Chemotherapy drugs thiocolchicoside and taxol permeabilize lipid bilayer membranes by forming ion pores

Journal of Physics: Conference Series

Volumn 329, Issue 1, 2011, Pages

  Ashrafuzzaman, Md ^a   Duszyk, M ^a   Tuszynski, J A ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; BIOELECTRIC POTENTIALS; CELL DEATH; CELLS; CHEMOTHERAPY; CYTOLOGY; CYTOTOXICITY; DISEASES; ELECTRODYNAMICS; ELECTROPHYSIOLOGY; ELECTROSTATICS; IONS; LIPIDS; MOLECULES; PHOSPHOLIPIDS;

ELECTROPHYSIOLOGICAL RECORDINGS; ENERGETIC COUPLING; LIPID BILAYER MEMBRANES; PHOSPHOLIPID BILAYER MEMBRANES; SCREENED COULOMB INTERACTION; TIME-DEPENDENT CHANGES; TRANSMEMBRANE POTENTIALS; TRIANGULAR SHAPES;

LIPID BILAYERS;

EID: 84859551495     PISSN: 17426588     EISSN: 17426596     Source Type: Conference Proceeding    
DOI: 10.1088/1742-6596/329/1/012029     Document Type: Conference Paper

References (69)

1. Seidemann P, Fjellner B, Johannesson A 1987 Psoriatic arthritis treated with oral colchicine J. Rheumatol 14 777-779 (Pubitemid 17137496)
2. Callen JP 1985 Colchicine is effective in controlling chronic cutaneous vasculitis in lupus erythematosus J. Am. Acad. Dermatol. 13 193-200 (Pubitemid 15007110)
3. Rosenman SJ, Ganji AA, Gallatin WM 1991 contact dependent redistribution of cell surface adhesion and activation molecules reorganization FASEB J. 5 1603
4. Mekory YA, Baram D, Goldberg A, Klajman A 1989 Inhibition of delayed hypersensitivity in mice by colchicines: Mechanism of inhibition of contact sensibility in vivo Cell. Immunol. 120 330-340 (Pubitemid 19142789)
5. Borisy GO, Taylor EW 1967 The mechanism of action of colchicine: Colchicine binding to seaurchin eggs and the mitotic apparatus J. Cell. Biol. 34 533-548
6. Matsumoto G, Sakai H 1979 Microtubules inside the Plasma Membrane of Squid Giant Axons and their Possible Physiological Function J. Membrane Biol. 50 1-14 (Pubitemid 10189210)
7. Haga T, Kurokawa M 1975 Microtubule formation from two components separated by gel filtration of a tubulin preparation Biochim. Biophys. Acta 392 335
8. Agutter PS, Suckling KE 1982 Effect of colchicine on mammalian liver nuclear envelope and on nucleo-cytoplasmic RNA transport Biochim. Biophys. Acta 698 223-229 (Pubitemid 13198230)
9. Holmes FA, Kudelka AP, Kavanagh JJ, Huber MH, Ajani JA, Valero V 1995 Current Status of Clinical Trials with Paclitaxel and Docutaxel Taxane Anticancer Agents: Basic Science and Current Status (ACS Symposium Series No. 583) ed Georg, G I, Chen, T C, Ojima, I, Vyas, D M, Eds. (American Chemical Society: Washington, DC) p 31-57
10. Schiff PB, Fant J, Horwitz SB 1979 Promotion of Microtubule Assembly vitro by Taxol. Nature 277 665-666
11. Fisherman J, McCabe M, Hillig M 1992 Phase I study of taxol and doxorubucin (Dox) with G-CSF in previously untreated metastatic breast cancer Proc. Am.SOC. Clin. Oncol. 1175A
12. Sharma A, Straubinger, RM 1994 Novel taxol formulations: Preparation and characterization of taxol-containing liposomes Pharm. Res. 11 889-896 (Pubitemid 24210627)
13. Sonee M, Barron E, Yarber FA, Hamm-Alvarez SF 1998 Taxol inhibits endosomal-lysosomal membrane trafficking at two distinct steps in CV-1 cells Am. J. Physiol. Cell Physiol. 44 1630-1639
