메뉴 건너뛰기




Volumn 189, Issue 9, 2012, Pages 4305-4312

The Yaa locus and IFN-α fine-tune germinal center B cell selection in murine systemic lupus erythematosus

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AUTOANTIBODY; CARDIOLIPIN ANTIBODY; DOUBLE STRANDED DNA ANTIBODY; IMMUNOGLOBULIN G; TOLL LIKE RECEPTOR 7;

EID: 84867903052     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200745     Document Type: Article
Times cited : (27)

References (44)
  • 1
    • 34247891509 scopus 로고    scopus 로고
    • Immunologically active autoantigens: The role of Toll-like receptors in the development of chronic inflammatory disease
    • DOI 10.1146/annurev.immunol.22.012703.104514
    • Marshak-Rothstein, A., and I. R. Rifkin. 2007. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annu. Rev. Immunol. 25: 419-441. (Pubitemid 46697913)
    • (2007) Annual Review of Immunology , vol.25 , pp. 419-441
    • Marshak-Rothstein, A.1    Rifkin, I.R.2
  • 3
    • 33748472865 scopus 로고    scopus 로고
    • Toll-like Receptor 7 and TLR9 Dictate Autoantibody Specificity and Have Opposing Inflammatory and Regulatory Roles in a Murine Model of Lupus
    • DOI 10.1016/j.immuni.2006.07.013, PII S1074761306003906
    • Christensen, S. R., J. Shupe, K. Nickerson, M. Kashgarian, R. A. Flavell, and M. J. Shlomchik. 2006. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25: 417-428. (Pubitemid 44354217)
    • (2006) Immunity , vol.25 , Issue.3 , pp. 417-428
    • Christensen, S.R.1    Shupe, J.2    Nickerson, K.3    Kashgarian, M.4    Flavell, R.A.5    Shlomchik, M.J.6
  • 5
    • 33745168605 scopus 로고    scopus 로고
    • Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
    • DOI 10.1126/science.1124978
    • Pisitkun, P., J. A. Deane, M. J. Difilippantonio, T. Tarasenko, A. B. Satterthwaite, and S. Bolland. 2006. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 312: 1669-1672. (Pubitemid 43902669)
    • (2006) Science , vol.312 , Issue.5780 , pp. 1669-1672
    • Pisitkun, P.1    Deane, J.A.2    Difilippantonio, M.J.3    Tarasenko, T.4    Satterthwaite, A.B.5    Bolland, S.6
  • 6
    • 36048962438 scopus 로고    scopus 로고
    • Control of Toll-like Receptor 7 Expression Is Essential to Restrict Autoimmunity and Dendritic Cell Proliferation
    • DOI 10.1016/j.immuni.2007.09.009, PII S1074761307004906
    • Deane, J. A., P. Pisitkun, R. S. Barrett, L. Feigenbaum, T. Town, J. M. Ward, R. A. Flavell, and S. Bolland. 2007. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27: 801-810. (Pubitemid 350102256)
    • (2007) Immunity , vol.27 , Issue.5 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3    Feigenbaum, L.4    Town, T.5    Ward, J.M.6    Flavell, R.A.7    Bolland, S.8
  • 8
    • 49049120579 scopus 로고    scopus 로고
    • Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus
    • Santiago-Raber, M. L., S. Kikuchi, P. Borel, S. Uematsu, S. Akira, B. L. Kotzin, and S. Izui. 2008. Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus. J. Immunol. 181: 1556-1562.
    • (2008) J. Immunol. , vol.181 , pp. 1556-1562
    • Santiago-Raber, M.L.1    Kikuchi, S.2    Borel, P.3    Uematsu, S.4    Akira, S.5    Kotzin, B.L.6    Izui, S.7
  • 10
    • 65249143322 scopus 로고    scopus 로고
    • Interferon-alpha treatment of female (NZW x BXSB)F(1) mice mimics some but not all features associated with the Yaa mutation
    • Ramanujam, M., P. Kahn, W. Huang, H. Tao, M. P. Madaio, S. M. Factor, and A. Davidson. 2009. Interferon-alpha treatment of female (NZW x BXSB)F(1) mice mimics some but not all features associated with the Yaa mutation. Arthritis Rheum. 60: 1096-1101.
