A pharmacokinetic model of cis- and trans-permethrin disposition in rats and humans with aggregate exposure application

Toxicological Sciences

Volumn 130, Issue 1, 2012, Pages 33-47

  Tornero Velez, Rogelio ^a   Davis, Jimena ^a   Scollon, Edward J ^b   Starr, James M ^a   Setzer, R Woodrow ^a   Goldsmith, Michael Rock ^a   Chang, Daniel T ^a   Xue, Jianping ^a   Zartarian, Valerie ^a   DeVito, Michael J ^c   Hughes, Michael F ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Aggregate exposure model; PBPK; Pyrethroids

Indexed keywords

CIS ACTING ELEMENT; DELTAMETHRIN; PERMETHRIN; PYRETHROID; TRANS ACTING FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; BRAIN LEVEL; CONTROLLED STUDY; DIASTEREOISOMER; ENVIRONMENTAL EXPOSURE; HUMAN; HUMAN TISSUE; LIVER LEVEL; MALE; METABOLITE; NONHUMAN; POPULATION EXPOSURE; QUANTITATIVE ANALYSIS; RAT; SIMULATION; STEREOISOMERISM; TOXICOKINETICS;

ANIMALS; DIET; DRUG ADMINISTRATION ROUTES; ENVIRONMENTAL EXPOSURE; FOOD CONTAMINATION; HUMANS; INSECTICIDES; ISOMERISM; MALE; MICROSOMES, LIVER; MODELS, BIOLOGICAL; PERMETHRIN; RATS; RATS, LONG-EVANS; REGIONAL BLOOD FLOW; RISK ASSESSMENT; TISSUE DISTRIBUTION;

EID: 84867838198     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs236     Document Type: Article

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