메뉴 건너뛰기




Volumn 4, Issue 4, 2012, Pages 390-402

The putative G-protein coupled estrogen receptor agonist G-1 suppresses proliferation of ovarian and breast cancer cells in a GPER-independent manner

Author keywords

Breast cancer; Estrogen receptors; G 1; G15; GPR30 GPER; Ovarian cancer

Indexed keywords

1 [4 (6 BROMOBENZO[1,3]DIOXOL 5YL) 3A,4,5,9B TETRAHYDRO 3H CYCLOPENTA [C]QUINOLIN 8 YL] ETHANONE; ANTINEOPLASTIC AGENT; G 1; G PROTEIN COUPLED RECEPTOR 30; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84868010705     PISSN: None     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (35)
  • 2
    • 4344605682 scopus 로고    scopus 로고
    • Estrogen, Progesterone and Epithelial Ovarian Cancer
    • Ho S-M. Estrogen, Progesterone and Epithelial Ovarian Cancer. Reproductive Biology and Endocrinology 2003; 1: 73.
    • (2003) Reproductive Biology and Endocrinology , vol.1 , pp. 73
    • Ho, S.-M.1
  • 3
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P, Pang Y, Filardo EJ, Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 2005; 146: 624-632.
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 4
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo EJ, Quinn JA, Bland KI, Frackelton AR Jr. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Molecular Endocrinology 2000; 14: 1649-1660.
    • (2000) Molecular Endocrinology , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton Jr., A.R.4
  • 5
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • Revankar CM, Cimino CF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005; 307: 1625-1630.
    • (2005) Science , vol.307 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, C.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 6
    • 77950407928 scopus 로고    scopus 로고
    • Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling
    • Kang L, Zhang X, Xie Y, Tu Y, Wang D, Liu Z, Wang ZY. Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling. Molecular Endocrinology 2010; 24: 709-721.
    • (2010) Molecular Endocrinology , vol.24 , pp. 709-721
    • Kang, L.1    Zhang, X.2    Xie, Y.3    Tu, Y.4    Wang, D.5    Liu, Z.6    Wang, Z.Y.7
  • 7
    • 63849261057 scopus 로고    scopus 로고
    • G Protein-Coupled Receptor 30: Estrogen Receptor or Collaborator?
    • Levin ER. G Protein-Coupled Receptor 30: Estrogen Receptor or Collaborator? Endocrinology 2009; 150: 1563-1565.
    • (2009) Endocrinology , vol.150 , pp. 1563-1565
    • Levin, E.R.1
  • 8
    • 33747841976 scopus 로고    scopus 로고
    • Nature of functional estrogen receptors at the plasma membrane
    • Pedram A, Razandi M, and Levin ER. Nature of functional estrogen receptors at the plasma membrane. Molecular Endocrinology 2006; 20: 1996-2009.
    • (2006) Molecular Endocrinology , vol.20 , pp. 1996-2009
    • Pedram, A.1    Razandi, M.2    Levin, E.R.3
  • 9
    • 82155173499 scopus 로고    scopus 로고
    • The G-protein-coupled estrogen receptor GPER in health and disease
    • Prossnitz ER, Barton M. The G-protein-coupled estrogen receptor GPER in health and disease. Nature Review Endocrinology 2011; 7: 715-726.
    • (2011) Nature Review Endocrinology , vol.7 , pp. 715-726
    • Prossnitz, E.R.1    Barton, M.2
  • 13
    • 77949566651 scopus 로고    scopus 로고
    • Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice
    • Balhuizen A, Kumar R, Amisten S, Lundquist I, Salehi A. Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice. Molecular & Cellular Endocrinology 2010; 320: 16-24.