    • (2009) Arthritis Rheum. , vol.60 , pp. 1096-1101
    • Ramanujam, M.1    Kahn, P.2    Huang, W.3    Tao, H.4    Madaio, M.P.5    Factor, S.M.6    Davidson, A.7
  • 11
    • 2442661580 scopus 로고    scopus 로고
    • H knock-in transgene
    • Steeves, M. A., and T. N. Marion. 2004. Tolerance to DNA in (NZB x NZW)F1 mice that inherit an anti-DNA V(H) as a conventional micro H chain transgene but not as a V(H) knock-in transgene. J. Immunol. 172: 6568-6577. (Pubitemid 38669091)
    • (2004) Journal of Immunology , vol.172 , Issue.11 , pp. 6568-6577
    • Steeves, M.A.1    Marion, T.N.2
  • 12
  • 13
    • 0037121975 scopus 로고    scopus 로고
    • Anti-DNA B cells in MRL/1pr mice show altered differentiation and editing pattern
    • DOI 10.1084/jem.20021560
    • Li, Y., H. Li, D. Ni, and M. Weigert. 2002. Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern. J. Exp. Med. 196: 1543-1552. (Pubitemid 36026466)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.12 , pp. 1543-1552
    • Li, Y.1    Li, H.2    Ni, D.3    Weigert, M.4
  • 14
    • 0030997499 scopus 로고    scopus 로고
    • Editing disease-associated autoantibodies
    • DOI 10.1016/S1074-7613(00)80673-1
    • Chen, C., E. L. Prak, and M. Weigert. 1997. Editing disease-associated autoantibodies. Immunity 6: 97-105. (Pubitemid 27130219)
    • (1997) Immunity , vol.6 , Issue.1 , pp. 97-105
    • Chen, C.1    Prak, E.L.2    Weigert, M.3
  • 17
    • 4344597627 scopus 로고    scopus 로고
    • Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus
    • Ramanujam, M., X. Wang, W. Huang, L. Schiffer, C. Grimaldi, A. Akkerman, B. Diamond, M. P. Madaio, and A. Davidson. 2004. Mechanism of action of transmembrane activator and calcium modulator ligand interactor-Ig in murine systemic lupus erythematosus. J. Immunol. 173: 3524-3534. (Pubitemid 39142063)
    • (2004) Journal of Immunology , vol.173 , Issue.5 , pp. 3524-3534
    • Ramanujam, M.1    Wang, X.2    Huang, W.3    Schiffer, L.4    Grimaldi, C.5    Akkerman, A.6    Diamond, B.7    Madaio, M.P.8    Davidson, A.9
  • 18
    • 0041689676 scopus 로고    scopus 로고
    • Predominant autoantibody production by early human B cell precursors
    • DOI 10.1126/science.1086907
    • Wardemann, H., S. Yurasov, A. Schaefer, J. W. Young, E. Meffre, and M. C. Nussenzweig. 2003. Predominant autoantibody production by early human B cell precursors. Science 301: 1374-1377. (Pubitemid 37075812)
    • (2003) Science , vol.301 , Issue.5638 , pp. 1374-1377
    • Wardemann, H.1    Yurasov, S.2    Schaefer, A.3    Young, J.W.4    Meffre, E.5    Nussenzweig, M.C.6
  • 19
    • 83755195707 scopus 로고    scopus 로고
    • BAFF/APRIL inhibition decreases selection of naive but not antigen-induced autoreactive B cells in murine systemic lupus erythematosus
    • Huang, W., I. Moisini, R. Bethunaickan, R. Sahu, M. Akerman, D. Eilat, M. Lesser, and A. Davidson. 2011. BAFF/APRIL inhibition decreases selection of naive but not antigen-induced autoreactive B cells in murine systemic lupus erythematosus. J. Immunol. 187: 6571-6580.
    • (2011) J. Immunol. , vol.187 , pp. 6571-6580
    • Huang, W.1    Moisini, I.2    Bethunaickan, R.3    Sahu, R.4    Akerman, M.5    Eilat, D.6    Lesser, M.7    Davidson, A.8
  • 20
    • 70349750487 scopus 로고    scopus 로고
    • Cloning and expression of murine Ig genes from single B cells
    • Tiller, T., C. E. Busse, and H. Wardemann. 2009. Cloning and expression of murine Ig genes from single B cells. J. Immunol. Methods 350: 183-193.
    • (2009) J. Immunol. Methods , vol.350 , pp. 183-193
    • Tiller, T.1    Busse, C.E.2    Wardemann, H.3
  • 22
    • 77951739752 scopus 로고    scopus 로고
    • Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice
    • Ramanujam, M., R. Bethunaickan, W. Huang, H. Tao, M. P. Madaio, and A. Davidson. 2010. Selective blockade of BAFF for the prevention and treatment of systemic lupus erythematosus nephritis in NZM2410 mice. Arthritis Rheum. 62: 1457-1468.
