer Res 56:3320-3323.
16. Palacios J, Gamallo C. 1998. Mutations in the β-catenin gene (CTNNB1) in endometroid ovarian carcinomas. Cancer Res 58: 1344-1347.
17. Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P. 1996. Binding of GSK-3β to the APC-β-catenin complex and regulation of complex assembly. Science 272:1023-1026.
18. Rubinfeld B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P. 1997 Stabilization of β-catenin by genetic defects in melanoma cell lines. Science 275:1790-1792.
19. Schwienbacher C, Sabbioni S, Campi M, Veeronese A, Bernardi G, Menegatti A, Hatada I, Mukai T, Ohashi H, Barbanti-Brodano G, Croce CM, Negrini M. 1998. Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples. Proc Nat Acad Sci USA 95:3873-3878.