Chemotherapy Drugs Form Ion Pores in Membranes Due to Physical Interactions with Lipids

Chemical Biology and Drug Design

Volumn 80, Issue 6, 2012, Pages 992-1002

  Ashrafuzzaman, Mohammad ^a,b   Tseng, Chih Yuan ^b   Duszyk, Marek ^b   Tuszynski, Jack A ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Chemotherapy drugs; Electrophysiology; Electrostatic interaction; Ion pore; Lipid bilayer membrane; Molecular dynamics simulation; Van der Waals interaction

Indexed keywords

LIPID; PACLITAXEL; THIOCOLCHICOSIDE;

ARTICLE; CELL MEMBRANE PERMEABILITY; COMPUTER MODEL; CYTOTOXICITY; DRUG PENETRATION; ELECTROPHYSIOLOGY; LIPID MEMBRANE; MEMBRANE CONDUCTANCE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; POROSITY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; CELL MEMBRANE; COLCHICINE; HUMANS; IONS; LIPID BILAYERS; MOLECULAR DYNAMICS SIMULATION; PACLITAXEL; PEPTIDES; STATIC ELECTRICITY;

EID: 84868015417     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12060     Document Type: Article

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