Abnormal genetic and epigenetic changes in signal transducer and activator of transcription 4 in the pathogenesis of inflammatory bowel diseases

Digestive Diseases and Sciences

Volumn 57, Issue 10, 2012, Pages 2600-2607

  Kim, Seung Won ^a,b,c   Kim, Eun Soo ^a,b,d   Moon, Chang Mo ^a   Kim, Tae Il ^a   Kim, Won Ho ^a   Cheon, Jae Hee ^a,b  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University   (South Korea)

^c Ewha Womans University   (South Korea)

^d Keimyung University School of Medicine   (South Korea)

Author keywords

Crohn's disease; DNA methylation; Genetic polymorphism; Inflammatory bowel disease; Intestinal Bechet's disease; STAT4; Ulcerative colitis

Indexed keywords

GENOMIC DNA; MESSENGER RNA; RNA; STAT4 PROTEIN;

ALLELE; ARTICLE; BLOOD; CELL DIFFERENTIATION; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DNA METHYLATION; ENTERITIS; EPIGENETICS; GENETIC ANALYSIS; GENETIC RISK; GENOTYPE; HELPER CELL; HUMAN; HUMAN CELL; KOREA; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PYROSEQUENCING; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; COLON; DNA; DNA METHYLATION; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAT4 TRANSCRIPTION FACTOR;

EID: 84867893908     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-012-2199-z     Document Type: Article

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