    • (2010) Molecular & Cellular Endocrinology , vol.320 , pp. 16-24
    • Balhuizen, A.1    Kumar, R.2    Amisten, S.3    Lundquist, I.4    Salehi, A.5
  • 15
    • 77955711650 scopus 로고    scopus 로고
    • Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest
    • Chan QK, Lam HM, Ng CF, Lee AY, Chan ES, Ng HK, Ho SM, Lau KM. Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest. Cell Death and Differentiation 2010; 17: 1511-1523.
    • (2010) Cell Death and Differentiation , vol.17 , pp. 1511-1523
    • Chan, Q.K.1    Lam, H.M.2    Ng, C.F.3    Lee, A.Y.4    Chan, E.S.5    Ng, H.K.6    Ho, S.M.7    Lau, K.M.8
  • 16
    • 84857837160 scopus 로고    scopus 로고
    • Molecular Pathogenesis of Granulosa Cell Tumors of the Ovary
    • Jamieson S, Fuller PJ. Molecular Pathogenesis of Granulosa Cell Tumors of the Ovary. Endocrine Reviews 2012; 33: 109-144.
    • (2012) Endocrine Reviews , vol.33 , pp. 109-144
    • Jamieson, S.1    Fuller, P.J.2
  • 18
    • 56649109916 scopus 로고    scopus 로고
    • Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: A metastasis model cell line
    • Imai M, Muraki M, Takamatsu K, Saito H, Seiki M, Takahashi Y. Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line. BMC Cancer 2008; 8: 319.
    • (2008) BMC Cancer , vol.8 , pp. 319
    • Imai, M.1    Muraki, M.2    Takamatsu, K.3    Saito, H.4    Seiki, M.5    Takahashi, Y.6
  • 19
    • 34748862634 scopus 로고    scopus 로고
    • Expression of G protein-coupled receptor 30 in the hamster ovary: Differential regulation by gonadotropins and steroid hormones
    • Wang C, Prossnitz ER, Roy SK. Expression of G protein-coupled receptor 30 in the hamster ovary: differential regulation by gonadotropins and steroid hormones. Endocrinology 2007; 148: 4853-4864.
    • (2007) Endocrinology , vol.148 , pp. 4853-4864
    • Wang, C.1    Prossnitz, E.R.2    Roy, S.K.3
  • 20
    • 50449104180 scopus 로고    scopus 로고
    • G protein- coupled receptor 30 expression Is required for estrogen stimulation of primordial follicle formation in the hamster ovary
    • Wang C, Prossnitz ER, Roy SK. G protein- coupled receptor 30 expression Is required for estrogen stimulation of primordial follicle formation in the hamster ovary. Endocrinology 2008:149: 4452-4461.
    • (2008) Endocrinology , vol.149 , pp. 4452-4461
    • Wang, C.1    Prossnitz, E.R.2    Roy, S.K.3
  • 21
    • 79960705272 scopus 로고    scopus 로고
    • Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells
    • Sharma G, Prossnitz ER. Mechanisms of estradiol-induced insulin secretion by the G protein-coupled estrogen receptor GPR30/GPER in pancreatic beta-cells. Endocrinology 2011; 152: 3030-3039.
    • (2011) Endocrinology , vol.152 , pp. 3030-3039
    • Sharma, G.1    Prossnitz, E.R.2
  • 22
    • 79957735539 scopus 로고    scopus 로고
    • Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat
    • Lindsey SH, Carver KA, Prossnitz ER, Chappell MC. Vasodilation in response to the GPR30 agonist G-1 is not different from estradiol in the mRen2.Lewis female rat. Journal of Cardiovascular Pharmacology 2011; 57: 598-603.
    • (2011) Journal of Cardiovascular Pharmacology , vol.57 , pp. 598-603
    • Lindsey, S.H.1    Carver, K.A.2    Prossnitz, E.R.3    Chappell, M.C.4
  • 23
    • 79960133918 scopus 로고    scopus 로고
