Effect of mosapride on prednisolone-induced gastric mucosal injury and gastric-emptying disorder in dog

Journal of Veterinary Medical Science

Volumn 74, Issue 9, 2012, Pages 1103-1108

  Tsukamoto, Atsushi ^a   Ohno, Koichi ^a   Maeda, Shingo ^a   Nakashima, Ko ^a   Fukushima, Kenjiro ^a   Fujino, Yasuhito ^a   Hori, Masatoshi ^a   Tsujimoto, Hajime ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

5 HT4R agonist; Corticosteroid; Gastric ulcer; Gastrointestinal adverse event; Prokinetic agent

Indexed keywords

BENZAMIDE DERIVATIVE; CARBON; GASTROINTESTINAL AGENT; MORPHOLINE DERIVATIVE; MOSAPRIDE; OCTANOIC ACID; OCTANOIC ACID DERIVATIVE; PREDNISOLONE; PRIMER DNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; BREATH ANALYSIS; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CROSSOVER PROCEDURE; DOG; DOG DISEASE; DRUG EFFECT; FEMALE; GENETICS; MALE; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH DISEASE; STOMACH EMPTYING; STOMACH MUCOSA; TIME;

ANIMALS; BENZAMIDES; BREATH TESTS; CAPRYLATES; CARBON ISOTOPES; CROSS-OVER STUDIES; DNA PRIMERS; DOG DISEASES; DOGS; FEMALE; GASTRIC EMPTYING; GASTRIC MUCOSA; GASTROINTESTINAL AGENTS; MALE; MORPHOLINES; PREDNISOLONE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH DISEASES; TIME FACTORS;

EID: 84867910879     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.12-0066     Document Type: Article

References (33)

