Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 43, 2012, Pages 17579-17584

  Roy, Anindita ^a   Cowan, Gillian ^a   Mead, Adam J ^b   Filippi, Sarah ^a   Bohn, Georg ^a   Chaidos, Aristeidis ^a   Tunstall, Oliver ^a   Chan, Jerry K Y ^c,d   Choolani, Mahesh ^c,d   Bennett, Phillip ^a   Kumar, Sailesh ^a   Atkinson, Deborah ^b   Wyatt Ashmead, Josephine ^e   Hu, Ming ^a   Stumpf, Michael P H ^a   Goudevenou, Katerina ^a   O'Connor, David ^a   Chou, Stella T ^f   Weiss, Mitchell J ^f   Karadimitris, Anastasios ^a   Jacobsen, Sten Eirik ^b   Vyas, Paresh ^g   Roberts, Irene ^a   more..

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

^e IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^f CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^g UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Aneuploidy; Human fetus; Transient myeloproliferative disorder

Indexed keywords

CD19 ANTIGEN; CD34 ANTIGEN; CD45RA ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; INTERLEUKIN 3 RECEPTOR; NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR ERG; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR RUNX1;

ARTICLE; B LYMPHOCYTE; CELL MATURATION; CLONOGENESIS; EXON; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN TISSUE; LIVER; LIVER HEMATOPOIETIC STEM CELL; LYMPHOID PROGENITOR CELL; LYMPHOPOIESIS; MEGAKARYOCYTE; PRIORITY JOURNAL; STEM CELL; TRISOMY 21;

CELL DIFFERENTIATION; CELL LINEAGE; DOWN SYNDROME; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELLS; HUMANS; LIVER;

EID: 84867909526     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1211405109     Document Type: Article

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