    • Involvement of epidermal growth factor receptor signaling in estrogen inhibition of oocyte maturation mediated through the G protein-coupled estrogen receptor (GPER) in zebrafish (Daniorerio)
    • Peyton C, Thomas P. Involvement of epidermal growth factor receptor signaling in estrogen inhibition of oocyte maturation mediated through the G protein-coupled estrogen receptor (GPER) in zebrafish (Daniorerio). Biology of Reproduction 2011; 85: 42-50.
    • (2011) Biology of Reproduction , vol.85 , pp. 42-50
    • Peyton, C.1    Thomas, P.2
  • 25
    • 79959870180 scopus 로고    scopus 로고
    • Retrograde transport of the transmembrane estrogen receptor, G-protein-coupled-receptor-30 (GPR30/GPER) from the plasma membrane towards the nucleus
    • Cheng SB, Graeber CT, Quinn JA, Filardo EJ. Retrograde transport of the transmembrane estrogen receptor, G-protein-coupled-receptor-30 (GPR30/GPER) from the plasma membrane towards the nucleus. Steroids 2011; 76: 892-896.
    • (2011) Steroids , vol.76 , pp. 892-896
    • Cheng, S.B.1    Graeber, C.T.2    Quinn, J.A.3    Filardo, E.J.4
  • 26
    • 34347238583 scopus 로고    scopus 로고
    • Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane
    • Filardo E, Quinn J, Pang Y, Graeber C, Shaw S, Dong J. Thomas P. Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane. Endocrinology 2007; 148: 3236-3245.
    • (2007) Endocrinology , vol.148 , pp. 3236-3245
    • Filardo, E.1    Quinn, J.2    Pang, Y.3    Graeber, C.4    Shaw, S.5    Dong, J.6    Thomas, P.7
  • 27
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
    • Filardo EJ, Quinn JA, Frackelton AR Jr, Bland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Molecular Endocrinology 2002; 16: 70-84.
    • (2002) Molecular Endocrinology , vol.16 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Frackelton Jr., A.R.3    Bland, K.I.4
  • 28
    • 0031282001 scopus 로고    scopus 로고
    • Identification of a Gene (GPR30) with Homology to the G-Protein-Coupled Receptor Superfamily Associated with Estrogen Receptor Expression in Breast Cancer
    • Carmeci C, Thompson DA, Ring HZ, Francke U, Weigel RJ. Identification of a Gene (GPR30) with Homology to the G-Protein-Coupled Receptor Superfamily Associated with Estrogen Receptor Expression in Breast Cancer. Genomics 1997; 45: 607-617.
    • (1997) Genomics , vol.45 , pp. 607-617
    • Carmeci, C.1    Thompson, D.A.2    Ring, H.Z.3    Francke, U.4    Weigel, R.J.5
  • 34
    • 84862912924 scopus 로고    scopus 로고
    • Nuclear estrogen receptor-mediated Notch signaling and GPR30-mediated PI3K/AKT signaling in the regulation of endometrial cancer cell proliferation
    • Wei Y, Zhang Z, Liao H, Wu L, Wu X, Zhou D, Xi X, Zhu Y, Fen Y. Nuclear estrogen receptor-mediated Notch signaling and GPR30-mediated PI3K/AKT signaling in the regulation of endometrial cancer cell proliferation. Oncology Report 2012; 27: 504-510.
    • (2012) Oncology Report , vol.27 , pp. 504-510
    • Wei, Y.1    Zhang, Z.2    Liao, H.3    Wu, L.4    Wu, X.5    Zhou, D.6    Xi, X.7    Zhu, Y.8    Fen, Y.9
  • 35
    • 0031857866 scopus 로고    scopus 로고
    • Hormonal control of the cell cycle in ovarian cells: Proliferation versus differentiation
    • Robker RL, Richards JS. Hormonal control of the cell cycle in ovarian cells: proliferation versus differentiation. Biology of Reproduction 1998; 59: 476-482.
    • (1998) Biology of Reproduction , vol.59 , pp. 476-482
    • Robker, R.L.1    Richards, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.