14. Balasubramanian SV, Straubinger RM 1994 Taxol-lipid interactions: taxol-dependent effects on the physical properties of model membranes Biochemistry 33 8941-8947 (Pubitemid 24258002)
15. Shiba M, Watanabe E, Sasakawa S, Ikeda Y 1988 Effects of taxol and colchicines on platelet membrane properties Thromb Res. 52 313-323 (Pubitemid 18261712)
16. Mons S, Veretout F, Carlier M, Erk I, Lepault J, Trudel E, Salesse C, Ducray P, Mioskowski C, Lebeau L 2000 The interaction between lipid derivatives of colchicines and tubulin: Consequences of the interaction of the alkaloid with lipid membranes Biochim. Biophys. Acta 1468 381-395
17. Weisenberg RC, Deery WJ, Dickinson PJ 1976 Tubulin-nucleotide interactions during the polymerization and depolymerization of microtubules Biochemistry 15 4248-4254
18. Wang HW, Nogales E 2005 Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly Nature 435 911-915 (Pubitemid 40896310)
19. Unger E, Bohm KJ, Vater W 1990 Structural diversity and dynamics of microtubules and polymorphic tubulin assemblies Electron Microsc Rev 3 355-395
20. Pichichero ME, Avers CJ 1973 The evolution of cellular movement in eukaryotes: the role of microfilaments and microtubules Subcell Biochem 2 97-105
21. Hyams JS, Stebbings H 1979 The mechanism of microtubule associated cytoplasmic transport. Isolation and preliminary characterisation of a microtubule transport system Cell Tissue Res 196 103-116 (Pubitemid 9213966)
22. Derry WB, Wilson L, Khan IA, Luduena RF, Jordan MA 1997 Taxol differentially modulates the dynamics of microtubules assembled from unfractionated and purified beta-tubulin isotypes Biochemistry 36 3554-3562 (Pubitemid 27143509)
23. Wani MC, Taylor HL, Wall ME, Coggon P, McPhail AT 1971 Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia J Am Chem Soc 93 2325-2327
24. Schiff PB, Horwitz SB 1980 Taxol stabilizes microtubules in mouse fibroblast cells Proc Natl Acad Sci U S A 77 1561-1565 (Pubitemid 10073801)
25. Ringel I, Horwitz SB 1991 Studies with RP 56976 (taxotere): a semisynthetic analogue of taxol J Natl Cancer Inst 83 288-291
26. Xiao H et al 2006 Insights into the mechanism of microtubule stabilization by Taxol Proc Natl Acad Sci U S A 103 10166-10173 (Pubitemid 44051138)
27. Ravelli RB et al 2004 Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain Nature 428 198-202 (Pubitemid 38374318)
28. Boheim G 1974 Statistical analysis of alamethicin channels in black lipid membranes J. Mem. Biol. 19 277-303
29. He K, Ludtke SJ, Huang HW, Worcester DL 1995 Antimicrobial peptide pores in membranes detected by neutron in-plane scattering Biochemistry 34 15614-15618
30. Andersen OS 1983 ION MOVEMENT THROUGH GRAMICIDIN A CHANNELS Studies on the Diffusion-controlled association step Biophys. J. 41 147-165 (Pubitemid 13124861)
31. Ashrafuzzaman M, Andersen OS 2007 Lipid bilayer elasticity and intrinsic curvature as regulators of channel function: a single molecule study Biophys. J. 421a
32. Ashrafuzzaman M, Andersen OS, McElhaney RN 2008 The antimicrobial peptide gramicidin S permeabilizes phospholipid bilayer membranes without forming discrete ion channels Biochim. Biophys. Acta 1778 2814-2822
33. Matsuzaki K, Murase O, Tokuda H, Fujii N, Miyajima K 1996 An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation Biochemistry 35 11361-11368 (Pubitemid 26299310)
