Developmental neurotoxicity of pyrethroid insecticides: Critical review and future research needs

Environmental Health Perspectives

Volumn 113, Issue 2, 2005, Pages 123-136

  Shafer, Timothy J ^a   Meyer, Douglas A ^b   Crofton, Kevin M ^a,b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Age dependent toxicity; Biologically based dose response model; Developmental neurotoxicity; Mode of action; Physiologically based pharmacokinetic model; Pyrethroid; Risk assessment; Voltage sensitive sodium channel

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; ALLETHRIN; CIPERMETHRIN; CYFLUTHRIN; CYHALOTHRIN; DELTAMETHRIN; FENVALERATE; INSECTICIDE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR; MUSCARINIC RECEPTOR; PERMETHRIN; PYRETHROID; SODIUM ION; VOLTAGE GATED SODIUM CHANNEL;

ACUTE TOXICITY; AGE DISTRIBUTION; CHOREOATHETOSIS; CLONIC SEIZURE; GENETIC HETEROGENEITY; MOTOR ACTIVITY; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DENSITY; REVIEW; STATISTICAL ANALYSIS; TREMOR;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; FEMALE; INSECTICIDES; MICE; MOTOR ACTIVITY; NEUROTOXICITY SYNDROMES; PREGNANCY; PYRETHRINS; RATS; RECEPTORS, MUSCARINIC; RESEARCH DESIGN; RISK ASSESSMENT; SODIUM CHANNELS;

EID: 14744273163     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.7254     Document Type: Review

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