    • (2010) Arthritis Rheum. , vol.62 , pp. 1457-1468
    • Ramanujam, M.1    Bethunaickan, R.2    Huang, W.3    Tao, H.4    Madaio, M.P.5    Davidson, A.6
  • 23
    • 0345016363 scopus 로고    scopus 로고
    • Chromatin Specificity of Anti-Double-Stranded DNA Antibodies and a Role for Arg Residues in the Third Complementarity-Determining Region of the Heavy Chain
    • Guth, A. M., X. Zhang, D. Smith, T. Detanico, and L. J. Wysocki. 2003. Chromatin specificity of anti-double-stranded DNA antibodies and a role for Arg residues in the third complementarity-determining region of the heavy chain. J. Immunol. 171: 6260-6266. (Pubitemid 37467249)
    • (2003) Journal of Immunology , vol.171 , Issue.11 , pp. 6260-6266
    • Guth, A.M.1    Zhang, X.2    Smith, D.3    Detanico, T.4    Wysocki, L.J.5
  • 24
    • 0029553058 scopus 로고
    • Immunoglobulin heavy chain gene replacement: A mechanism of receptor editing
    • DOI 10.1016/1074-7613(95)90064-0
    • Chen, C., Z. Nagy, E. L. Prak, and M. Weigert. 1995. Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing. Immunity 3: 747-755. (Pubitemid 26091148)
    • (1995) Immunity , vol.3 , Issue.6 , pp. 747-755
    • Chen, C.1    Nagy, Z.2    Prak, E.L.3    Weigert, M.4
  • 25
    • 0029059812 scopus 로고
    • Light chain contribution to specificity in anti-DNA antibodies
    • Ibrahim, S. M., M. Weigert, C. Basu, J. Erikson, and M. Z. Radic. 1995. Light chain contribution to specificity in anti-DNA antibodies. J. Immunol. 155: 3223-3233.
    • (1995) J. Immunol. , vol.155 , pp. 3223-3233
    • Ibrahim, S.M.1    Weigert, M.2    Basu, C.3    Erikson, J.4    Radic, M.Z.5
  • 26
    • 0030827382 scopus 로고    scopus 로고
    • Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: Localization to the T-B interface of the splenic follicle
    • DOI 10.1084/jem.186.8.1257
    • Mandik-Nayak, L., A. Bui, H. Noorchashm, A. Eaton, and J. Erikson. 1997. Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle. J. Exp. Med. 186: 1257-1267. (Pubitemid 27469021)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.8 , pp. 1257-1267
    • Mandik-Nayak, L.1    Bui, A.2    Noorchashm, H.3    Eaton, A.4    Erikson, J.5
  • 27
    • 0027532192 scopus 로고
    • B lymphocytes may escape tolerance by revising their antigen receptors
    • Radic, M. Z., J. Erikson, S. Litwin, and M. Weigert. 1993. B lymphocytes may escape tolerance by revising their antigen receptors. J. Exp. Med. 177: 1165-1173.
    • (1993) J. Exp. Med. , vol.177 , pp. 1165-1173
    • Radic, M.Z.1    Erikson, J.2    Litwin, S.3    Weigert, M.4
  • 28
    • 0037332072 scopus 로고    scopus 로고
    • Regulation of anti-phosphatidylserine antibodies
    • DOI 10.1016/S1074-7613(03)00026-8
    • Li, H., Y. Jiang, H. Cao, M. Radic, E. L. Prak, and M. Weigert. 2003. Regulation of anti-phosphatidylserine antibodies. Immunity 18: 185-192. (Pubitemid 36262994)
    • (2003) Immunity , vol.18 , Issue.2 , pp. 185-192
    • Li, H.1    Jiang, Y.2    Cao, H.3    Radic, M.4    Prak, E.L.5    Weigert, M.6
  • 29
    • 0027309585 scopus 로고
    • Comparative in vitro analysis of proliferation, Ig secretion, and Ig class switching by murine marginal zone and follicular B cells
    • Snapper, C. M., H. Yamada, D. Smoot, R. Sneed, A. Lees, and J. J. Mond. 1993. Comparative in vitro analysis of proliferation, Ig secretion, and Ig class switching by murine marginal zone and follicular B cells. J. Immunol. 150: 2737-2745. (Pubitemid 23127523)
    • (1993) Journal of Immunology , vol.150 , Issue.7 , pp. 2737-2745
    • Snapper, C.M.1    Yamada, H.2    Smoot, D.3    Sneed, R.4    Lees, A.5    Mond, J.J.6
  • 32
    • 34447098797 scopus 로고    scopus 로고
    • Multistep Pathogenesis of Autoimmune Disease
    • DOI 10.1016/j.cell.2007.06.033, PII S0092867407008380
    • Goodnow, C. C. 2007. Multistep pathogenesis of autoimmune disease. Cell 130: 25-35. (Pubitemid 47031326)
    • (2007) Cell , vol.130 , Issue.1 , pp. 25-35
    • Goodnow, C.C.1
  • 33
    • 1042292575 scopus 로고    scopus 로고