34. Ludtke SJ, He K, Heller WT, Harroun TA, Yang L, Huang HW 1996 Membrane pores induced by magainin Biochemistry 35 13723-13728 (Pubitemid 26363914)
35. Yang L, Harroun T, Weiss TM, Ding L, Huang HW 2001 Barrel-stave model or toroidal model? A case study on melittin pores Biophys. J. 81 1475-1485 (Pubitemid 32783588)
36. Sobko AA, Kotova EA, Antonenko YN, Zakharov SD, Cramer WA 2006 Lipid dependence of the channel properties of a colicin E1-lipid toroidal pore The J. Biol. Chem. 281 14408-16 (Pubitemid 43848371)
37. Allende D, Simon SA, McIntosh TJ 2005 Melittin-induced bilayer leakage depends on lipid material properties: Evidence for toroidal pores Biophys J. 88 1828-1837 (Pubitemid 40976196)
38. Erdal H, Berndtsson M, Castro J, Brunk U, Shoshan MC, Linder S 2004 Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis Proc Natl Acad Sci USA 102 192-197 (Pubitemid 40094451)
39. Bechinger B 1997 Structure and functions of channel-forming peptides: magainins, sercopins, melittin and alamethicin J. Membr. Biol. 156 197-211 (Pubitemid 27208423)
40. Bechinger B 1999 The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy Biochim. Biophys. Acta 1462 157-183
41. Latorre M, Alvarez O 1981 Voltage-dependent channels in plannar lipid bilayer membranes Physiol. Rev. 61 77-150
42. Perozo E, Cortes DM, Sompornpisut P, Kloda A, Martinac B 2002 Open channel structure of MscL and the gating mechanism of mechanosensitive channels Nature 418 942-948 (Pubitemid 34976024)
43. Ashrafuzzaman M, Lampson MA, Greathouse DV, Koeppe II RE, Andersen OS 2006 Manipulating lipid bilayer material properties using biologically active amphipathic molecules J. Phys.: Condens. Matter 18 S1235-S1255
44. Gagliardi LJ 2005 Electrostatic Considerations in Mitogenesis Proceedings ESA Ann. Meeting 227-241
45. Ashrafuzzaman M, Tuszynski J 2011 Regulation of channel function due to coupling with a lipid bilayer J. Comput. Theor. Nanosci. in press (accepted)
46. Arseniev AS, Barsukov IL, Bystrov VF, Ovchinnikov YA 1986 Spatial structure of a gramicidin A transmembrane ion channel. NMR analysis in micelles Biol. Membr. 3 437-62
47. Ketchem RR, Roux B, Cross TA 1997 High-resolution polypeptide structure in a lamellar phase lipid environment from solid state NMR derived orientational constraints Structure 5 1655-69 (Pubitemid 28051978)
48. Townsley LE, Tucker WA, Sham S, Hinton JF 2001 Structures of gramicidins A, B, and C incorporated into sodium dodecyl sulfate micelles Biochemistry 40 11676-11686 (Pubitemid 32906030)
49. Wallace BA, Veatch WR, Blout ER 1981 Conformation of gramicidin A in phospholipid vesicles: circular dichroism studies of effects of ion binding, chemical modification, and lipid structure Biochemistry 20 5754-5760 (Pubitemid 12217506)
50. Allen TW, Andersen OS, Roux B 2004 Energetics of ion conduction through the gramicidin channel Proc. Natl. Acad. Sci. 101 117-122 (Pubitemid 38084213)
51. F de Meyer and B Smit 2009 Comment on "cluster formation of trans-membrane proteins due to hydrophobic mismatching" Phys. Rev. Lett. 102 219801
52. Huang HW 1986 Deformation free energy of bilayer membrane and its effect on gramicidin channel lifetime Biophys. J. 50 1061-1071
