Suppression of thymus- and activation-regulated chemokine (TARC/CCL17) production by 3-O-β-d-glucopyanosylspinasterol via blocking NF-κB and STAT1 signaling pathways in TNF-α and IFN-γ-induced HaCaT keratinocytes

Biochemical and Biophysical Research Communications

Volumn 427, Issue 2, 2012, Pages 236-241

  Jung, Mi Ra ^a   Lee, Tae Hoon ^a   Bang, Myun Ho ^a   Kim, Hakwon ^a   Son, Youngsook ^a   Chung, Dae Kyun ^a   Kim, Jiyoung ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Inflammation; Spinasterol glucose; TARC CCL17

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 3 O BETA DEXTRO GLUCOPYANOSYLSPINASTEROL; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA SPINASTEROL; C RAF INHIBITOR; GAMMA INTERFERON; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN INHIBITOR; RAF PROTEIN; STAT1 PROTEIN; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; HUMAN; HUMAN CELL; KERATINOCYTE; MEDICINAL PLANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEWARTIA KOREANA;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; CHEMOKINE CCL17; DERMATITIS, ATOPIC; DERMATOLOGIC AGENTS; HUMANS; INTERFERON-GAMMA; JANUS KINASE 2; KERATINOCYTES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-RAF; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STIGMASTEROL; TUMOR NECROSIS FACTOR-ALPHA;

STEWARTIA;

EID: 84867852346     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.08.087     Document Type: Article

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