    • Germinal center checkpoints in B cell tolerance in 3H9 transgenic mice
    • DOI 10.1093/intimm/dxh035
    • Paul, E., J. Lutz, J. Erikson, and M. C. Carroll. 2004. Germinal center checkpoints in B cell tolerance in 3H9 transgenic mice. Int. Immunol. 16: 377-384. (Pubitemid 38195668)
    • (2004) International Immunology , vol.16 , Issue.2 , pp. 377-384
    • Paul, E.1    Lutz, J.2    Erikson, J.3    Carroll, M.C.4
  • 35
    • 48749089721 scopus 로고    scopus 로고
    • B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice
    • Wang, Y.-H., and B. Diamond. 2008. B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice. J. Clin. Invest. 118: 2896-2907.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2896-2907
    • Wang, Y.-H.1    Diamond, B.2
  • 36
    • 0035030376 scopus 로고    scopus 로고
    • Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
    • DOI 10.1016/S1074-7613(01)00126-1
    • Le Bon, A., G. Schiavoni, G. D'Agostino, I. Gresser, F. Belardelli, and D. F. Tough. 2001. Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14: 461-470. (Pubitemid 32441598)
    • (2001) Immunity , vol.14 , Issue.4 , pp. 461-470
    • Le, B.A.1    Schiavoni, G.2    D'Agostino, G.3    Gresser, I.4    Belardelli, F.5    Tough, D.F.6
  • 37
    • 32044460431 scopus 로고    scopus 로고
    • Cutting edge: Enhancement of antibody responses through direct stimulation of B and T cells by type I IFN
    • Le Bon, A., C. Thompson, E. Kamphuis, V. Durand, C. Rossmann, U. Kalinke, and D. F. Tough. 2006. Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN. J. Immunol. 176: 2074-2078. (Pubitemid 43201653)
    • (2006) Journal of Immunology , vol.176 , Issue.4 , pp. 2074-2078
    • Le, B.A.1    Thompson, C.2    Kamphuis, E.3    Durand, V.4    Rossmann, C.5    Kalinke, U.6    Tough, D.F.7
  • 38
    • 70249131137 scopus 로고    scopus 로고
    • Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells
    • Cucak, H., U. Yrlid, B. Reizis, U. Kalinke, and B. Johansson-Lindbom. 2009. Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells. Immunity 31: 491-501.
    • (2009) Immunity , vol.31 , pp. 491-501
    • Cucak, H.1    Yrlid, U.2    Reizis, B.3    Kalinke, U.4    Johansson-Lindbom, B.5
  • 39
    • 37549049335 scopus 로고    scopus 로고
    • Anti-chromatin antibodies drive in vivo antigen-specific activation and somatic hypermutation of rheumatoid factor B cells at extrafollicular sites
    • Herlands, R. A., J. William, U. Hershberg, and M. J. Shlomchik. 2007. Anti-chromatin antibodies drive in vivo antigen-specific activation and somatic hypermutation of rheumatoid factor B cells at extrafollicular sites. Eur. J. Immunol. 37: 3339-3351.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 3339-3351
    • Herlands, R.A.1    William, J.2    Hershberg, U.3    Shlomchik, M.J.4
  • 41
  • 42
    • 3042548183 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
    • DOI 10.1084/jem.20031942
    • Boulé, M. W., C. Broughton, F. Mackay, S. Akira, A. Marshak-Rothstein, and I. R. Rifkin. 2004. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J. Exp. Med. 199: 1631-1640. (Pubitemid 38821996)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.12 , pp. 1631-1640
    • Boule, M.W.1    Broughton, C.2    Mackay, F.3    Akira, S.4    Marshak-Rothstein, A.5    Rifkin, I.R.6
  • 43
    • 0029562441 scopus 로고
    • The Yaa gene-mediated acceleration of murine lupus: Yaa- T cells from non-autoimmune mice collaborate with Yaa+ B cells to produce lupus autoantibodies in vivo
    • Fossati, L., E. S. Sobel, M. Iwamoto, P. L. Cohen, R. A. Eisenberg, and S. Izui. 1995. The Yaa gene-mediated acceleration of murine lupus: Yaa- T cells from non-autoimmune mice collaborate with Yaa+ B cells to produce lupus autoantibodies in vivo. Eur. J. Immunol. 25: 3412-3417.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3412-3417
    • Fossati, L.1    Sobel, E.S.2    Iwamoto, M.3    Cohen, P.L.4    Eisenberg, R.A.5    Izui, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.