1. Arakawa, T., Higuchi, K., Fukuda, T., Matsumoto, T., Kobayashi, K. and Kuroki, T. 1998. Recurrence of ulcers and inflammation]. Nippon Naika Gakkai Zasshi 87: 753-761 (in Japanese). [Medline] [CrossRef]
2. Balch, A. and Mackin, A. 2007. Canine immune-mediated hemolytic anemia: treatment and prognosis. Compend. Contin. Educ. Vet. 29: 230-238; quiz 239. [Medline]
3. Bickel, M. and Kauffman, G. L. Jr. 1981. Gastric gel mucus thickness: effect of distention, 16,16-dimethyl prostaglandin e2, and carbenoxolone. Gastroenterology 80: 770-775. [Medline]
4. Borovikova, L. V., Ivanova, S., Zhang, M., Yang, H., Botchkina, G. I., Watkins, L. R., Wang, H., Abumrad, N., Eaton, J. W. and Tracey, K. J. 2000. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 405: 458-462. [Medline] [CrossRef]
5. Curran, M. P. and Robinson, D. M. 2008. Mosapride in gastrointestinal disorders. Drugs 68: 981-991. [Medline] [CrossRef]
6. Fujimura, J., Haruma, K., Hata, J., Yamanaka, H., Sumii, K. and Kajiyama, G. 1994. Quantitation of duodenogastric reflux and antral motility by color Dopplerultrasonography. Study in healthy volunteers and patients with gastric ulcer. Scand. J. Gastroenterol. 29: 897-902. [Medline] [CrossRef]
7. 4 receptor agonist mosapride attenuates NSAID-induced gastric mucosal damage. J. Gastroenterol. 45: 179-186. [Medline] [CrossRef]
8. Ghoos, Y. F., Maes, B. D., Geypens, B. J., Mys, G., Hiele, M. I., Rutgeerts, P. J. and Vantrappen, G. 1993. Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Gastroenterology 104: 1640-1647. [Medline]
9. Gudis, K. and Sakamoto, C. 2005. The role of cyclooxygenase in gastric mucosal protection. Dig. Dis. Sci. 50: S16-S23. [Medline] [CrossRef]
10. Hamlet, A., Lindholm, C., Nilsson, O. and Olbe, L. 1998. Aspirin-induced gastritis, like Helicobacter pylori-induced gastritis disinhibits acid secretion in humans: relation to cytokine expression. Scand. J. Gastroenterol. 33: 346-356. [Medline] [CrossRef]
11. Heather Graham, A. and Leib, M. S. 2009. Effects of prednisone alone or prednisone with ultralow-dose aspirin on the gastroduodenal mucosa of healthy dogs. J. Vet. Intern. Med. 23: 482-487. [Medline] [CrossRef]
12. Kawahara, R., Yasuda, M., Hashimura, H., Amagase, K., Kato, S. and Takeuchi, K. 2011. Activation of α7 nicotinic acetylcholine receptors ameliorates indomethacin-induced small intestinal ulceration in mice. Eur. J. Pharmacol. 650: 411-417. [Medline] [CrossRef]
13. Konturek, S. J., Radecki, T., Brzozowski, T., Piastucki, I., Dembinski, A., Dembinska-Kiec, A., Zmuda, A., Gryglewski, R. and Gregory, H. 1981. Gastric cytoprotection by epidermal growth factor. Role of endogenous prostaglandins and DNA synthesis. Gastroenterology 81: 438-443. [Medline]
14. Lanza, F. L., Royer, G. L. Jr. and Nelson, R. S. 1980. Endoscopic evaluation of the effects of aspirin, buffered aspirin, and entericcoated aspirin on gastric and duodenal mucosa. N. Engl. J. Med. 303: 136-138. [Medline] [CrossRef]
15. Main, I. H. and Whittle, B. J. 1973. The effects E and A prostaglandins on gastric mucosal blood flow and acid secretion in the rat. Br. J. Pharmacol. 49: 428-436. [Medline]
16. Nobuhara, Y., Ueki, S. and Takeuchi, K. 1985. Influence of prednisolone on gastric alkaline response in rat stomach. A possible explanation for steroid-induced gastric lesion. Dig. Dis. Sci. 30: 1166-1173. [Medline] [CrossRef]
17. 4 receptor agonist (mosapride citrate). Nippon Rinsho 64: 1491-1494 (in Japanese). [Medline]
18. Ohno, K., Yokoyama, Y., Nakashima, K., Setoguchi, A., Fujino, Y. and Tsujimoto, H. 2006. C-reactive protein concentration in canine idiopathic polyarthritis. J. Vet. Med. Sci. 68: 1275-1279. [Medline] [CrossRef]
19. Olivry, T., Foster, A. P., Mueller, R. S., McEwan, N. A., Chesney, C. and Williams, H. C. 2010. Interventions for atopic dermatitis in dogs: a systematic review of randomized controlled trials. Vet. Dermatol. 21: 4-22. [Medline] [CrossRef]
20. Pavlov, V. A. and Tracey, K. J. 2005. The cholinergic antiinflammatory pathway. Brain Behav. Immun. 19: 493-499. [Medline] [CrossRef]
21. Phillips, J. D., Stelzner, M., Zeng, H., Kelly, R. E. Jr. and Fonkalsrud, E. W. 1991. Alterations in gastrointestinal motility during postoperative acute corticosteroid withdrawal. Am. J. Surg. 162: 251-255. [Medline] [CrossRef]
22. Rohrer, C. R., Hill, R. C., Fischer, A., Fox, L. E., Schaer, M., Ginn, P. E., Casanova, J. M. and Burrows, C. F. 1999. Gastric hemorrhage in dogs given high doses of methylprednisolone sodium succinate. Am. J. Vet. Res. 60: 977-981. [Medline]
23. Rosas-Ballina, M. and Tracey, K. J. 2009. Cholinergic control of inflammation. J. Intern. Med. 265: 663-679. [Medline] [Cross-Ref]
24. Sanders, K. M. 1984. Role of prostaglandins in regulating gastric motility. Am. J. Physiol. 247: G117-G126. [Medline]
25. Takeuchi, K. and Nobuhara, Y. 1985. Inhibition of gastric motor activity by 16,16-dimethyl prostaglandin E2. A possible explanation of cytoprotection. Dig. Dis. Sci. 30: 1181-1188. [Medline] [CrossRef]
26. Tanigawa, T., Pai, R., Arakawa, T., Higuchi, K. and Tarnawski, A. S. 2005. TGF-beta signaling pathway: its role in gastrointestinal pathophysiology and modulation of ulcer healing. J. Physiol. Pharmacol. 56: 3-13. [Medline]
27. Tarnawski, A. S. 2005. Cellular and molecular mechanisms of gastrointestinal ulcer healing. Dig. Dis. Sci. 50(Suppl. 1): S24-S33. [Medline] [CrossRef]
28. Tsukamoto, A., Ohno, K., Tsukagoshi, T., Maeda, S., Nakashima, K., Fukushima, S., Fujino, Y., Takeuchi, Y. and Tsujimoto, H. 2011. Ultrasonographic evaluation of vincristine-induced gastric hypomotility and the prokinetic effect of mosapride in dogs. J. Vet. Intern. Med. 25: 1461-1464. [Medline] [CrossRef]
29. 4R agonist mosapride on canine gastric motility. J. Vet. Med. Sci. 73: 1635-1637. [Medline] [CrossRef]
30. Ward, D. M., Leib, M. S., Johnston, S. A. and Marini, M. 2003. The effect of dosing interval on the efficacy of misoprostol in the prevention of aspirin-induced gastric injury. J. Vet. Intern. Med. 17: 282-290. [Medline] [CrossRef]
31. 13C-octanoic acid breath test for assessment of solid-phase gastric emptying in dogs. Am. J. Vet. Res. 62: 1939-1944. [Medline] [CrossRef]
32. Yasuda, M., Kawahara, R., Hashimura, H., Yamanaka, N., Iimori, M., Amagase, K., Kato, S. and Takeuchi, K. 2011. Dopamine D-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors. J. Pharmacol. Sci. 116: 274-282. [Medline] [CrossRef]
33. 2 receptor antagonist properties. Arch. Int. Pharmacodyn. Ther. 300: 51-67. [Medline]