Retrograde transport of the transmembrane estrogen receptor, G-protein-coupled-receptor-30 (GPR30/GPER) from the plasma membrane towards the nucleus

Steroids

Volumn 76, Issue 9, 2011, Pages 892-896

  Cheng, Shi Bin ^a   Graeber, Carl T ^a   Quinn, Jeffrey A ^a   Filardo, Edward J ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Constitutive endocytosis; Desensitization; Endosome; GPR30 GPER; Perinuclear; Trafficking

Indexed keywords

CLATHRIN; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTRADIOL; G PROTEIN COUPLED RECEPTOR 30;

ARTICLE; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELL NUCLEUS; CELL STIMULATION; CELL STRAIN HEK293; CELL SURFACE; CELL TRANSPORT; COATED VESICLE; EMBRYO; ENDOCYTOSIS; ENDOSOME; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MEMBRANE TRANSPORT; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ADENOCARCINOMA; BREAST NEOPLASMS; CELL MEMBRANE; CELL NUCLEUS; CELLS, CULTURED; HUMANS; MAMMARY GLANDS, HUMAN; NUCLEAR ENVELOPE; PROTEIN TRANSPORT; RECEPTORS, G-PROTEIN-COUPLED;

EID: 79959870180     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2011.02.018     Document Type: Article

References (30)

1. Filardo EJ, Graeber CT, Quinn JA, Resnick MB, Giri D, DeLellis RA, et al. Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression. Clin Cancer Res 2006;12:6359-66. (Pubitemid 44799705)
2. Kuo WH, Chang LY, Liu DL, Hwa HL, Lin JJ, Lee PH, et al. The interactions between GPR30 and the major biomarkers in infiltrating ductal carcinoma of the breast in an Asian population. Taiwan J Obstet Gynecol 2007;46(2):135-45. Erratum in: Taiwan J. Obstet Gynecol 2007 Sep 46(3): 320-1.
3. Smith HO, Leslie KK, Singh M, Qualls CR, Revankar CM, Joste NE, et al. GPR30: a novel indicator of poor survival for endometrial carcinoma. Am J Obstet Gynecol 2007;196(386):e1-9.
4. Smith HO, Arias-Pulido H, Kuo DY, Howard T, Qualls CR, Lee SJ, et al. GPR30 predicts poor survival for ovarian cancer. Gynecol Oncol 2009;114:465-71.
5. Thomas P, Pang Y, Filardo EJ, Dong J. Identity of a membrane estrogen receptor coupled to a G-protein in human breast cancer cells. Endocrinology 2005;146:624-32. (Pubitemid 40129818)
6. Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005;307:1625-30. (Pubitemid 40354745)
7. Filardo EJ, Quinn JA, Frackelton Jr AR, Bland KI. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol 2002;16:70-84.
8. Filardo EJ, Quinn JA, Graeber CT. Evidence supporting a role for GPR30, an orphan member of the G-protein-coupled receptor superfamily in rapid estrogen signaling. In: Watson CM, editor. Identification of membrane-associated steroid hormone receptors. NY: Kluwer Press; 2003.
9. Quinn JA, Graeber CT, Frackelton Jr AR, Kim M, Schwarzbauer JE, Filardo EJ. Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor GPR30. Mol Endocrinol 2009;23:1052-64.
10. Filardo EJ, Quinn JA, Bland KI, Frackelton Jr AR. Estrogen-induced activation of Erk-1 and Erk-2 requires the G-protein-coupled receptor homologue, GPR30, and occurs via transactivation of the EGF receptor through release of HB-EGF. Mol Endocrinol 2000;14:1649-60.
11. Filardo EJ, Thomas P. GPR30: a seven-transmembrane-spanning estrogen receptor that triggers EGF release. Trends Endocrin Metab 2005;16:362-7. (Pubitemid 41338741)
12. Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999;402(6764):884-8.
13. Carpenter G. The EGF receptor: a nexus for trafficking and signaling. Bioessays 2000:697-707. (Pubitemid 30613301)
14. Benovic JL. Regulation of G protein coupled receptor function and expression: receptor biochemistry and methodology. Wiley-Liss; 1999.
15. Marchese A, Paing MM, Temple BR, Trejo J. G protein-coupled receptor sorting to endosomes and lysosomes. Annu Rev Pharmacol Toxicol 2008;48:601-29. (Pubitemid 351738165)
16. Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem 1999;274(45):32248-57.
17. Innamorati G, Sadeghi HM, Tran NT, Birnbaumer M. A serine cluster prevents recycling of the V2 vasopressin receptor. Proc Natl Acad Sci USA 1998;95(5):2222-6. (Pubitemid 28145922)
18. Innamorati G, Le Gouill C, Balamotis M, Birnbaumer M. The long and the short cycle, alternative intracellular routes for trafficking of G-protein-coupled receptors. J Biol Chem 2001;276(16):13096-103.
19. Filardo E, Quinn J, Pang Y, Graeber C, Shaw S, Dong J, et al. Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane. Endocrinology 2007;148:3236-45. (Pubitemid 46997004)
20. Levin ER. G protein-coupled receptor 30: estrogen receptor or collaborator? Endocrinology 2009;150(April (4)):1563-5.
21. Otto C, Rohde-Schulz B, Schwarz G, Fuchs I, Klewer M, Brittain D, et al. G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol. Endocrinology 2008;149(10):4846-56.
22. Tarasova NI, Stauber RH, Michejda CJ. Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4. J Biol Chem 1998;26(273(26)):15883-6. (Pubitemid 28311348)
23. Connolly CN, Uren JM, Thomas P, Gorrie GH, Gibson A, Smart TG, et al. Subcellular localization and endocytosis of homomeric gamma2 subunit splice variants of gamma-aminobutyric acid type A receptors. Mol Cell Neurosci 1999;13(4):259-71. (Pubitemid 29246852)
24. Zhang Y, Foudi A, Geay JF, Berthebaud M, Buet D, Jarrier P, et al. Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells. Stem Cells 2004;22(6):1015-29. (Pubitemid 39507088)
25. Xu H, Qin S, Carrasco GA, Dai Y, Filardo EJ, Prossnitz ER, et al. Extra-nuclear estrogen receptor GPR30 regulates serotonin function in rat hypothalamus. Neuroscience 2009;158(4):1599-607.
26. McDonald NA, Henstridge CM, Connolly CN, Irving AJ. An essential role for constitutive endocytosis, but not activity, in the axonal targeting of the CB1 cannabinoid receptor. Mol Pharmacol 2007;71(4):976-84. (Pubitemid 46457002)
27. Sesack SR, Aoki C, Pickel VM. Ultrastructural localization of D2 receptor-like immunoreactivity in midbrain dopamine neurons and their striatal targets. J Neurosci 1994;14(1):88-106.
28. Cornea-Hébert V, Riad M, Wu C, Singh SK, Descarries L. Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat. J Comp Neurol 1999;409(2):187-209. (Pubitemid 29264253)
29. Kostich WA, Grzanna R, Lu NZ, Largent BL. Immunohistochemical visualization of corticotropin-releasing factor type 1 (CRF1) receptors in monkey brain. J Comp Neurol 2004;478(2):111-25. (Pubitemid 39166662)
30. Seifert R, Wenzel-Seifert K. Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors. Naunyn Schmiedebergs Arch Pharmacol 2002;366(5):381-416. (Pubitemid 35251788)