Voltage-induced nonconductive pre-pores and metastable single pores in unmodified planar lipid bilayer

Biophysical Journal

Volumn 80, Issue 4, 2001, Pages 1829-1836

  Melikov, Kamran C ^a,b   Frolov, Vadim A ^a   Shcherbakov, Arseniy ^a   Samsonov, Andrey V ^a   Chizmadzhev, Yury A ^a   Chernomordik, Leonid V ^b  

^a FRUMKIN INSTITUTE OF PHYSICAL CHEMISTRY AND ELECTROCHEMISTRY   (Russian Federation)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL;

ARTICLE; CHANNEL GATING; ELECTRIC FIELD; ELECTRIC POTENTIAL; ION CONDUCTANCE; LIPID BILAYER; MEMBRANE MODEL; MOLECULAR DYNAMICS;

EID: 0035072557     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)76153-X     Document Type: Article

References (5)

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2. Akinlaja, J., and F. Sachs. 1998. The breakdown of cell membranes by electrical and mechanical stress. Biophys. J. 75:247-254.
3. Antonov, V. F., V. V. Petrov, A. A. Molnar, D. A. Predvoditelev, and A. S. Ivanov. 1980. The appearance of single-ion channels in unmodified lipid bilayer membranes at the phase transition temperature. Nature. 283:585-586.
4. Basanez, G., A. Nechushtan, O. Drozhinin, A. Chanturiya, E. Choe, S. Tutt, K. A. Wood, Y. Hsu, J. Zimmerberg, and R. J. Youle. 1999. Bax, but not Bcl-xL, decreases the lifetime of planar phospholipid bilayer membranes at subnanomolar concentrations. Proc. Natl. Acad. Sci. U.S.A. 96:5492-5497.
5. Bechinger, B. 1999. The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy. Biochim. Biophys. Acta. 1462:157-183.