53. Helfrich P, Jakobsson E 1990 Calculation of deformation energies and conformations in lipid membranes containing gramicidin channels Biophys. J. 57 1075-1084 (Pubitemid 20134200)
54. Durkin JT, Providence LL, Koeppe II RE, Andersen OS 1993 Energetics of heterodimer formation among gramicidin analogues with an NH2-terminal addition or deletion consequences of missing a residue at the join in the channel J. Mol. Biol. 231 1102-1121 (Pubitemid 23209883)
55. Nielsen C, Goulian M, Andersen OS 1998 Energetics of inclusion-induced bilayer deformations Biophys. J. 74 1966-1983 (Pubitemid 28157932)
56. Nielsen C, Andersen OS 2000 Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature Biophys. J. 79 2583-2604
57. Lundbæk JA, Birn PHAJ, Sogaard R, Nielsen C, Girshman J, Bruno MJ, Tape SE, Egebjerg J, Greathouse DV, Mattice GL, Koeppe II RE, Andersen OS 2004 Regulation of sodium channel function by bilayer elasticity. The importance of hydrophobic coupling. Effects of micelle-forming amphiphiles and cholesterol J. Gen. Physiol. 123 599-621 (Pubitemid 38590861)
58. Lundbsek JA, Birn P, Tape SE, Toombes GE, Sogaard R, Koeppe II RE, Gruner SM, Hansen AJ, Andersen OS 2005 Capsaicin regulates voltage-dependent ssodium channels by altering lipid bilayer elasticity Mol. Pharmacol. 68 680-689 (Pubitemid 41206021)
59. Gruner SM 1985 Intrinsic curvature hypothesis for biomembrane lipid composition: A role for nonbilayer lipids Proc. Natl. Acad. Sci. USA 82 3665-3669
60. Andersen OS, Koeppe II RE 2007 Bilayer thickness and membrane protein function: an energetic perspective Annu. Rev. Biophys. Biomol. Struct. 36 107-130 (Pubitemid 46998112)
61. Ashrafuzzaman M, Beck H 2004 Vortex dynamics in two-dimensional Josephson junction arrays (University of Neuchatel) ch 5 p 85 http://doc.rero.ch/record/ 2894?lnfr
62. Harper PE, Mannock DA, Lewis RNAH, McElhaney RN, Gruner SM 2001 X-Ray diffraction structures of some phosphatidylethanolamine lamellar and inverted hexagonal phases Biophys. J. 81 2693-2706 (Pubitemid 33020056)
63. Parsegian A 1969 Energy of an Ion crossing a low dielectric membrane: solutions to four relevant electrostatic problems Nature 221 844-846
64. Grenbech-Jensen N, Mashl RJ, Bruinsma RF, Gelbart WM 1997 Counterion-induced attraction between rigid polyelectrolytes Phys. Rev. Lett. 78 2477-2480 (Pubitemid 127651906)
65. Goulian M, Mesquita ON, Fygenson DK, Nielsen C, Andersen OS 1998 Gramicidin channel kinetics under tension Biophys. J. 74 328-337 (Pubitemid 28041760)
66. Duan Y, Wu C, Chowdhury S, Lee MC, Xiong G, Zhang W, Yang R, Cieplak P, Luo R, Lee T 2003 A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations J. Comput. Chem. 24 1999-2012
67. Lee MC, Duan Y 2004 Distinguish protein decoys by using a scoring function based on a new Amber force field, short molecular dynamics simulations, and the generalized Born solvent model Proteins 55 620-634 (Pubitemid 38620087)
68. Jakalian A, Bush BL, Jack DB, Bayly CI 2000 Fast, efficient generation of high-quality atomic charges. AM1-BCC model: I. Method J. Comput. Chem. 21 132-146
69. Jakalian A, Jack DB, Bayly CI 2002 Fast, efficient generation of high-quality atomic charges. AM1-BCC model: II. Parameterization and Validation J. Comput. Chem. 23 1623-1641 (Pubitemid 35330860)