Dopamine D2-receptor antagonists ameliorate indomethacin-induced small intestinal ulceration in mice by activating α7 nicotinic acetylcholine receptors

Journal of Pharmacological Sciences

Volumn 116, Issue 3, 2011, Pages 274-282

  Yasuda, Masashi ^a   Kawahara, Ryoji ^a   Hashimura, Hiroshi ^a   Yamanaka, Naoki ^a   Iimori, Maho ^a   Amagase, Kikuko ^a   Kato, Shinichi ^a   Takeuchi, Koji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Chemokine; Indomethacin; Small intestinal ulceration; 7 nicotinic acetylcholine receptor

Indexed keywords

BUNGAROTOXIN RECEPTOR; CHEMOKINE; DOMPERIDONE; DOPAMINE; DOPAMINE 2 RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; METHYLLYCACONITINE; METOCLOPRAMIDE; MYELOPEROXIDASE; ANTIULCER AGENT; DOPAMINE RECEPTOR BLOCKING AGENT; GASTROINTESTINAL AGENT; INDOMETACIN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMOKINE GENE; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE; GENE EXPRESSION REGULATION; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; INTESTINE INJURY; INTESTINE ULCER; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PHARMACOLOGICAL STIMULATION; PROPHYLAXIS; RAT; SMALL INTESTINE HEMORRHAGE; ULCEROGENESIS; UPREGULATION; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG ANTAGONISM; DRUG POTENTIATION; ENTEROPATHY; GASTROINTESTINAL MOTILITY; HOSPITALIZATION; METABOLISM; PATHOLOGY; SMALL INTESTINE; ULCER; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; DOMPERIDONE; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL AGENTS; GASTROINTESTINAL MOTILITY; GENE EXPRESSION REGULATION; INDOMETHACIN; INTESTINAL DISEASES; INTESTINE, SMALL; MALE; METOCLOPRAMIDE; MICE; MICE, INBRED C57BL; NICOTINIC ANTAGONISTS; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; RECEPTORS, NICOTINIC; SEVERITY OF ILLNESS INDEX; ULCER;

EID: 79960414964     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.11037FP     Document Type: Article

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